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Specificity

The specificity is the selective reactivity of an antibody for a native antigen or that of a T cell receptor for a peptide-MHC complex.

The 'specificity' concept identifies the nature of these antigens recognized by the immunoglobulins or T cell receptors. The specificity is defined for rearranged IG and TR sequences.

The definition of the specificities has been standardized to facilitate queries.

Click here for a List of the specificities available in IMGT/LIGM-DB.

Specificity can be queried from the "Taxonomy,..." module in IMGT/LIGM-DB.

The 'specificity' concept is part of the 'IDENTIFICATION' concept of IMGT-ONTOLOGY [1].

Specificity description

The specificity is described by the prefix "anti-" followed by the antigen name, or by the peptide-MHC complex designation.

For anti-idiotype, the antigen recognized by the isotype is shown separated by the sign ">".

Allelic forms of a ligand are shown by an asterisk followed by the polymorphic amino acid (single letter abbreviation) and its position.

Reference:
[1] Giudicelli, V. and Lefranc, M.-P., Bioinformatics, 15, 1047-1054 (1999) PMID:10745995, LIGM:221 pdf
See also:

© The list of the specificities available in IMGT/LIGM-DB and IMGT Repertoire and the description of the specificities are IMGT Copyright 2000-2001.