Fusion proteins for immune applications (FPIA)
Fusion proteins for immune applications (FPIA) result generally from the fusion of one or several region and/or domain of protein(s) with the Fc of an IG in a '(protein)2:Fc' format. The Fc is used for its effector properties. They are currently designated with the suffix (stem) '-cept' in INN.
FPIA (Fusion proteins for immune applications) and CPCA (Composite proteins for clinical applications) correspond to in vitro engineered proteins of the WHO/INN programme. These categories FPIA and CPCA will be proposed for the INN definition in publication lists.