IMGT Web resources: IMGT repertoire

Alignment of alleles: Nurse shark (Ginglymostoma cirratum) IGHV2S6

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters.
Dashes indicate identical nucleotides. Dots indicate gaps by comparison to the longest sequence. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Alignments of alleles are provisory in the absence of the complete germline gene repertoire.

                            1   2   3   4   5   6   7   8   9  10  11  12  13  14  15  16  17  18  19  20 
                           A   R   V   D   Q   T   P   R   S       V   T   K   E   T   G   E   S   L   T  
  U18681  ,IGHV2S6*01     GCT CGA GTG GAC CAA ACA CCG AGA TCA ... GTA ACA AAG GAG ACG GGC GAA TCA CTG ACC 

                                                  ____________________CDR1-IMGT__________________
                           21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40 
                           I   N   C   V   L   R   D   S   S   Y   A   L   G   S                   T   C  
  U18681  ,IGHV2S6*01     ATC AAC TGT GTC CTA CGT GAT TCG AGT TAT GCA TTG GGG AGC ... ... ... ... ACG TGT 

                                                                                      ______________ CDR2-
                           41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60 
                           W   D   R   K   K   S   G   S   T       K   Y   V                              
  U18681  ,IGHV2S6*01     TGG GAT CGA AAA AAA TCG GGC AGC ACA ... AAA TAT GTT ... ... ... ... ... ... ... 

                          IMGT_______________
                           61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79  80 
                                                       G   I   V   M   G       G   R   Y   V   E   T   V  
  U18681  ,IGHV2S6*01     ... ... ... ... ... ... ... GGC ATA GTT ATG GGT ... GGC CGA TAT GTT GAA ACA GTT 


                           81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 100
                           N   S   G   S   K   S   F   S   L   R   I   N   D   L   T   V   E   D   G   G  
  U18681  ,IGHV2S6*01     AAC AGC GGA TCA AAG TCC TTT TCT TTG AGA ATT AAT GAT CTA ACA GTT GAA GAC GGT GGC 

                                          _CDR3-IMGT
                          101 102 103 104 105 106
                           T   Y   R   C   A   T  
  U18681  ,IGHV2S6*01     ACG TAT CGT TGC GCG ACT     #c

#c: rearranged cDNA

Created: 11/07/2011
Authors: Lorena Betancourt and Dominique Scaviner

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For any other use please contact Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr.

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