IMGT Index

Domain type and domain set

The 'domain type' concept identifies the type of a domain. A domain is a subunit of a chain characterized by its three-dimensional (3D structure).

The 'domain type' concept is part of the 'IDENTIFICATION' concept of IMGT-ONTOLOGY [1]

In IMGT, the 'domain type' concept has three main concepts:

the V type (V for variable)
the C type (C for constant)
the G type (G for groove)
- 'V type' identifies the domain type of domains described as V-DOMAIN and V-LIKE-DOMAIN (Table) [2].
- 'C type' identifies the domain type of domains described as C-DOMAIN and C-LIKE-DOMAIN (Table) [3].
- 'G type' identifies the domain type of domains described as G-DOMAIN and G-LIKE-DOMAIN (Table) [4].

Domain sequences or domain structures (in reality) that are identified by a given 'domain type' concept make up a given domain set. Thus:

'V set' refers to a set of domain sequences or structures (in reality) that are identified by the 'V type' concept.
'C set' refers to a set of domain sequences or structures (in reality) that are identified by the 'C type' concept.
'G set' refers to a set of domain sequences or structures (in reality) that are identified by the 'G type' concept.

References:
[1]	Giudicelli, V. and Lefranc, M-P., Bioinformatics, 15, 1047-1054 (1999) PMID: 10745995, LIGM:221
[2]	Lefranc, M.-P. et al., Dev. Comp. Immunol., 27, 55-77 (2003) PMID: 12477501 LIGM:268
[3]	Lefranc, M.-P. et al., Dev. Comp. Immunol., 29, 185-203 (2005) PMID: 15572068 LIGM:293
[4]	Lefranc, M.-P. et al., Dev. Comp. Immunol., 2005, 29, 917-938 PMID: 15936075 LIGM: 296

See also:

Created: 10/04/2006
Author: Marie-Paule Lefranc
Editor: Chantal Ginestoux
Contact: Marie-Paule Lefranc

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For any other use please contact Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr.

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