When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated
in red letters.
Dashes indicate identical nucleotides. Dots indicate gaps by comparison to the longest
sequence. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).
The nucleotide between parentheses at the beginning of exons comes from a DONOR-SPLICE (n from ngt). The first nucleotide from an INT-DONOR-SPLICE is underlined (n from ngt).
Exon names are shown between parentheses on the first line.
The Cysteines involved in the IG CH1, CH2 and CH3 intrachain disulfide bridge are shown with a larger letter C in purple.
The Cysteines involved in the H-L or H-H interchain disulfide bridge are shown with a larger letter C in black.
STOP-CODON is indicated by an asterisk.
N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown is green (site is underlined in CHS and in pages edited before 14/10/2009).
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
G I P L S P P I V S L L H S A T E E Q R
U18726 ,IGHN13*01, (CH1) (cDNA) (G)GA ATA CCG CTT TCT CCA CCA ATA GTC AGT CTC CTC CAC TCT GCA ACT GAA GAA CAG AGA
21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40
A N G F V Q L V C L I S G Y Y P E N I A
U18726 ,IGHN13*01, (CH1) (cDNA) GCA AAC GGA TTT GTG CAG CTG GTT TGT CTA ATC AGC GGA TAC TAT CCC GAA AAC ATT GCA
41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60
V S W Q K N T K T I T S G F A T T S P V
U18726 ,IGHN13*01, (CH1) (cDNA) GTG AGC TGG CAG AAG AAC ACA AAG ACC ATA ACT TCT GGT TTT GCA ACA ACA TCC CCA GTG
61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80
K T S S N D F S C A S L L K V P L Q E W
U18726 ,IGHN13*01, (CH1) (cDNA) AAA ACT TCG AGC AAT GAC TTC AGC TGT GCA AGT TTA CTT AAA GTG CCC CTA CAG GAA TGG
81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100
S R G S V Y S C Q V S H S A T S S N Q R
U18726 ,IGHN13*01, (CH1) (cDNA) AGC AGG GGT TCT GTG TAC AGT TGC CAA GTT TCT CAT TCT GCA ACC AGC AGT AAC CAG AGG
101 102 103 104 105 106 107
K E I R S T S
U18726 ,IGHN13*01, (CH1) (cDNA) AAA GAA ATT CGA TCA ACA TCC G
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
E I A V L L R D P T V E E I W I N K
U18726 ,IGHN13*01, (CH2) (cDNA) AG ATC GCT GTA TTA CTG AGG GAT CCA ACA GTT GAA GAA ATC TGG ATC AAT AAA
This alignment of allele is automatically generated by Mehdi Yousfi alignment of allele tool.
Created: 29/06/2011
Author: Dominique Scaviner
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References to cite:
Lefranc, M.-P. et al.,
Nucleic Acids Res., 27:209-212 (1999); doi: 10.1093/nar/27.1.209
Full text
Cover;
Ruiz, M. et al.,
Nucleic Acids Res., 28:219-221 (2000); doi: 10.1093/nar/28.1.219
Full text;
Lefranc, M.-P.,
Nucleic Acids Res., 29:207-209 (2001); doi: 10.1093/nar/29.1.207
Full text;
Lefranc, M.-P.,
Nucleic Acids Res., 31:307-310 (2003); doi: 10.1093/nar/gkg085
Full text;
Lefranc, M.-P. et al.,
In Silico Biol., 5, 0006 (2004) [Epub], 5:45-60 (2005);
Lefranc, M.-P. et al.,
Nucleic Acids Res., 33:D593-597 (2005); doi: 10.1093/nar/gki065
Full text;
Lefranc, M.-P. et al.,
Nucleic Acids Res., 37:D1006-1012 (2009); doi: 10.1093/nar/gkn838
Full text;
Lefranc, M.-P. et al.,
Nucleic Acids Res., 43:D413-422 (2015); doi: 10.1093/nar/gku1056
Full text.
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Marie-Paule.Lefranc@igh.cnrs.fr.
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