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IMGT/PROTEIN-DB and IMGT/3Dstructure-DB: Label definitions for IG, TR and MHC

Click here for IMGT/PROTEIN-DB and IMGT/3Dstructure-DB: Standardized keywords and labels for IG, TR and MHC.

Label name	Definition
I-ALPHA	MHC-I-Alpha chain comprising a G-ALPHA1, a G-ALPHA2 and a C-LIKE-DOMAIN
II-ALPHA	MHC-II-Alpha chain comprising a G-ALPHA and a C-LIKE-DOMAIN
II-BETA	MHC-II-Beta chain comprising a G-BETA and a C-LIKE-DOMAIN
B2M	Beta-2-Microglobulin chain comprising a C-LIKE-DOMAIN
CH	C-DOMAINs of an IG-Heavy chain
CH1	C-DOMAIN corresponding to the CH1 exon coding region from an IG-Heavy chain
CH2	C-DOMAIN corresponding to the CH2 exon coding region from an IG-Heavy chain or to a part of the CH2 exon coding region from an IG-Heavy-Alpha chain
CH2-CH3	CH2 and CH3 C-DOMAINs from an IG-Heavy chain
CH2-CH3-CH4	CH2, CH3 and CH4 C-DOMAINs from an IG-Heavy chain
CH3	C-DOMAIN corresponding to the CH3 exon coding region, but without CH-S (if there is one), from an IG-Heavy chain
CH4	C-DOMAIN corresponding to the CH4 exon coding region, but without CH-S (if there is one), from an IG-Heavy chain
CH5	C-DOMAIN corresponding to the CH5 exon coding region from an IG-Heavy chain
CH6	C-DOMAIN corresponding to the CH6 exon coding region from an IG-Heavy chain
CH7	C-DOMAIN corresponding to the CH7 exon coding region from an IG-Heavy chain
CL	C-DOMAIN of an IG-Light chain
CODING-REGION	amino acid coding region sequence from INIT-DOCON to STOP-CODON (not included), and corresponding nucleotide sequence extracted from cDNA sequences and/or built by artificial exon joining from genomic DNA sequences
C-ALPHA	C-DOMAIN of a TR-Alpha chain
C-BETA	C-DOMAIN of a TR-Beta chain
C-BETA-1	C-DOMAIN of a TR-Beta-1 chain
C-BETA-2	C-DOMAIN of a TR-Beta-2 chain
C-DELTA	C-DOMAIN of a TR-Delta chain
C-DOMAIN	IG or TR characteristic domain corresponding to a complete C-REGION or to a part of a C-REGION, depending on the IG or TR chain
C-GAMMA	C-DOMAIN of a TR-Gamma chain
C-GAMMA-1	C-DOMAIN of a TR-Gamma-1 chain
C-GAMMA-2	C-DOMAIN of a TR-Gamma-2 chain
C-IOTA	C-DOMAIN of a C-IOTA chain
C-IOTA-1	C-DOMAIN of a C-IOTA-1 chain
C-IOTA-2	C-DOMAIN of a C-IOTA-2 chain
C-IOTA-3	C-DOMAIN of a C-IOTA-3 chain
C-IOTA-4	C-DOMAIN of a C-IOTA-4 chain
C-KAPPA	C-DOMAIN of an IG-Light-Kappa chain
C-LAMBDA	C-DOMAIN of an IG-Light-Lambda chain
C-LIKE-DOMAIN	domain similar to an IG or TR C-DOMAIN, found in proteins other than IG or TR
FAB-ALPHA_KAPPA	Fab comprising the VH-CH1 domains from a H-ALPHA chain and a L-KAPPA chain
