When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated
in red letters. These polymorphic mutations are reported in
Tables of alleles.
Dashes indicate identical nucleotides.
Dots indicate gaps by comparison to the longest
sequence. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Q V Q L Q Q W G A G L L K P S E T L S
AB019439,IGHV4-34*01 CAG GTG CAG CTA CAG CAG TGG GGC GCA ... GGA CTG TTG AAG CCT TCG GAG ACC CTG TCC
Z12363 ,IGHV4-34*01, DP-63 --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---
X56364 ,IGHV4-34*01, VH4.21 --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---
L10090 ,IGHV4-34*01, 4d76 --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---
Z75354 ,IGHV4-34*01, VH4-GL20
X92278 ,IGHV4-34*01, VH5 --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---
M99684 ,IGHV4-34*02, V4-34 --- --- --- --- --A --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---
X92255 ,IGHV4-34*03, VH4-MC5 --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---
X92257 ,IGHV4-34*03, VH4-MC5b --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---
X92236 ,IGHV4-34*04, 4.44 --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---
X92237 ,IGHV4-34*05, 4.44.3 --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---
X92256 ,IGHV4-34*06, VH4-MC5a --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---
X92258 ,IGHV4-34*07, VH4-MC5c --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---
M95113 ,IGHV4-34*08, H3 --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---
E S P V Q
Z14241 ,IGHV4-34*09, 4.36 --- --- --- --G --- G-- -C- --- C-- ... --- --- G-- --- --- --A C-- --- --- ---
E S P V
Z14242 ,IGHV4-34*10, 4.37 --- --- --- --G --- G-- -C- --- C-- ... --- --- G-- --- --- --- --- --- --- ---
X05716 ,IGHV4-34*11, V58 --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---
X56591 ,IGHV4-34*12, TouVH4.21 --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---
Z75356 ,IGHV4-34*13, VH4-GL4
___________________CDR1-IMGT____________________
21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40
L T C A V Y G G S F S G Y Y W S
AB019439,IGHV4-34*01 CTC ACC TGC GCT GTC TAT GGT GGG TCC TTC AGT GGT TAC TAC ... ... ... ... TGG AGC
Z12363 ,IGHV4-34*01, DP-63 --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- ---
X56364 ,IGHV4-34*01, VH4.21 --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- ---
L10090 ,IGHV4-34*01, 4d76 --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- ---
Z75354 ,IGHV4-34*01, VH4-GL20 --- --- --- --- --- --- --- --- --- ... ... ... ... --- ---
X92278 ,IGHV4-34*01, VH5 --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- ---
M99684 ,IGHV4-34*02, V4-34 --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- ---
X92255 ,IGHV4-34*03, VH4-MC5 --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- ---
X92257 ,IGHV4-34*03, VH4-MC5b --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- ---
X92236 ,IGHV4-34*04, 4.44 --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- ---
C
X92237 ,IGHV4-34*05, 4.44.3 --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- T--
X92256 ,IGHV4-34*06, VH4-MC5a --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- ---
X92258 ,IGHV4-34*07, VH4-MC5c --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- ---
T
M95113 ,IGHV4-34*08, H3 --- --- --- --- --- --- --- --- A-- --- --- --- --- --- ... ... ... ... --- ---
Z14241 ,IGHV4-34*09, 4.36 --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- ---
Z14242 ,IGHV4-34*10, 4.37 --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- ---
V
X05716 ,IGHV4-34*11, V58 --- --- --- --- --- --- --- --- --- G-- --- --- --- --- ... ... ... ... --- ---
X56591 ,IGHV4-34*12, TouVH4.21 --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- ---
Z75356 ,IGHV4-34*13, VH4-GL4 --- --- --- --- --- --- --- --- --- ... ... ... ... --- ---
