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LOCALIZATION

The 'LOCALIZATION' axiom is one of the seven axioms of the Formal IMGT-ONTOLOGY or IMGT-Kaleidoscope [1-3].

The 'LOCALIZATION' axiom postulates that molecules, cells, organs, organisms or populations and their processes and relations have to be localized in time or space. At the molecular level in the field of immunogenetics, the concepts of localization allow to characterize the localization of IG and TR genes. The 'LOCALIZATION' axiom has generated concepts of localization, for example:

• the 'Locus' concept
• the 'Chromosomal orphon set' concept
• the 'Cassette' concept

References:

[1]	Giudicelli, V. and Lefranc, M.-P., Bioinformatics, 15, 1047-1054 (1999). PMID: 10745995, LIGM:221
[2]	Giudicelli, V. and Lefranc, M.-P. "Le paradigme IMGT-ONTOLOGY" In: Biologie Systémique Standards et modèles (Roux M. Ed.), Collection Ecrin, Omniscience, Presses Universitaires de France, Paris, 2007, Chapitre 6, pp143-164. ISBN: 978-2-916097-12-1
[3]	Duroux, P. et al., "IMGT-Kaleidoscope, the Formal IMGT-ONTOLOGY paradigm", Biochimie, 90, 570-583 (2008). Epub 2007 Sep11. PMID: 17949886

See also:

• CLASSIFICATION
• DESCRIPTION
• IDENTIFICATION
• IMGT-ONTOLOGY
• NUMEROTATION
• OBTENTION
• ORIENTATION

Created: 14/06/2007
Authors: Véronique Giudicelli and Marie-Paule Lefranc
Editor: Chantal Ginestoux
Contact: Marie-Paule Lefranc

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For any other use please contact Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr.

     

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