Alignment of alleles: Nurse shark (Ginglymostoma cirratum) IGHM1

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters.
Dashes indicate identical nucleotides. Dots indicate gaps by comparison to the longest sequence. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

The nucleotide between parentheses at the beginning of exons comes from a DONOR-SPLICE (n from ngt). The first nucleotide from an INT-DONOR-SPLICE is underlined (n from ngt).

Exon names are shown between parentheses on the first line.
The Cysteines involved in the IG CH1, CH2 and CH3 intrachain disulfide bridge are shown with a larger letter C in purple. The Cysteines involved in the H-L or H-H interchain disulfide bridge are shown with a larger letter C in black.
STOP-CODON is indicated by an asterisk.

N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown is green (site is underlined in CHS and in pages edited before 14/10/2009).

                                    1   2   3   4   5   6   7   8   9  10  11  12  13  14  15  16  17  18  19  20
                                   A   T   P   S   S   P   T   L   Y   G   L   V   S   S   C   Q   Q   G   N   I
  M92851  ,IGHM1*01, (CH1)(cDNA)(G)CA ACA CCG TCT TCT CCG ACA CTT TAT GGC TTA GTC TCC TCC TGT CAG CAA GGC AAC ATT

                                   21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40
                                   D   G   S   V   I   Y   G   C   L   A   M   D   Y   S   P   D   V   A   S   V
  M92851  ,IGHM1*01, (CH1) (cDNA) GAC GGT TCT GTG ATC TAT GGT TGC TTG GCG ATG GAC TAT TCC CCC GAC GTC GCC AGT GTG

                                   41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60
                                   T   W   K   K   H   G   Q   L   I   T   T   G   V   Q   T   Y   P   S   V   R
  M92851  ,IGHM1*01, (CH1) (cDNA) ACC TGG AAG AAA CAT GGG CAG CTG ATC ACG ACT GGA GTT CAG ACG TAC CCA TCG GTG AGA

                                   61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79  80
                                   N   K   K   G   T   Y   T   L   S   S   Q   L   A   L   I   E   S   D   A   E
  M92851  ,IGHM1*01, (CH1) (cDNA) AAC AAG AAA GGA ACT TAC ACG CTG AGC AGC CAG TTA GCC CTC ATC GAG TCA GAC GCG GAA

                                   81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 100
                                   C   D   Q   I   S   C   E   V   R   H   S   G   S   D   K   S   T   G   M   P
  M92851  ,IGHM1*01, (CH1) (cDNA) TGT GAC CAA ATA TCC TGT GAG GTT CGA CAC AGC GGG TCC GAC AAG AGC ACT GGA ATG CCA T



                                    1   2   3   4   5   6   7   8   9  10  11  12  13  14  15  16  17  18  19  20
                                   C   P   D   G   F   P   T   A   L   L   T   V   S   S   S   E   E   I   E   S
  M92851  ,IGHM1*01, (CH2)(cDNA)   GT CCT GAT GGC TTT CCG ACT GCT CTC CTA ACT GTA AGT TCC AGT GAA GAA ATC GAG AGC

                                   21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40
                                   R   K   F   A   I   I   V   C   S   I   S   D   F   H   S   K   S   I   S   V
  M92851  ,IGHM1*01, (CH2) (cDNA) AGA AAA TTT GCA ATC ATC GTC TGT TCA ATC AGT GAC TTC CAC TCA AAG TCA ATC TCC GTG

                                   41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60
                                   T   W   L   K   N   G   R   S   V   D   S   G   I   F   T   S   P   V   C   E
  M92851  ,IGHM1*01, (CH2) (cDNA) ACT TGG TTG AAG AAC GGA CGA AGC GTG GAT TCT GGC ATC TTC ACT TCT CCC GTG TGT GAA

                                   61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79  80
                                   A   N   G   N   F   S   V   T   S   R   L   R   V   P   Y   A   E   W   F   D
  M92851  ,IGHM1*01, (CH2) (cDNA) GCG AAT GGG AAC TTC TCA GTG ACC AGT CGC CTG AGA GTC CCT TAT GCT GAA TGG TTC GAC

                                   81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 100
                                   R   A   V   Y   T   C   Q   V   K   Y   K   E   V   I   Q   S   W   N   I   T 
  M92851  ,IGHM1*01, (CH2) (cDNA) AGA GCA GTC TAT ACA TGC CAG GTC AAG TAT AAA GAG GTC ATT CAA AGT TGG AAC ATC ACC

                                  101 102 103
                                   G   P   Q
  M92851  ,IGHM1*01, (CH2) (cDNA) GGA CCT CAG G




                                    1   2   3   4   5   6   7   8   9  10  11  12  13  14  15  16  17  18  19  20
                                   V   S   E   C   H   G   Y   T   A   K   I   L   P   P   P   V   E   Q   V   L
  M92851  ,IGHM1*01, (CH3)(cDNA)   TT TCC GAG TGC CAT GGT TAC ACA GCT AAA ATA CTA CCA CCA CCA GTC GAA CAG GTC TTA

                                   21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40
                                   L   E   A   T   V   T   L   T   C   V   V   S   N   L   H   S   G   V   N   F 
  M92851  ,IGHM1*01, (CH3) (cDNA) CTG GAG GCG ACA GTG ACA TTA ACC TGT GTT GTG TCC AAT CTT CAT TCT GGA GTC AAC TTC

