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When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

                                                                                                                          
                                  
                                  1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                   X   S   E   T   S   P   S   I   F   P   L   S   L   G   N   N 
  KT723008 IGHA*01 F CH1 gDNA                     nag agt gaa acc agc ccc agc atc ttc ccg ctg agc ctt ggg aac aac
                             
                                                                                                                 
  AF109167 IGHA*01 F CH1 gDNA                      -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                             


                                              _____AB_____                                            ____________
                                              15.1    15.3                                                        
                                   13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                   D   P                   A   G   Q   V   V   I   G   C   L   V   Q   G   F   F 
  KT723008 IGHA*01 F CH1 gDNA     gac cca ... ... ... ... gcc ggg cag gtg gtc atc ggc tgc ctg gtc cag ggc ttc ttc
                             
                                                                                                                 
  AF109167 IGHA*01 F CH1 gDNA     --- --- ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                             


                                  _______BC___________________                            _____________CD_________
                                                                                          45.1    45.3    45.5    
                                   30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                   P   S       A   P   L   S   V   T   W   N   Q   N   G   D   S   V             
  KT723008 IGHA*01 F CH1 gDNA     ccg tcg ... gca ccc ctg agc gtg acc tgg aac cag aat ggc gac agc gtg ... ... ...
                             
                                                                                                                 
  AF109167 IGHA*01 F CH1 gDNA     --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ...
                             


                                  ____                                ___________________________DE_______________
                                  45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                       77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                       S   V   R   N   F   P   A   V   L   A   G   S                             
  KT723008 IGHA*01 F CH1 gDNA     ... tcc gtc agg aac ttc cct gcc gtg ctg gcc ggg agc ... ... ... ... ... ... ...
                             
                                                                                                                 
  AF109167 IGHA*01 F CH1 gDNA     ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ...
                             


                                  ____________                                                ___EF___            
                                      85.2                                                    96.1                
                                  85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                   L   Y   T   M   S   S   Q   L   T   L   P   A   S   L   C           P   K   G 
  KT723008 IGHA*01 F CH1 gDNA     ctg tac acc atg agc agc cag ctg acc ttg ccg gcc agc ctg tgc ... ... cca aaa ggc
                             
                                                                                                                 
  AF109167 IGHA*01 F CH1 gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---
                             


                                                      _________________________FG_________________________        
                                  
                                  100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                   Q   S   V   T   C   Q   V   Q   H   L               S   K   A   S   K   T   V 
  KT723008 IGHA*01 F CH1 gDNA     cag tcc gtg acc tgc caa gtg cag cac ctc ... ... ... tcc aaa gcc agc aag acc gtg
                             
                                                                                                                 
  AF109167 IGHA*01 F CH1 gDNA     --- --- --- --- --- --- --- --- --- --- ... ... ... --- --- --- --- --- --- ---
                             


                                                              
                                  
                                  120 121 122 123 124 125 126 
                                   A   V   P   C   I   I   Q  
  KT723008 IGHA*01 F CH1 gDNA     gcc gtg ccc tgc ata att caa 
                             
                                                              
  AF109167 IGHA*01 F CH1 gDNA     --- --- --- --- --- --- --- 
                             










                                
                                
                                 1   2   3   4   5   6   7   8  
                                 D   S   S   S   C   C   V   P  
  KT723008 IGHA*01 F H gDNA     gac tca agt tca tgt tgc gtg ccg 
                           
                                                                
  AF109167 IGHA*01 F H gDNA      -- --- --- --- --- --- --- --- 
                           










                                                                                                                  
                                  
                                  1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                           N   C   E   P   S   L   S   V   Q   P   P   A   L   E 
  KT723008 IGHA*01 F CH2 gDNA                             aac tgc gag ccc agc ctg tcc gtg cag cca cca gcc ctc gag
                             
                                                                                                                 
  AF109167 IGHA*01 F CH2 gDNA                             --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                             


                                              _____AB_____                                            ____________
                                              15.1    15.3                                                        
                                   13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                   D   L   L   L           G   S   N   A   S   L   T   C   T   L   S   G   L   K 
  KT723008 IGHA*01 F CH2 gDNA     gac ctg ctc ctg ... ... ggc tcc aac gcc agc ctc acg tgc aca ctg agt ggc ctg aaa
                             
                                                                                                                 
  AF109167 IGHA*01 F CH2 gDNA     --- --- --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                             


                                  _______BC___________________                            _____________CD_________
                                                                                          45.1    45.3    45.5    
                                   30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                   S   A       E   G   A   S   F   T   W   N   P   T   G   G   K   T             
  KT723008 IGHA*01 F CH2 gDNA     agc gcc ... gag ggc gcc agc ttc acc tgg aac ccg aca ggt ggg aag acc ... ... ...
                             
                                                                                                                 
  AF109167 IGHA*01 F CH2 gDNA     --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ...
                             


                                  ____                                ___________________________DE_______________
                                  45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                       77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                           A   V   Q   G   S   P   K   R   D   S   C   G                         
  KT723008 IGHA*01 F CH2 gDNA     ... ... gcc gtc cag ggg tcg ccc aag cgt gac tcc tgt ggc ... ... ... ... ... ...
                             
