Alignment of alleles: Sandbar shark (Carcharhinus plumbeus) IGHV1S3

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters.
Dashes indicate identical nucleotides. Dots indicate gaps by comparison to the longest sequence. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Alignments of alleles are provisory in the absence of the complete germline gene repertoire.

                            1   2   3   4   5   6   7   8   9  10  11  12  13  14  15  16  17  18  19  20 
                           D   I   V   L   T   Q   P   E   G       V   V   K   K   P   G   E   T   V   R  
  U50605  ,IGHV1S3*01     GAT ATC GTG CTG ACC CAG CCC GAG GGG ... GTT GTG AAA AAG CCG GGG GAG ACA GTC AGA 

                                                   ____________________CDR1-IMGT__________________
                           21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40 
                           L   S   C   A   V   S   G   F   D   I   D   S   T   Y                   I   S  
  U50605  ,IGHV1S3*01     CTC TCC TGT GCA GTC AGT GGG TTC GAT ATC GAC AGC ACC TAC ... ... ... ... ATA AGT

                                                                                      _______________CDR2-
                           41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60 
                           W   V   K   Q   V   P   G   K   G   L   E   W   L   L   Y   H   D   S   K   P  
  U50605  ,IGHV1S3*01     TGG GTG AAG CAG GTC CCT GGC AAA GGG CTG GAG TGG TTA CTG TAC CAT GAT TCT AAA CCT 

                          IMGT_______________
                           61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79  80 
                           Q                   G   F   A   P   G   I   E       G   R   L   T   P   S   V  
  U50605  ,IGHV1S3*01     CAA ... ... ... ... GGG TTC GCG CCT GGA ATT GAA ... GGT CGA CTT ACC CCT TCT GTT 


                           81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 100 
                                   V   T   N   T   A   Y   I   E   I   T   S   L   R   V   D   D   T   A  
  U50605  ,IGHV1S3*01     ... ... GTC ACC AAC ACC GCT TAC ATA GAA ATC ACC AGT CTG AGA GTG GAT GAC ACC GCC
 
                                          _CDR3-IMGT_
                          101 102 103 104 105 106 
                           T   Y   Y   C   A   R  
  U50605  ,IGHV1S3*01     ACC TAT TAC TGT GCT AGA     #c

#c: rearranged cDNA


Created: 06/07/2000
Last updated: Monday, 11-Jul-2011 12:56:59 CEST
Authors: Lorena Betancourt and Dominique Scaviner

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