                                   41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60
                                   T   W   L   Q   D   E   K   T   L   K   S   E   I   A   H   D   S   G   E   H
  M92851  ,IGHM1*01, (CH3) (cDNA) ACC TGG TTA CAA GAC GAG AAG ACT CTG AAA TCA GAG ATT GCT CAC GAC TCT GGA GAG CAT

                                   61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79  80
                                   S   D   G   A   I   S   K   L   D   I   S   T   E   A   W   L   S   E   V   V
  M92851  ,IGHM1*01, (CH3) (cDNA) TCC GAT GGT GCG ATC AGC AAA TTG GAT ATT TCT ACT GAA GCC TGG CTG AGT GAG GTT GTT

                                   81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 100
                                   F   E   C   V   V   N   H   Q   Y   L   P   T   P   L   R   D   S   I   H   K
  M92851  ,IGHM1*01, (CH3) (cDNA) TTC GAA TGC GTG GTG AAT CAT CAG TAT CTA CCG ACT CCT CTG AGA GAC TCC ATC CAC AAG

                                  101 102
                                   E   R
  M92851  ,IGHM1*01, (CH3) (cDNA) GAG AGA A




                                    1   2   3   4   5   6   7   8   9  10  11  12  13  14  15  16  17  18  19  20
                                   I   E   N   P   L   E   P   S   V   S   V   L   L   P   T   T   E   E   L   S
  M92851  ,IGHM1*01, (CH4)(cDNA)   TT GAA AAT CCA CTG GAG CCA TCG GTG TCT GTC CTC CTG CCA ACG ACA GAA GAA CTC TCC

                                   21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40
                                   A   Q   R   F   L   S   L   T   C   L   V   R   G   F   R   P   R   E   I   F
  M92851  ,IGHM1*01, (CH4) (cDNA) GCG CAG AGG TTT CTT TCC CTT ACC TGT TTA GTG AGA GGT TTC AGG CCC CGA GAG ATC TTT

                                   41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60
                                   V   K   W   T   T   N   D   K   P   V   N   P   S   N   Y   K   N   T   E   V
  M92851  ,IGHM1*01, (CH4) (cDNA) GTC AAG TGG ACA ACC AAC GAC AAG CCG GTT AAT CCC AGT AAC TAC AAG AAC ACC GAA GTG

                                   61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79  80
                                   T   A   E   S   D   N   T   S   F   F   L   Y   S   L   L   S   I   A   A   E
  M92851  ,IGHM1*01, (CH4) (cDNA) ACG GCA GAG AGC GAC AAC ACC TCC TTC TTC TTG TAC AGC CTG TTA TCC ATT GCA GCG GAG

                                   81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 100
                                   E   W   A   S   G   A   S   Y   S   C   V   V   G   H   E   A   I   P   L   K
  M92851  ,IGHM1*01, (CH4) (cDNA) GAG TGG GCC AGC GGT GCT TCT TAC TCC TGT GTG GTG GGA CAT GAA GCG ATT CCA TTG AAG

                                  101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120
                                   I   I   N   R   T   V   D   K   S   S   G   K   P   S   F   V   N   I   S   L
  M92851  ,IGHM1*01, (CH4) (cDNA) ATC ATC AAC AGA ACG GTT GAT AAA TCC AGC GGT AAA CCG AGT TTT GTG AAT ATT TCA CTT

                                  121 122 123 124 125 126 127 128 129 130
                                   A   L   M   D   T   I   N   S   C   Q   *
  M92851  ,IGHM1*01, (CH4) (cDNA) GCA CTG ATG GAC ACC ATT AAT TCA TGC CAA



This alignment of allele is automatically generated by Mehdi Yousfi alignment of allele tool.


Created: Wednesday, 29-Jun-2011 17:05:44 CEST
Author: Dominique Scaviner

Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Res., 27:209-212 (1999); doi: 10.1093/nar/27.1.209 Full text Cover; Ruiz, M. et al., Nucleic Acids Res., 28:219-221 (2000); doi: 10.1093/nar/28.1.219 Full text; Lefranc, M.-P., Nucleic Acids Res., 29:207-209 (2001); doi: 10.1093/nar/29.1.207 Full text; Lefranc, M.-P., Nucleic Acids Res., 31:307-310 (2003); doi: 10.1093/nar/gkg085 Full text; Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5:45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33:D593-597 (2005); doi: 10.1093/nar/gki065 Full text; Lefranc, M.-P. et al., Nucleic Acids Res., 37:D1006-1012 (2009); doi: 10.1093/nar/gkn838 Full text; Lefranc, M.-P. et al., Nucleic Acids Res., 43:D413-422 (2015); doi: 10.1093/nar/gku1056 Full text.
For any other use please contact Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr.

CNRS Université de Montpellier European Commission
IMGT® Founder and Executive Director Emeritus:
Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr
IMGT® Director:
Sofia Kossida Sofia.Kossida@igh.cnrs.fr
Bioinformatics manager:
Véronique Giudicelli Veronique.Giudicelli@igh.cnrs.fr
Computer manager:
Patrice Duroux Patrice.Duroux@igh.cnrs.fr
Webmaster:
Amélie Houles

Citing IMGT | Warranty disclaimer and copyright notice | Privacy policy and advertisement policy

© Copyright 1995-2017 IMGT®, the international ImMunoGeneTics information system®