IMGT Index

IMGT Nomenclature Committee (IMGT-NC)

Chairperson

Marie-Paule Lefranc (Marie-Paule.Lefranc@igh.cnrs.fr)
Senior Member of the Institut Universitaire de France; Professor Université Montpellier II
IMGT, LIGM IGH, UPR CNRS 1142, Montpellier, France

Objectives

The IMGT Nomenclature Committee (IMGT-NC) is responsible for the standardized classification and nomenclature of the immunoglobulins (IG) and T cell receptors (TR) of human and other vertebrate species. IMGT-NC Subcommittee for immunoglobulins and T cell receptors, and of the immunoglobulin superfamily (IgSF) and the major histocompatibility complex superfamily (MhcSF) (IMGT-NC Subcommittee for IgSF and MhcSF). in IMGT, the international ImMunoGeneTics information system® http://www.imgt.org [1].

The IMGT-NC Subcommittee for immunoglobulins and T cell receptors is the 'WHO-IUIS Nomenclature Subcommittee for immunoglobulins and T cell receptors'.

Rules for the nomenclature are described in the IMGT Scientific chart and are based on the concept of CLASSIFICATION of IMGT-ONTOLOGY [2].
WHO-IUIS Nomenclature Subcommittee for immunoglobulins and T cell receptors report - Aug. 2007 [6,7]

The IMGT Nomenclature Committee (IMGT-NC) is responsible of the coherence of the IG, TR and MHC gene and allele nomenclature, as well as that of the related proteins, with the concepts of IDENTIFICATION, DESCRIPTION and NUMEROTATION of IMGT-ONTOLOGY in IMGT, the international ImMunoGeneTics information system® http://www.imgt.org [1].

IMGT-NC works in close collaboration with

• the IMGT Annotation Committee
• the Human Genome Organization (HUGO) Nomenclature Committe (HGNC) [3]. All the IMGT human IG and TR genes were approved by HGNC in 1999 [4,5] and can be queried in IMGT/GENE-DB. Links on individual entries between IMGT, NCBI genome, Entrez Gene and GeneCards have been established.
• The WHO Nomenclature Committee for Factors of the HLA System.
• the Mouse Genomic Nomenclature Committee (MGNC)

• Allele
• CLASSIFICATION
• DESCRIPTION
• Gene
• IDENTIFICATION
• IMGT Annotation Committee
• IMGT Experts
• IMGT/GENE-DB
• IMGT Informatics Committee
• IMGT Interface Committee
• IMGT-ONTOLOGY
• IMGT Scientific chart
• IMGT Scientific Committee
• Nomenclature
• NUMEROTATION

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Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Research, 27, 209-212 (1999) Cover of NAR; Ruiz, M. et al., Nucleic Acids Research, 28, 219-221 (2000); Lefranc, M.-P., Nucleic Acids Research, 29, 207-209 (2001); Lefranc, M.-P., Nucleic Acids Res., 31, 307-310 (2003); Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5, 45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33, D593-D597 (2005) Full text; Lefranc, M.-P. et al., Nucleic Acids Research 2009 37: D1006-D1012; doi:10.1093/nar/gkn838 Full text.
For any other use please contact Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr.

     

IMGT founder and director: Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr
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