IMGT/3Dstructure-DB card: 1dvf

Colliers de Perles: IGH V-D-J-REGION
Colliers de Perles: IGK V-J-REGION

V-DOMAIN VH IGH V-D-J-REGION (PDB: 1dvf_B)

V-DOMAIN V-KAPPA IGK V-J-REGION (PDB: 1dvf_A)

A V-DOMAIN corresponds to the V-J-REGION or V-D-J-REGION of the immunoglobulin and T cell receptor chains.
This figure shows the two associated V-DOMAINs isolated from an antibody and constituting what is called a "Fv" (for "fragment variable")

Legend:

• CDR-IMGT regions are colored according to the IMGT color menu:
  IGK V-J-REGION: CDR1-IMGT (blue), CDR2-IMGT (green), CDR3-IMGT (dark green)
  IGH V-D-J-REGION: CDR1-IMGT (red), CDR2-IMGT (orange), CDR3-IMGT (purple).

• V-DOMAIN strands are colored according to the IMGT color menu for strand representation: A, B and C strands (orange), C' and C'' strands (green), D strand (yellow), E, F and G strands (blue).

• This image has been generated with the program RASMOL version 2.6 from the PDB file 1dvf, containing the atomic coordinates of the complex between Idiotope D1.3 -Antiidiotope E5.2. Both D1.3 (1dvf_A, 1dvf_B)and E5.2 (1dvf_C, 1dvf_D) are mouse antibodies (Mus musculus) IgG1, kappa. Only the D1.3 Fv is displayed here.

IMGT 2D and 3D representations (examples) in IMGT Repertoire.

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Created: 11/06/2001
Last updated: Tuesday, 15-Nov-2011 12:03:14 CET
Author: Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr
Editor: Elodie Foulquier
Contact: Marie-Paule Lefranc

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