FAB-ALPHA-1_KAPPA	Fab comprising the VH-CH1 domains from a H-ALPHA-1 chain and a L-KAPPA chain
FAB-ALPHA-2_KAPPA	Fab comprising the VH-CH1 domains from a H-ALPHA-2 chain and a L-KAPPA chain
FAB-DELTA_KAPPA	Fab comprising the VH-CH1 domains from a H-DELTA chain and a L-KAPPA chain
FAB-EPSILON_KAPPA	Fab comprising the VH-CH1 domains from a H-EPSILON chain and a L-KAPPA chain
FAB-GAMMA-1_KAPPA	Fab comprising the VH-CH1 domains from a H-GAMMA-1 chain and a L-KAPPA chain
FAB-GAMMA-2_KAPPA	Fab comprising the VH-CH1 domains from a H-GAMMA-2 chain and a L-KAPPA chain
FAB-GAMMA-2-A_KAPPA	Fab comprising the VH-CH1 domains from a H-GAMMA-2-A chain and a L-KAPPA chain
FAB-GAMMA-2-B_KAPPA	Fab comprising the VH-CH1 domains from a H-GAMMA-2-B chain and a L-KAPPA chain
FAB-GAMMA-2-C_KAPPA	Fab comprising the VH-CH1 domains from a H-GAMMA-2-C chain and a L-KAPPA chain
FAB-GAMMA-3_KAPPA	Fab comprising the VH-CH1 domains from a H-GAMMA-3 chain and a L-KAPPA chain
FAB-GAMMA-4_KAPPA	Fab comprising the VH-CH1 domains from a H-GAMMA-4 chain and a L-KAPPA chain
FAB-MU_KAPPA	Fab comprising the VH-CH1 domains from a H-MU chain and a L-KAPPA chain
FAB-ALPHA_LAMBDA	Fab comprising the VH-CH1 domains from a H-ALPHA chain and a L-LAMBDA chain
FAB-ALPHA-1_LAMBDA	Fab comprising the VH-CH1 domains from a H-ALPHA-1 chain and a L-LAMBDA chain
FAB-ALPHA-2_LAMBDA	Fab comprising the VH-CH1 domains from a H-ALPHA-2 chain and a L-LAMBDA chain
FAB-DELTA_LAMBDA	Fab comprising the VH-CH1 domains from a H-DELTA chain and a L-LAMBDA chain
FAB-EPSILON_LAMBDA	Fab comprising the VH-CH1 domains from a H-EPSILON chain and a L-LAMBDA chain
FAB-GAMMA-1_LAMBDA	Fab comprising the VH-CH1 domains from a H-GAMMA-1 chain and a L-LAMBDA chain
FAB-GAMMA-2_LAMBDA	Fab comprising the VH-CH1 domains from a H-GAMMA-2 chain and a L-LAMBDA chain
FAB-GAMMA-2-A_LAMBDA	Fab comprising the VH-CH1 domains from a H-GAMMA-2-A chain and a L-LAMBDA chain
FAB-GAMMA-2-B_LAMBDA	Fab comprising the VH-CH1 domains from a H-GAMMA-2-B chain and a L-LAMBDA chain
FAB-GAMMA-2-C_LAMBDA	Fab comprising the VH-CH1 domains from a H-GAMMA-2-C chain and a L-LAMBDA chain
FAB-GAMMA-3_LAMBDA	Fab comprising the VH-CH1 domains from a H-GAMMA-3 chain and a L-LAMBDA chain
FAB-GAMMA-4_LAMBDA	Fab comprising the VH-CH1 domains from a H-GAMMA-4 chain and a L-LAMBDA chain
FAB-MU_LAMBDA	Fab comprising the VH-CH1 domains from a H-MU chain and a L-LAMBDA chain
F(AB')2-ALPHA_KAPPA	F(ab')2 comprising the VH-CH1 domains from two H-ALPHA chains and two L-KAPPA chains
