IMGT/V-QUEST reference directory releases

Citing IMGT/V-QUEST: Brochet, X. et al., Nucl. Acids Res. 36, W503-508 (2008). PMID: 18503082 Giudicelli, V., Brochet, X., Lefranc, M.-P., Cold Spring Harb Protoc. 2011 Jun 1;2011(6). pii: pdb.prot5633. doi: 10.1101/pdb.prot5633. PMID: 21632778 Abstract also in IMGT booklet with generous provision from Cold Spring Harbor (CSH) Protocols (high res) (lower res)

IMGT/V-QUEST programme version: 3.2.23 (6 January 2012) - IMGT/V-QUEST reference directory release: 201201-5 (6 January 2012)

• Release 201201-5 (6 January 2012)
  • Addition of the Homo sapiens IGHV3-11*05 gene and allele.

• Release 201148-5 (2 December 2011)
  • Addition of the Mus musculus IGKV14-126*01 gene and allele.

• Release 201145-2 (8 November 2011)
  • Addition of the Mus musculus IGHV11-1*02 gene and allele.

  • Addition of the Oryctolagus cuniculus IGHV1S69*01 gene and allele.

  • Update of the Mus musculus TRDV numbering: positions 8A and 84A have been included in order to facilitate alignements of Mus musculus TRAV and TRDV genes and alleles.

• Release 201139-5 (30 September 2011)
  • Update of the Bos taurus TRG reference directory. It includes 38 TRGV genes and alleles: TRGV1-1*01, TRGV1-1*02, TRGV1-1*03, TRGV2-1*01, TRGV3-1*01, TRGV3-1*02, TRGV3-2*01, TRGV3-2*02, TRGV4-1*01, TRGV5-1*01, TRGV5-1*02, TRGV5-1*03, TRGV5-1*04, TRGV5-1*05, TRGV5-2*01, TRGV5-2*02, TRGV5-2*03, TRGV5-2*04, TRGV5-2*05, TRGV5-2*06, TRGV5-2*07, TRGV5-2*08, TRGV5-2*09, TRGV5-2*10, TRGV6-1*01, TRGV6-1*02, TRGV6-2*01, TRGV7-1*01, TRGV7-1*02, TRGV8-1*01, TRGV8-2*01, TRGV8-2*02, TRGV8-3*01, TRGV8-3*02, TRGV8-4*01, TRGV9-1*01, TRGV9-2*01, TRGV10-1*01
    and 16 TRGJ 16 genes and alleles: TRGJ1-1*01, TRGJ1-2*01, TRGJ1-2*02, TRGJ1-2*03, TRGJ2-1*01, TRGJ2-1*02, TRGJ2-1*03, TRGJ2-2*01, TRGJ2-2*02, TRGJ2-2*03, TRGJ3-1*01, TRGJ3-1*02, TRGJ4-1*01, TRGJ4-2*01, TRGJ5-1*01, TRGJ6-1*01.

• Release 201138-4 (22 September 2011)
  • The Mus musculus IGKV10-96*06 gene and allele has been added.

• Release 201135-3 (31 August 2011)
  • The sequence of Mus musculus TRAV12D-3*01 gene and allele has been updated.
    The Mus musculus TRAV12D-3*04 gene and allele has been removed.

• Release 201130-5 (29 July 2011)
  • The Mus musculus IGKV20-101-2*01 gene and allele has been restored.

• Release 201130-2 (26 July 2011)
  • Addition of the Mus musculus TRBJ2-6*01 gene and allele.

• Release 201126-1 (27 June 2011)
  • Addition of 3 Mus musculus IGHD alleles: IGHD2-9*02, IGHD2-10*02 and IGHD2-11*02.
    Addition of 1 Mus musculus IGHJ alleles: IGHJ2*02 (the reference sequence is S73821, note that S77041 became the reference sequence of IGHJ2*03).

  • Addition of a new species: Zebrafish (Danio rerio):
    • Addition of 41 IGHV genes and alleles (35 F, 5 ORF and 1 P), 7 IGHD (7 F) and 7 IGHJ (7 F).
    • Addition of 11 IGIV genes and alleles (8 F, 2 ORF and 1 P) and 8 IGHJ (6 F, 1 ORF and 1 P).

• Release 201117-5 (29 April 2011)
  • Addition of the Mus musculus IGKV20-101-2*01 gene and allele.

• Release 201110-1 (7 March 2011)
  Addition of the Homo sapiens IGHV3-NL1 gene and 31 Homo sapiens IGHV alleles sequenced from Papua (New Guinea): IGHV1-2*05, IGHV3-21*03, IGHV3/OR16-10*03, IGHV1-8*02, IGHV1-18*03, IGHV3-7*03, IGHV3-9*02, IGHV3-11*04, IGHV3-13*04, IGHV3-21*04, IGHV3-25*04, IGHV3-33*06, IGHV3-48*04, IGHV3-53*04, IGHV3-NL1*01, IGHV4-28*06, IGHV4-30-2*05, IGHV7-4-1*04, IGHV7-4-1*05, IGHV1/OR15-1*03, IGHV1/OR15-1*04, IGHV1/OR15-2*02, IGHV1/OR15-2*03, IGHV3/OR15-7*05, IGHV3/OR16-6*02, IGHV3/OR16-8*02, IGHV3-25*05, IGHV3-71*02, IGHV3-71*03, IGHV4/OR15-8*03, IGHV7-34-1*02.

