IMGT Web resources: IMGT repertoire

Alignment of alleles: Sandbar shark (Carcharhinus plumbeus) IGHV1S6

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters.
Dashes indicate identical nucleotides. Dots indicate gaps by comparison to the longest sequence. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Alignments of alleles are provisory in the absence of the complete germline gene repertoire.

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 D I V L T Q P E S V V K K P G E T V R U50608 ,IGHV1S6*01 GAT ATC GTG CTG ACC CAG CCC GAG TCT ... GTT GTG AAA AAG CCG GGG GAG ACA GTC AGA ____________________CDR1-IMGT__________________ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 L S C T V T G F E I D H T Y I S U50608 ,IGHV1S6*01 CTC TCC TGT ACA GTC ACT GGG TTC GAG ATC GAC CAT ACC TAC ... ... ... ... ATA AGT _______________CDR2- 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 W V K Q V P G K G L E W L L N H D I N P U50608 ,IGHV1S6*01 TGG GTG AAG CAG GTC CCT GGG AAA GGG CTG GAG TGG TTA CTG AAC CAT GAT ATA AAC CCT IMGT_______________ 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 Q N F A P G I E G R F T P S V U50608 ,IGHV1S6*01 CAA ... ... ... ... AAT TTC GCG CCT GGA ATT GAA ... GGT CGA TTT ACC CCG TCT GTA 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 I S N T A Y L E I T S L T T D D T A U50608 ,IGHV1S6*01 ... ... ATC AGC AAC ACC GCA TAC TTA GAA ATC ACC AGT CTG ACA ACG GAT GAC ACC GCC _CDR3-IMGT_ 101 102 103 104 105 106 I Y Y C T R U50608 ,IGHV1S6*01 ATC TAT TAC TGT ACT AGA #c

#c: rearranged cDNA

Created: 06/07/2000
Last updated: 11/07/2011
Authors: Lorena Betancourt and Dominique Scaviner

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