F(AB')2-ALPHA-1_KAPPA	F(ab')2 comprising the VH-CH1 domains from two H-ALPHA-1 chains and two L-KAPPA chains
F(AB')2-ALPHA-2_KAPPA	F(ab')2 comprising the VH-CH1 domains from two H-ALPHA-2 chains and two L-KAPPA chains
F(AB')2-DELTA_KAPPA	F(ab')2 comprising the VH-CH1 domains from two H-DELTA chains and two L-KAPPA chains
F(AB')2-EPSILON_KAPPA	F(ab')2 comprising the VH-CH1 domains from two H-EPSILON chains and two L-KAPPA chains
F(AB')2-GAMMA-1_KAPPA	F(ab')2 comprising the VH-CH1 domains from two H-GAMMA-1 chains and two L-KAPPA chains
F(AB')2-GAMMA-2_KAPPA	F(ab')2 comprising the VH-CH1 domains from two H-GAMMA-2 chains and two L-KAPPA chains
F(AB')2-GAMMA-2-A_KAPPA	F(ab')2 comprising the VH-CH1 domains from two H-GAMMA-2-A chains and two L-KAPPA chains
F(AB')2-GAMMA-2-B_KAPPA	F(ab')2 comprising the VH-CH1 domains from two H-GAMMA-2-B chains and two L-KAPPA chains
F(AB')2-GAMMA-2-C_KAPPA	F(ab')2 comprising the VH-CH1 domains from two H-GAMMA-2-C chains and two L-KAPPA chains
F(AB')2-GAMMA-3_KAPPA	F(ab')2 comprising the VH-CH1 domains from two H-GAMMA-3 chains and two L-KAPPA chains
F(AB')2-GAMMA-4_KAPPA	F(ab')2 comprising the VH-CH1 domains from two H-GAMMA-4 chains and two L-KAPPA chains
F(AB')2-MU_KAPPA	F(ab')2 comprising the VH-CH1 domains from two H-MU chains and two L-KAPPA chains
F(AB')2-ALPHA_LAMBDA	F(ab')2 comprising the VH-CH1 domains from two H-ALPHA chains and two L-LAMBDA chains
F(AB')2-ALPHA-1_LAMBDA	F(ab')2 comprising the VH-CH1 domains from two H-ALPHA-1 chains and two L-LAMBDA chains
F(AB')2-ALPHA-2_LAMBDA	F(ab')2 comprising the VH-CH1 domains from two H-ALPHA-2 chains and two L-LAMBDA chains
F(AB')2-DELTA_LAMBDA	F(ab')2 comprising the VH-CH1 domains from two H-DELTA chains and two L-LAMBDA chains
F(AB')2-EPSILON_LAMBDA	F(ab')2 comprising the VH-CH1 domains from two H-EPSILON chains and two L-LAMBDA chains
F(AB')2-GAMMA-1_LAMBDA	F(ab')2 comprising the VH-CH1 domains from two H-GAMMA-1 chains and two L-LAMBDA chains
F(AB')2-GAMMA-2_LAMBDA	F(ab')2 comprising the VH-CH1 domains from two H-GAMMA-2 chains and two L-LAMBDA chains
F(AB')2-GAMMA-2-A_LAMBDA	F(ab')2 comprising the VH-CH1 domains from two H-GAMMA-2-A chains and two L-LAMBDA chains
F(AB')2-GAMMA-2-B_LAMBDA	F(ab')2 comprising the VH-CH1 domains from two H-GAMMA-2-B chains and two L-LAMBDA chains
F(AB')2-GAMMA-2-C_LAMBDA	F(ab')2 comprising the VH-CH1 domains from two H-GAMMA-2-C chains and two L-LAMBDA chains
F(AB')2-GAMMA-3_LAMBDA	F(ab')2 comprising the VH-CH1 domains from two H-GAMMA-3 chains and two L-LAMBDA chains
F(AB')2-GAMMA-4_LAMBDA	F(ab')2 comprising the VH-CH1 domains from two H-GAMMA-4 chains and two L-LAMBDA chains
