Alignment of alleles: Nurse shark (Ginglymostoma cirratum) IGHN1

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters.
Dashes indicate identical nucleotides. Dots indicate gaps by comparison to the longest sequence. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

The nucleotide between parentheses at the beginning of exons comes from a DONOR-SPLICE (n from ngt). The first nucleotide from an INT-DONOR-SPLICE is underlined (n from ngt).

Exon names are shown between parentheses on the first line.
The Cysteines involved in the IG CH1, CH2 and CH3 intrachain disulfide bridge are shown with a larger letter C in purple. The Cysteines involved in the H-L or H-H interchain disulfide bridge are shown with a larger letter C in black.
STOP-CODON is indicated by an asterisk.

N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown is green (site is underlined in CHS and in pages edited before 14/10/2009).

                                      1   2   3   4   5   6   7   8   9  10  11  12  13  14  15  16  17  18  19  20
                                     G   I   P   P   S   P   P   I   V   S   L   L   H   S   A   T   E   E   Q   R
  U18701  ,IGHN1*01, (CH1) (cDNA) (G)GA ATA CCG CCT TCT CCA CCA ATA GTC AGT CTC CTC CAC TCT GCA ACT GAA GAA CAG AGA

                                     21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40
                                     A   N   R   F   V   Q   L   V   C   L   I   S   G   Y   Y   P   E   N   I   A
  U18701  ,IGHN1*01, (CH1) (cDNA)   GCA AAC AGA TTT GTG CAG CTG GTT TGT CTA ATC AGC GGA TAC TAT CCC GAA AAC ATT GCA

                                     41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60
                                     V   S   W   Q   K   N   T   K   T   I   T   S   G   F   A   T   T   S   P   V
  U18701  ,IGHN1*01, (CH1) (cDNA)   GTG AGC TGG CAG AAG AAC ACA AAG ACC ATA ACT TCT GGT TTT GCA ACA ACA TCC CCA GTG

                                     61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79  80
                                     K   T   S   S   N   D   F   S   C   A   S   L   L   K   V   P   L   Q   E   W
  U18701  ,IGHN1*01, (CH1) (cDNA)   AAA ACT TCG AGC AAT GAC TTC AGC TGT GCA AGT TTA CTT AAA GTG CCC CTA CAG GAA TGG

                                     81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 100
                                     S   R   G   S   V   Y   S   C   Q   V   S   H   S   A   T   S   S   N   Q   R
  U18701  ,IGHN1*01, (CH1) (cDNA)   AGC AGG GGT TCT GTG TAC AGT TGC CAA GTT TCT CAT TCT GCA ACC AGC AGT AAC CAG AGG

                                    101 102 103 104 105 106 107
                                     K   E   I   R   S   T   S
  U18701  ,IGHN1*01, (CH1) (cDNA)   AAA GAA ATT CGA TCA ACA TCC G



                                      1   2   3   4   5   6   7   8   9  10  11  12  13  14  15  16  17  18  19  20
                                     E   I   A   V   L   L   R   D   P   T   V   E   E   I   W   I   D   K   S   A
  U18701  ,IGHN1*01, (CH2) (cDNA)    AG ATC GCT GTA TTA CTG AGG GAT CCA ACA GTT GAA GAA ATC TGG ATC GAT AAA AGT GCC

                                     21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40
                                     T   L   V   C   E   V   L   S   T   V   S   A   G   V   V   V   S   W   M   V
  U18701  ,IGHN1*01, (CH2) (cDNA)   ACT CTA GTT TGC GAA GTG CTC TCC ACA GTT TCC GCT GGA GTA GTC GTC TCT TGG ATG GTA

                                     41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60
                                     N   G   K   V   R   N   E   G   V   Q   M   E   P   T   K   M   S   G   N   Q
  U18701  ,IGHN1*01, (CH2) (cDNA)   AAT GGA AAA GTA AGG AAT GAA GGC GTT CAA ATG GAA CCA ACT AAA ATG AGT GGA AAC CAA

                                     61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79  80
                                     Y   L   T   I   S   R   L   T   S   S   V   E   E   W   Q   S   G   V   E   Y
  U18701  ,IGHN1*01, (CH2) (cDNA)   TAT CTG ACA ATC AGC CGC TTG ACC AGC AGC GTG GAA GAG TGG CAG AGT GGG GTG GAA TAC

                                     81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 100
                                     T   C   S   A   K   Q   D   Q   S   S   T   P   V   V   K   R   T   R   K   A
  U18701  ,IGHN1*01, (CH2) (cDNA)   ACT TGC TCC GCA AAA CAG GAT CAA TCG TCC ACC CCA GTC GTA AAA CGA ACA CGA AAG GCA

                                    101
                                     R
  U18701  ,IGHN1*01, (CH2) (cDNA)   AGA G



                                      1   2   3   4   5   6   7   8   9  10  11  12  13  14  15  16  17  18  19  20
                                     V   E   P   T   K   P   H   L   R   L   L   P   P   S   P   E   E   I   Q   S
  U18701  ,IGHN1*01, (CH3) (cDNA)    TC GAA CCG ACA AAA CCA CAT CTC CGC CTC CTT CCC CCG TCA CCA GAA GAG ATT CAA AGC

                                     21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40
                                     T   S   S   A   T   L   T   C   L   I   R   G   F   Y   P   D   K   V   S   V
  U18701  ,IGHN1*01, (CH3) (cDNA)   ACC AGC TCT GCT ACT CTC ACA TGT TTG ATA AGA GGA TTC TAT CCT GAC AAA GTA AGC GTT

                                     41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60
                                     S   W   Q   K   D   D   V   S   V   S   A   N   V   T   N   F   P   T   A   L
  U18701  ,IGHN1*01, (CH3) (cDNA)   TCC TGG CAA AAA GAT GAT GTT TCT GTG AGC GCG AAC GTC ACC AAT TTC CCC ACT GCT CTG