_______________CDR2-
41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60
W I R Q P P G K G L E W I G E I N H S G
AB019439,IGHV4-34*01 TGG ATC CGC CAG CCC CCA GGG AAG GGG CTG GAG TGG ATT GGG GAA ATC AAT CAT AGT GGA
Z12363 ,IGHV4-34*01, DP-63 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X56364 ,IGHV4-34*01, VH4.21 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
L10090 ,IGHV4-34*01, 4d76 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
Z75354 ,IGHV4-34*01, VH4-GL20 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X92278 ,IGHV4-34*01, VH5 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
M99684 ,IGHV4-34*02, V4-34 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X92255 ,IGHV4-34*03, VH4-MC5 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X92257 ,IGHV4-34*03, VH4-MC5b --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X92236 ,IGHV4-34*04, 4.44 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
L
X92237 ,IGHV4-34*05, 4.44.3 --- --- --- --- --- -T- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X92256 ,IGHV4-34*06, VH4-MC5a --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X92258 ,IGHV4-34*07, VH4-MC5c --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --C --- --- ---
M95113 ,IGHV4-34*08, H3 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
Z14241 ,IGHV4-34*09, 4.36 --- --- --- --- --- --- --- --- --A --- --- --- --- --- --- --- --- --- --- ---
Z14242 ,IGHV4-34*10, 4.37 --- --- --- --- --- --- --- --- --A --- --- --- --- --- --- --- --- --- --- ---
Y Y Y
X05716 ,IGHV4-34*11, V58 --- --- --G --- --- --- --- --- --- --- --- --- --- --- T-T --- T-- T-- --- --G
I
X56591 ,IGHV4-34*12, TouVH4.21 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -T- --- --- ---
Z75356 ,IGHV4-34*13, VH4-GL4 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
IMGT________________
61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80
S T N Y N P S L K S R V T I S V
AB019439,IGHV4-34*01 AGC ACC ... ... ... AAC TAC AAC CCG TCC CTC AAG ... AGT CGA GTC ACC ATA TCA GTA
Z12363 ,IGHV4-34*01, DP-63 --- --- ... ... ... --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---
X56364 ,IGHV4-34*01, VH4.21 --- --- ... ... ... --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---
L10090 ,IGHV4-34*01, 4d76 --- --- ... ... ... --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---
Z75354 ,IGHV4-34*01, VH4-GL20 --- --- ... ... ... --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---
X92278 ,IGHV4-34*01, VH5 --- --- ... ... ... --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---
M99684 ,IGHV4-34*02, V4-34 --- --- ... ... ... --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---
X92255 ,IGHV4-34*03, VH4-MC5 --- --- ... ... ... --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---
X92257 ,IGHV4-34*03, VH4-MC5b --- --- ... ... ... --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---
N A
X92236 ,IGHV4-34*04, 4.44 --- --- ... ... ... --- A-- --- --- --- --- --- ... --- --- -C- --- --- --- ---
N A
X92237 ,IGHV4-34*05, 4.44.3 --- --- ... ... ... --- A-- --- --- --- --- --- ... --- --- -C- --- --- --- ---
X92256 ,IGHV4-34*06, VH4-MC5a --- --- ... ... ... --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---
X92258 ,IGHV4-34*07, VH4-MC5c --- --- ... ... ... --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---
M95113 ,IGHV4-34*08, H3 --- --- ... ... ... --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---
Z14241 ,IGHV4-34*09, 4.36 --- --- ... ... ... --- --- --- --- --- --- --- ... --- --- --T --- --- --- ---
I M
Z14242 ,IGHV4-34*10, 4.37 --- --- ... ... ... --- --- --- --- --- --- --- ... --- --- A-- --- --G --- ---
N A
X05716 ,IGHV4-34*11, V58 --- --- ... ... ... --- A-- --- --C --- --- --- ... --- --- -C- --- --- --- ---