F(AB')2-MU_LAMBDA	F(ab')2 comprising the VH-CH1 domains from two H-MU chains and two L-LAMBDA chains
FC-ALPHA	Fc comprising the CH2-CH3 domains from two H-ALPHA chains
FC-ALPHA-1	Fc comprising the CH2-CH3 domains from two H-ALPHA-1 chains
FC-ALPHA-2	Fc comprising the CH2-CH3 domains from two H-ALPHA-2 chains
FC-DELTA	Fc comprising the CH2-CH3 domains from two H-DELTA chains
FC-EPSILON	Fc comprising the CH2-CH3-CH4 domains from two H-EPSILON chains
FC-GAMMA-1	Fc comprising the CH2-CH3 domains from two H-GAMMA-1 chains
FC-GAMMA-2	Fc comprising the CH2-CH3 domains from two H-GAMMA-2 chains
FC-GAMMA-2-A	Fc comprising the CH2-CH3 domains from two H-GAMMA-2-A chains
FC-GAMMA-2-B	Fc comprising the CH2-CH3 domains from two H-GAMMA-2-B chains
FC-GAMMA-2-C	Fc comprising the CH2-CH3 domains from two H-GAMMA-2-C chains
FC-GAMMA-3	Fc comprising the CH2-CH3 domains from two H-GAMMA-3 chains
FC-GAMMA-4	Fc comprising the CH2-CH3 domains from two H-GAMMA-4 chains
FC-MU	Fc comprising the CH2-CH3-CH4 domains from two H-MU chains
FV-ALPHA_BETA	Fv comprising a V-ALPHA and a V-BETA domains
FV-GAMMA_DELTA	Fv comprising a V-GAMMA and a V-DELTA domains
FV-HEAVY_KAPPA	Fv comprising a VH and a V-KAPPA domains
FV-HEAVY_LAMBDA	Fv comprising a VH and a V-LAMBDA domains
G-ALPHA	G-DOMAIN corresponding to domain 1 of a MHC-II-Alpha chain
G-ALPHA1	G-DOMAIN corresponding to domain 1 of a MHC-I-Alpha chain
G-ALPHA2	G-DOMAIN corresponding to domain 2 of a MHC-I-Alpha chain
G-ALPHA1-LIKE	domain of non-MHC similar to G-ALPHA1
G-ALPHA2-LIKE	domain of non-MHC similar to G-ALPHA2
G-BETA	G-DOMAIN corresponding to domain 1 of a MHC-II-Beta chain
G-DOMAIN	MHC characteristic groove domain corresponding to domain 1 or domain 2 of a MHC-I Alpha chain, to the domain 1 of a MHC-II-Alpha or to the domain 2 of a MHC-II-Beta chain
G-LIKE-DOMAIN	domain of non-MHC similar to a MHC G-DOMAIN
H-ALPHA	IG-Heavy-Alpha chain comprising VH, CH1,CH2 and CH3 domains
H-ALPHA-1	IG-Heavy-Alpha-1 chain comprising VH, CH1,CH2 and CH3 domains
H-ALPHA-2	IG-Heavy-Alpha-2 chain comprising VH, CH1,CH2 and CH3 domains
H-DELTA	IG-Heavy-Delta chain comprising VH, CH1,CH2 and CH3 domains
H-EPSILON	IG-Heavy-Epsilon chain comprising VH, CH1,CH2, CH3 and CH4 domains
H-GAMMA-1	IG-Heavy-Gamma-1 chain comprising VH, CH1,CH2 and CH3 domains
H-GAMMA-2	IG-Heavy-Gamma-2 chain comprising VH, CH1,CH2 and CH3 domains
H-GAMMA-2-A	IG-Heavy-Gamma-2-a chain comprising VH, CH1,CH2 and CH3 domains
H-GAMMA-2-B	IG-Heavy-Gamma-2-b chain comprising VH, CH1,CH2 and CH3 domains
