The orphons belong to 12 IG chromosomal orphon sets and to one TR chromosomal orphon set.
There are 76 identified orphons:
25 IGHV, 10 IGHD, 1 processed IGHC;
25 IGKV;
4 IGLV, 2 IGLC;
9 TRBV.
There is only one processed gene (IGHEP2) on chromosome 9, among the 76 identified orphons.
List of the IG orphons
List of the TR orphons
Orphon IMGT/LIGM-DB accession numbers are reported in Gene tables.
| Chromosome | Cytogenetic band | Group | Number of genes |
1 |
1pter-1qter | IGKV | 1 |
2 |
2p12 2cen-2q11 2q12-2q14 |
IGKV IGKV IGKV |
2 11 1 |
8 |
8q11.2 | IGLV | 2 |
9 |
9p24.2-p24.1 9p21 | IGHC TRBV | 1(1) 9 |
15 |
15 pter-15qter 15q11.2 |
IGKV IGHD IGHV |
1 10 9 |
16 |
16p11.2 | IGHV | 16 |
21 |
21p11.2 | IGHV | 1 |
22 |
22q12.2-22q12.3 22q11.2-22q12.1 22q12.2-22q12.3 22q11 |
IGLC IGLV IGLV IGKV |
2 1 1 5 |
N.L. |
IGKV | 4 | |
| Total | 77 orphons (including 1 processed gene) |
||
N.L. = not localized
IMGT notes:
References:
See also:
Created: 02/04/2001
Software material and data coming from IMGT server may be used for academic research only,
provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics
information system® http://www.imgt.org
(founder and director: Marie-Paule Lefranc, Montpellier, France)."
References to cite:
Lefranc, M.-P. et al.,
Nucleic Acids Research, 27, 209-212 (1999)
Cover of NAR;
Ruiz, M. et al.,
Nucleic Acids Research, 28, 219-221 (2000);
Lefranc, M.-P.,
Nucleic Acids Research, 29, 207-209 (2001);
Lefranc, M.-P.,
Nucleic Acids Res., 31, 307-310 (2003);
Lefranc, M.-P. et al.,
In Silico Biol., 5, 0006 (2004) [Epub],
5, 45-60 (2005);
Lefranc, M.-P. et al.,
Nucleic Acids Res., 33, D593-D597 (2005)
Full text;
Lefranc, M.-P. et al.,
Nucleic Acids Research 2009 37:
D1006-D1012; doi:10.1093/nar/gkn838
Full text.
(1) Corresponds to the processed gene IGHEP2.
[1] Lefranc, M.-P. and Lefranc, G., The Immunoglobulin FactsBook, Academic Press, 458 pages (2001) ISBN:012441351X.
[2] Lefranc, M.-P. and Lefranc, G., The T cell receptor FactsBook, Academic Press, 398 pages (2001) ISBN:0124413528.
Last updated: Wednesday, 29-Jun-2011 17:05:45 CEST
Authors: Véronique Giudicelli and Marie-Paule Lefranc
Marie-Paule.Lefranc@igh.cnrs.fr
Editors:
Elodie Foulquier and Chantal Ginestoux
Contact: Marie-Paule Lefranc
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IMGT founder and director: Marie-Paule Lefranc
Marie-Paule.Lefranc@igh.cnrs.fr
Bioinformatics manager: Véronique Giudicelli Veronique.Giudicelli@igh.cnrs.fr Computer manager: Patrice Duroux Patrice.Duroux@igh.cnrs.fr Webmaster: Chantal Ginestoux Chantal.Ginestoux@igh.cnrs.fr |
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