X56591 ,IGHV4-34*12, TouVH4.21 --- --- ... ... ... --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---
Z75356 ,IGHV4-34*13, VH4-GL4 --- --- ... ... ... --- --- --- --C --- --- --- ... --- --- --- --- --- --- ---
81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100
D T S K N Q F S L K L S S V T A A D T A
AB019439,IGHV4-34*01 GAC ACG TCC AAG AAC CAG TTC TCC CTG AAG CTG AGC TCT GTG ACC GCC GCG GAC ACG GCT
Z12363 ,IGHV4-34*01, DP-63 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X56364 ,IGHV4-34*01, VH4.21 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
L10090 ,IGHV4-34*01, 4d76 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
Z75354 ,IGHV4-34*01, VH4-GL20 --- --- ---
X92278 ,IGHV4-34*01, VH5 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
M99684 ,IGHV4-34*02, V4-34 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X92255 ,IGHV4-34*03, VH4-MC5 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --C
X92257 ,IGHV4-34*03, VH4-MC5b --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --C
X92236 ,IGHV4-34*04, 4.44 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X92237 ,IGHV4-34*05, 4.44.3 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
G
X92256 ,IGHV4-34*06, VH4-MC5a --- --- --- --- --- --- --- --- --- --- --- G-- --- --- --- --- --- --- --- --C
X92258 ,IGHV4-34*07, VH4-MC5c --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --C
M95113 ,IGHV4-34*08, H3 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
Z14241 ,IGHV4-34*09, 4.36 --- --- --T --- --- --- --- --- --- --- --- --- --- --- --T --- --- --- --- --C
Y
Z14242 ,IGHV4-34*10, 4.37 --- --- --- --- --- --- --- -A- --- --- --- --- --- --- --- --- --- --- --- --C
N
X05716 ,IGHV4-34*11, V58 --- --- --- --- --- --- --- --- --- --C --- --- --- --- --- --- --- --- --- --C
X56591 ,IGHV4-34*12, TouVH4.21 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
Z75356 ,IGHV4-34*13, VH4-GL4 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
_CDR3-IMGT__
101 102 103 104 105 106
V Y Y C A R
AB019439,IGHV4-34*01 GTG TAT TAC TGT GCG AGA GG
Z12363 ,IGHV4-34*01, DP-63 --- --- --- --- --- ---
X56364 ,IGHV4-34*01, VH4.21 --- --- --- --- --- ---
L10090 ,IGHV4-34*01, 4d76 --- --- --- --- --- --- --
X92278 ,IGHV4-34*01, VH5 --- --- --- --- --- --- --
M99684 ,IGHV4-34*02, V4-34 --- --- --- --- --- --- --
X92255 ,IGHV4-34*03, VH4-MC5 --- --- --- --
X92257 ,IGHV4-34*03, VH4-MC5b --- --- --- --
X92236 ,IGHV4-34*04, 4.44 --- --- --- --- --- --- --
X92237 ,IGHV4-34*05, 4.44.3 --- --- --- --- --- --- --
X92256 ,IGHV4-34*06, VH4-MC5a --- --- --- --
X92258 ,IGHV4-34*07, VH4-MC5c --- --- --- --
M95113 ,IGHV4-34*08, H3 --- --- --- --- ---
Z14241 ,IGHV4-34*09, 4.36 --- --- --- --- --- ---
Z14242 ,IGHV4-34*10, 4.37 --- --- --- --- --- ---
C
X05716 ,IGHV4-34*11, V58 --- --- -G- --- --- ---
X56591 ,IGHV4-34*12, TouVH4.21 --- --- --- --- --- ---
Z75356 ,IGHV4-34*13, VH4-GL4 --- --- --- --- --- --- --
This alignment of allele is automatically generated by Mehdi Yousfi alignment of allele tool.
Created: 07/08/1997
Last updated: Monday, 11-Jul-2011 12:56:52 CEST
Authors: Dominique Scaviner, Nathalie Pallarès
Contact: Marie-Paule Lefranc
Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Research, 27, 209-212 (1999) Cover of NAR; Ruiz, M. et al., Nucleic Acids Research, 28, 219-221 (2000); Lefranc, M.-P., Nucleic Acids Research, 29, 207-209 (2001); Lefranc, M.-P., Nucleic Acids Res., 31, 307-310 (2003); Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5, 45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33, D593-D597 (2005) Full text; Lefranc, M.-P. et al., Nucleic Acids Research 2009 37: D1006-D1012; doi:10.1093/nar/gkn838 Full text.
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Marie-Paule.Lefranc@igh.cnrs.fr
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