H-GAMMA-2-C	IG-Heavy-Gamma-2-c chain comprising VH, CH1,CH2 and CH3 domains
H-GAMMA-3	IG-Heavy-Gamma-3 chain comprising VH, CH1,CH2 and CH3 domains
H-GAMMA-4	IG-Heavy-Gamma-4 chain comprising VH, CH1,CH2 and CH3 domains
H-MU	IG-Heavy-Mu chain comprising VH, CH1,CH2, CH3 and CH4 domains
IG-ALPHA_KAPPA	IG receptor comprising two H-ALPHA and two L-KAPPA chains
IG-ALPHA-1_KAPPA	IG receptor comprising two H-ALPHA-1 and two L-KAPPA chains
IG-ALPHA-2_KAPPA	IG receptor comprising two H-ALPHA-2 and two L-KAPPA chains
IG-DELTA_KAPPA	IG receptor comprising two H-DELTA and two L-KAPPA chains
IG-EPSILON_KAPPA	IG receptor comprising two H-EPSILON and two L-KAPPA chains
IG-GAMMA-1_KAPPA	IG receptor comprising two H-GAMMA-1 and two L-KAPPA chains
IG-GAMMA-2_KAPPA	IG receptor comprising two H-GAMMA-2 and two L-KAPPA chains
IG-GAMMA-2-A_KAPPA	IG receptor comprising two H-GAMMA-2-A and two L-KAPPA chains
IG-GAMMA-2-B_KAPPA	IG receptor comprising two H-GAMMA-2-B and two L-KAPPA chains
IG-GAMMA-2-C_KAPPA	IG receptor comprising two H-GAMMA-2-C and two L-KAPPA chains
IG-GAMMA-3_KAPPA	IG receptor comprising two H-GAMMA-3 and two L-KAPPA chains
IG-GAMMA-4_KAPPA	IG receptor comprising two H-GAMMA-4 and two L-KAPPA chains
IG-MU_KAPPA	IG receptor comprising two H-MU and two L-KAPPA chains
IG-ALPHA_LAMBDA	IG receptor comprising two H-ALPHA and two L-LAMBDA chains
IG-ALPHA-1_LAMBDA	IG receptor comprising two H-ALPHA-1 and two L-LAMBDA chains
IG-ALPHA-2_LAMBDA	IG receptor comprising two H-ALPHA-2 and two L-LAMBDA chains
IG-DELTA_LAMBDA	IG receptor comprising two H-DELTA and two L-LAMBDA chains
IG-EPSILON_LAMBDA	IG receptor comprising two H-EPSILON and two L-LAMBDA chains
IG-GAMMA-1_LAMBDA	IG receptor comprising two H-GAMMA-1 and two L-LAMBDA chains
IG-GAMMA-2_LAMBDA	IG receptor comprising two H-GAMMA-2 and two L-LAMBDA chains
IG-GAMMA-2-A_LAMBDA	IG receptor comprising two H-GAMMA-2-A and two L-LAMBDA chains
IG-GAMMA-2-B_LAMBDA	IG receptor comprising two H-GAMMA-2-B and two L-LAMBDA chains
IG-GAMMA-2-C_LAMBDA	IG receptor comprising two H-GAMMA-2-C and two L-LAMBDA chains
IG-GAMMA-3_LAMBDA	IG receptor comprising two H-GAMMA-3 and two L-LAMBDA chains
IG-GAMMA-4_LAMBDA	IG receptor comprising two H-GAMMA-4 and two L-LAMBDA chains
IG-MU_LAMBDA	IG receptor comprising two H-MU and two L-LAMBDA chains
IG-MU_IOTA	IG receptor comprising two H-MU and two L-IOTA chains
IG-MU_IOTA-1	IG receptor comprising two H-MU and two L-IOTA-1 chains
IG-MU_IOTA-2	IG receptor comprising two H-MU and two L-IOTA-2 chains
IG-MU_IOTA-3	IG receptor comprising two H-MU and two L-IOTA-3 chains
