IMGT/PROTEIN-DB (in development) will be a new database related to immunoglobulin and T cell receptor amino acid sequences in the IMGT, the international ImMunoGeneTics information system® http://www.imgt.org.
IMGT/PROTEIN-DB will allow a search per protein name and will be based on the CLASSIFICATION concept of IMGT-ONTOLOGY.
Although the implementation is still in progress, information on the translation of IG and TR genes and alleles is already available in IMGT Repertoire > Proteins and alleles [1-4].
Information on 3D structures is available in IMGT Repertoire > 2D and 3D structures and in IMGT/3Dstructure-DB.
The human IMGT IG and TR nomenclature [1-2] was approved by the HUman Genome Organization (HUGO) Gene Nomenclature Committee (HGNC) in 1999.
| [1] | Lefranc, M.-P. and Lefranc, G., The Immunoglobulin FactsBook, Academic Press, 458 pages (2001), ISBN: 012441351X. |
| [2] | Lefranc, M.-P. and Lefranc, G., The T cell receptor FactsBook, Academic Press, 398 pages (2001), ISBN: 0124413528. |
| [3] | Folch, G., Scaviner, D., Contet, V. and Lefranc, M.-P.,
Exp. Clin. Immunogenet., 17, 205-215 (2000),
PMID: 11096259,
LIGM:236
|
| [4] | Scaviner, D., Barbié, V., Ruiz, M. and Lefranc, M.-P.,
Exp. Clin. Immunogenet., 16, 234-240 (1999),
PMID: 10575277,
LIGM:218
|