• Release 201104-4 (27 January 2011)
  Addition of a new species: Camel (Camelus dromedarius):
  • Addition of 13 Camelus dromedarius TRDV genes and alleles (13 F): TRDV1S1*01, TRDV1S1*02, TRDV1S2*01, TRDV1S2*02, TRDV1S3*01, TRDV1S4*01, TRDV1S4*02, TRDV1S5*01, TRDV1S6*01, TRDV2S1*01, TRDV2S2*01, TRDV2S3*01, TRDV4S1*01

• Release 201051-1 (20 December 2010)
  • Addition of 2 Homo sapiens IGKV orphon genes: IGKV1/OR2-118 and IGKV2/OR2-7D.

• Release 201048-1 (29 November 2010)
  • Addition of 51 new Mus musculus TRAV genes and alleles resulting from the expertise of the triplicated zone of the TRAV locus in the Mus musculus C57BL/6J strain:
    TRAV3D-3*02 , TRAV3N-2*01 , TRAV3N-3*01 , TRAV4N-4*01 , TRAV5D-4*05 , TRAV5N-2*01 , TRAV5N-3*01 , TRAV5N-4*01 , TRAV6-3*02 , TRAV6-4*03 , TRAV6-5*04 , TRAV6D-7*04 , TRAV6N-5*01 , TRAV6N-6*01 , TRAV6N-7*01 , TRAV7-2*02 , TRAV7-3*04 , TRAV7-4*02 , TRAV7D-6*02 , TRAV7N-4*01 , TRAV7N-5*01 , TRAV7N-6*01 , TRAV8-1*03 , TRAV8D-2*03 , TRAV8N-2*01 , TRAV9-1*02 , TRAV9N-1*01 , TRAV9N-2*01 , TRAV9N-2*01 , TRAV9N-3*01 , TRAV9N-4*01 , TRAV10N*01 , TRAV11N*01 , TRAV12N-1*01 , TRAV12N-2*01 , TRAV12N-3*01 , TRAV13D-3*02 , TRAV13D-4*03 , TRAV13N-1*01 , TRAV13N-2*01 , TRAV13N-3*01 , TRAV13N-4*01 , TRAV14D-2*03 , TRAV14D-3/DV8*08 , TRAV14N-1*01 , TRAV14N-3*01 , TRAV15D-3*02 , TRAV15N-1*01 , TRAV15N-2*01 , TRAV15N-3*01 , TRAV16N*01

  • Update of the sequence of Bos taurus TRGV7-1*01 allele.

• Release 201030-3 (28th of July 2010)
  Addition of a new species: dog (Canis lupus familiaris):
  • 35 TRBV genes and alleles (19 F, 1 ORF and 15 in-frame P)
  • 1 TRBD gene and allele (1 F)
  • 6 TRBJ gene and allele (5F and 1 in-frame P)
  • 9 TRGV genes and alleles (9 F)
  • 15 TRBJ gene and allele (7F and 2 ORF and 6 in-frame P)

  Addition of the bovine TRDV IMGT/V-QUEST reference sequences: 73 Bos taurus TRDV genes and alleles (65 F, 7 ORF and 1 in-frame P)

  Addition of the bovine TRDD IMGT/V-QUEST reference sequences: 5 Bos taurus TRDD genes and alleles (F)

  Addition of the bovine TRDJ IMGT/V-QUEST reference sequences: 3 Bos taurus TRDJ genes and alleles (F)

  Update of the human IGHV IMGT/V-QUEST reference sequences:
  - Addition of the orphon Homo sapiens IGHV1/OR21-1*01
  - The gene and allele Homo sapiens IGHJ2P*01 has been removed

  Update of the numbering of the human and mouse TRAV genes and alleles

  Short name of the species, encoded on 6 characters (for example Musmus for Mus musculus) are indicated with genes names for IMGT/V-QUEST reference directory sets that may include genes from several species: mouse, teleostei and chondrichthyes sets.

IMGT/V-QUEST Search page
IMGT/V-QUEST Documentation

Contact IMGT/V-QUEST, Montpellier, France : Véronique Giudicelli (Veronique.Giudicelli@igh.cnrs.fr) and Marie-Paule Lefranc (Marie-Paule.Lefranc@igh.cnrs.fr)

Created: 07/07/2010
Last updated: 28/07/2010
Authors: Véronique Giudicelli and Marie-Paule Lefranc.
Marie-Paule.Lefranc@igh.cnrs.fr

Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT, and cited as "IMGT, the international ImMunoGeneTics information system® http://www.imgt.org (Initiator and coordinator: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Research, 27, 209-212 (1999) Cover of NAR; Ruiz, M. et al., Nucleic Acids Research, 28, 219-221 (2000); Lefranc, M.-P., Nucleic Acids Research, 29, 207-209 (2001), Lefranc, M.-P., Nucleic Acids Res., 31, 307-310 (2003) Full text; Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004), Lefranc, M.-P. et al., Nucleic Acids Res., 33, D593-D597 (2005) Full text; Lefranc, M.-P. et al., Nucleic Acids Research 2009 37(Database issue): D1006-D1012; doi:10.1093/nar/gkn838 Full text.

For any other use please contact Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr.

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