IMGT Repertoire (IG and TR)

Lists of human Homo sapiens IG and TR genes, groups, loci and orphons and links between IMGT/GENE-DB, HGNC, Entrez Gene, GenAtlas and GeneCards

IG loci: Human

There are 3 major loci for the immunoglobulin (IG) genes and 12 chromosomal orphon sets [1].

• IG chromosomal orphon set
• List of the IG orphons per chromosome localization

IMGT loci and links with HGNC, Entrez Gene and OMIM

IMGT locus name	IMGT locus definition	Chromosomal localization	HGNC	Entrez Gene	OMIM
IGH locus	Immunoglobulin heavy locus	14q32.33	IGH@	3492	-
IGK locus	Immunoglobulin kappa locus	2p11.2	IGK@	50802	-
IGL locus	Immunoglobulin lambda locus	22q11.2	IGL@	3535	-

Portail to gene content in Gene tables

Genes of the human IG loci belong to ten groups:

• The human IGH locus at 14q32.33 comprises genes belonging to four groups: IGHV, IGHD, IGHJ and IGHC [1].
• The human IGK locus at 2p11.2 comprises genes belonging to three groups: IGKV, IGKJ and IGKC [1].
• The human IGL locus at 22q11.2 comprises genes belonging to three groups: IGLV, IGLJ and IGLC [1].

Number of genes per locus

• Total number of genes
• Number of functional genes

IMGT Posters

• IGH locus
• IGK locus
• IGL locus

Questions and answers (IMGT Education)

• Nomenclature and overview of the human immunoglobulin genes

IMGT reference:

[1]	Lefranc, M.-P. and Lefranc, G., The Immunoglobulin FactsBook, Academic Press, 458 pages (2001) ISBN:012441351X.

See also:

• @
• Chromosomal orphon set
• CLASSIFICATION
• Gene
• Group
• Locus
• Orphon

Created: 30/01/2001
Last updated: Tuesday, 29-Nov-2011 22:02:02 CET
Authors: Véronique Giudicelli and Marie-Paule Lefranc
Editors: Elodie Foulquier and Chantal Ginestoux
Contact: Marie-Paule Lefranc

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For any other use please contact Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr.

     

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