                                     61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79  80
                                     E   Q   D   L   T   F   S   T   R   S   L   L   N   L   T   A   V   E   W   K
  U18701  ,IGHN1*01, (CH3) (cDNA)   GAA CAG GAC CTG ACC TTC AGC ACA CGG AGC CTC CTC AAT TTA ACT GCA GTG GAA TGG AAG

                                     81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 100
                                     S   G   A   K   Y   T   C   T   A   S   H   P   P   S   Q   S   T   V   K   R
  U18701  ,IGHN1*01, (CH3) (cDNA)   AGC GGA GCA AAA TAC ACT TGT ACT GCC TCA CAT CCA CCT TCA CAA TCC ACG GTG AAG AGG

                                    101 102 103 104 105
                                     V   I   R   N   Q
  U18701  ,IGHN1*01, (CH3) (cDNA)   GTC ATC AGG AAC CAG A



                                      1   2   3   4   5   6   7   8   9  10  11  12  13  14  15  16  17  18  19  20
                                     K   V   D   C   R   Q   T   D   I   S   V   S   L   L   K   P   P   F   E   E
  U18701  ,IGHN1*01, (CH4) (cDNA)    AA GTT GAT TGC CGT CAG ACA GAC ATT TCT GTC AGC CTA CTG AAG CCT CCG TTT GAA GAG

                                     21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40
                                     I   W   T   Q   Q   T   A   T   I   V   C   E   I   V   Y   S   D   L   E   N
  U18701  ,IGHN1*01, (CH4) (cDNA)   ATT TGG ACG CAA CAG ACA GCG ACC ATT GTT TGC GAA ATC GTT TAC AGC GAC TTA GAA AAC

                                     41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60
                                     I   K   V   F   W   Q   V   N   G   V   E   R   K   K   G   V   E   T   Q   N
  U18701  ,IGHN1*01, (CH4) (cDNA)   ATC AAA GTT TTC TGG CAA GTG AAT GGG GTT GAG AGA AAG AAA GGA GTC GAG ACG CAG AAT

                                     61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79  80
                                     P   E   W   S   G   S   K   S   T   I   V   S   K   L   K   V   M   A   S   E
  U18701  ,IGHN1*01, (CH4) (cDNA)   CCC GAG TGG AGC GGA AGT AAA TCC ACC ATT GTG AGC AAA CTC AAA GTC ATG GCG TCG GAG

                                     81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 100
                                     W   D   S   G   T   E   Y   V   C   L   V   E   D   S   E   L   P   T   P   V
  U18701  ,IGHN1*01, (CH4) (cDNA)   TGG GAC AGT GGT ACC GAA TAT GTT TGC TTG GTA GAA GAC AGT GAA TTG CCA ACA CCA GTG

                                    101 102 103 104 105 106 107 108 
                                     K   A   S   I   R   K   A   N   
  U18701  ,IGHN1*01, (CH4) (cDNA)   AAA GCC TCT ATC AGG AAG GCA AAT G



                                      1   2   3   4   5   6   7   8   9  10  11  12  13  14  15  16  17  18  19  20
                                     V   S   Q   M   H   P   P   K   V   Y   L   L   H   P   S   T   D   E   I   D   
  U18701  ,IGHN1*01, (CH5) (cDNA)    TC AGC CAA ATG CAT CCT CCC AAG GTT TAT CTC CTG CAT CCA TCG ACG GAC GAG ATT GAC 

                                     21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40
                                     T   E   N   S   A   T   L   M   C   L   A   T   N   F   H   P   A   E   I   Y   
  U18701  ,IGHN1*01, (CH5) (cDNA)   ACT GAG AAT TCG GCT ACC CTG ATG TGT CTA GCC ACC AAC TTT CAC CCA GCT GAG ATT TAC 

                                     41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60
                                     V   G   W   M   A   N   D   T   L   L   D   S   G   Y   R   T   Q   V   D   S   
  U18701  ,IGHN1*01, (CH5) (cDNA)   GTT GGT TGG ATG GCA AAT GAC ACT CTT TTG GAT TCT GGG TAC CGG ACC CAA GTA GAC AGC 

                                     61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79  80
                                     E   K   G   S   G   S   S   F   V   T   D   R   L   R   L   T   A   A   E   W   
  U18701  ,IGHN1*01, (CH5) (cDNA)   GAG AAG GGG AGT GGT TCC AGC TTC GTT ACC GAC AGA TTG AGA CTC ACA GCG GCT GAA TGG 

                                     81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 100
                                     N   S   D   T   T   Y   S   C   L   V   G   H   P   S   L   N   R   D   L   I   
  U18701  ,IGHN1*01, (CH5) (cDNA)   ACC AGT GAC ACC ACT TAC TCC TGC TTA GTG GGA CAT CCG TCC CTA AAC CGG GAT TTA ATC 

                                    101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120
                                     R   S   T   N   K   S   N   G   K   P   S   S   V   N   V   S   V   V   L   S   
  U18701  ,IGHN1*01, (CH5) (cDNA)   AGA AGT ACA AAT AAA TCT AAC GGT AAA CCG TCG TCA GTT AAT GTT TCA GTC GTA CTA AGC 

                                    121 122 123 124 125 126 127
                                     D   T   V   K   S   C   T   *
  U18701  ,IGHN1*01, (CH5) (cDNA)   GAC ACT GTT AAA TCC TGC ACA



This alignment of allele is automatically generated by Mehdi Yousfi alignment of allele tool.


Last updated: Monday, 11-Jul-2011 12:56:59 CEST
Created: 01/07/2002
Author: Dominique Scaviner

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