IG-MU_IOTA-4	IG receptor comprising two H-MU and two L-IOTA-4 chains
L-IOTA	IG-Light-Iota chain comprising a V-IOTA and a C-IOTA domains
L-IOTA-1	IG-Light-Iota chain comprising a V-IOTA and a C-IOTA-1 domains
L-IOTA-2	IG-Light-Iota chain comprising a V-IOTA and a C-IOTA-2 domains
L-IOTA-3	IG-Light-Iota chain comprising a V-IOTA and a C-IOTA-3 domains
L-IOTA-4	IG-Light-Iota chain comprising a V-IOTA and a C-IOTA-4 domains
L-KAPPA	IG-Light-Kappa chain comprising a V-KAPPA and a C-KAPPA domains
L-LAMBDA	IG-Light-Lambda chain comprising a V-LAMBDA and a C-LAMBDA domains
MHC-I-ALPHA_B2M	MHC receptor comprising one I-ALPHA and one B2M chains
MHC-II-ALPHA_BETA	MHC receptor comprising one II-ALPHA and one II-BETA chains
SCFV-ALPHA-BETA	scFv comprising a V-ALPHA and a V-BETA domains
SCFV-GAMMA-DELTA	scFv comprising a V-GAMMA and a V-DELTA domains
SCFV-HEAVY-KAPPA	scFv comprising a VH and a V-KAPPA domains
SCFV-HEAVY-LAMBDA	scFv comprising a VH and a V-LAMBDA domains
TR-ALPHA	TR-Alpha chain comprising a V-ALPHA and a C-ALPHA domains
TR-BETA-1	TR-Beta-1 chain comprising a V-BETA and a C-BETA-1 domains
TR-BETA-2	TR-Beta-2 chain comprising a V-BETA and a C-BETA-2 domains
TR-DELTA	TR-DELTA chain comprising a V-DELTA and a C-DELTA domains
TR-GAMMA-1	TR-GAMMA-1 chain comprising a V-GAMMA and a C-GAMMA-1 domains
TR-GAMMA-2	TR-GAMMA-2 chain comprising a V-GAMMA and a C-GAMMA-2 domains
TR-ALPHA_BETA-1	TR receptor comprising one TR-ALPHA and one TR-BETA-1 chains
TR-ALPHA_BETA-2	TR receptor comprising one TR-ALPHA and one TR-BETA-2 chains
TR-GAMMA-1_DELTA	TR receptor comprising one TR-GAMMA-1 and one TR-DELTA chains
TR-GAMMA-2_DELTA	TR receptor comprising one TR-GAMMA-2 and one TR-DELTA chains
V-ALPHA	V-DOMAIN of a TR-Alpha chain
V-BETA	V-DOMAIN of a TR-Beta chain
V-DELTA	V-DOMAIN of a TR-Delta chain
V-DOMAIN	IG or TR characteristic domain corresponding to the V-J-REGION or the V-D-J-REGION of an IG or TR chain
V-GAMMA	V-DOMAIN of a TR-Gamma chain
VH	V-DOMAIN of an IG-Heavy chain
VH-CH1	VH and CH1 domains from an IG-Heavy chain
V-KAPPA	V-DOMAIN of an IG-Light-Kappa chain
VL	V-DOMAIN of an IG-Light chain
V-IOTA	V-DOMAIN of an IG-Light-Iota chain
V-LAMBDA	V-DOMAIN of an IG-Light-Lambda chain
V-LIKE-DOMAIN	domain similar to an IG or TR V-DOMAIN, found in proteins other than IG or TR

Created: 13/09/2002
Last updated: Wednesday, 29-Jun-2011 17:04:15 CEST
Authors: Aude Thiriot and Marie-Paule Lefranc
Editor: Chantal Ginestoux
Contact: Marie-Paule Lefranc

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