                                                                                                                 
  AF109167 IGHA*01 F CH2 gDNA     ... ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ...
                             


                                  ____________                                                ___EF___            
                                      85.2                                                    96.1                
                                  85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                   C   Y   S   V   S   S   V   L   P   G   C   A   D   P   W           N   S   G 
  KT723008 IGHA*01 F CH2 gDNA     tgc tac agc gtg tcc agc gtc ctg ccg ggc tgt gcc gat ccc tgg ... ... aac agt gga
                             
                                                                                                                 
  AF109167 IGHA*01 F CH2 gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---
                             


                                                      _________________________FG_________________________        
                                  
                                  100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                   Q   T   F   S   C   S   V   T   H   P   E           S   K   S   S   L   T   A 
  KT723008 IGHA*01 F CH2 gDNA     cag act ttc tcc tgc tct gtc acc cac ccc gag ... ... tcc aag agt tca ctg acc gcc
                             
                                                                                                                 
  AF109167 IGHA*01 F CH2 gDNA     --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- --- ---
                             


                                                          
                                  
                                  120 121 122 123 124 125 
                                   T   I   K   K   D   L  
  KT723008 IGHA*01 F CH2 gDNA     acc atc aag aaa gac tta 
                             
                                                          
  AF109167 IGHA*01 F CH2 gDNA     --- --- --- --- --- --- 
                             










                                                                                                                      
                                      
                                      1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                       G   N   T   F   R   P   Q   V   H   L   L   P   P   P   S   E 
  KT723008 IGHA*01 F CH3-CHS gDNA                     ggg aac acg ttc cgg cct cag gtc cac ctg ctg ccg ccg ccg tcg gag
                                 
                                                                                                                     
  AF109167 IGHA*01 F CH3-CHS gDNA                      -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                 


                                                  _____AB_____                                            ____________
                                                  15.1    15.3                                                        
                                       13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                       E   L   A   L           N   E   L   V   T   L   T   C   L   V   R   G   F   S 
  KT723008 IGHA*01 F CH3-CHS gDNA     gag ctg gcc ctc ... ... aac gag ctg gtg acg ctg acg tgc ctg gtg cgg gga ttc agc
                                 
                                                                                                                     
  AF109167 IGHA*01 F CH3-CHS gDNA     --- --- --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                 


                                      _______BC___________________                            _____________CD_________
                                                                                              45.1    45.3    45.5    
                                       30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                       P           K   E   V   L   V   R   W   L   Q   G   N   Q   E   L   P   R   E 
  KT723008 IGHA*01 F CH3-CHS gDNA     ccc ... ... aag gag gtg ctg gtg cgt tgg ctg cag ggc aat caa gag ctg ccc cgc gag
                                 
                                                                                                                     
  AF109167 IGHA*01 F CH3-CHS gDNA     --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                 


                                      ____                                ___________________________DE_______________
                                      45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                           77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                           K   Y   L   T   W   G   P   L   P   E   A   G   Q   S               V   T 
  KT723008 IGHA*01 F CH3-CHS gDNA     ... aag tat ctg acc tgg ggc ccc ctg ccc gag gct ggc cag agc ... ... ... gtc acc
                                 
                                                                                                                     
  AF109167 IGHA*01 F CH3-CHS gDNA     ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... --- ---
                                 


                                      ____________                                                ___EF___            
                                          85.2                                                    96.1                
                                      85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                       T   F   A   V   T   S   V   L   R   V   D   A   E   V   W           K   Q   G 
  KT723008 IGHA*01 F CH3-CHS gDNA     acc ttc gcc gtg acc agc gtg cta cgc gtg gac gcc gag gtc tgg ... ... aag cag ggg
                                 
                                                                                                                     
  AF109167 IGHA*01 F CH3-CHS gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---
                                 


                                                          _________________________FG_________________________        
                                      
                                      100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                       D   T   F   S   C   M   V   G   H   E   A       L   P   L   A   F   T   Q   K 
  KT723008 IGHA*01 F CH3-CHS gDNA     gac acc ttc tcc tgc atg gtg ggc cac gag gcc ... ctg ccc ctg gcc ttc acc cag aag
                                 
                                                                                                                     
  AF109167 IGHA*01 F CH3-CHS gDNA     --- --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- ---
                                 


                                                                          ______________________________________CHS___
                                      
                                      120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 
                                       T   I   D   R   L   A               G   K   P   T   H   V   N   V   S   V   V 
  KT723008 IGHA*01 F CH3-CHS gDNA     acc atc gac cgc ctg gcg ... ... ... ggt aaa ccc acc cac gtg aac gtg tcc gtg gtc
                                 
                                                                                                                     
  AF109167 IGHA*01 F CH3-CHS gDNA     --- --- --- --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- ---
                                 


                                      ____________________________________
                                      
                                      140 141 142 143 144 145 146 147 148 
                                       M   S   E   V   D   G   V   C   Y  
  KT723008 IGHA*01 F CH3-CHS gDNA     atg tca gag gtg gat ggg gtc tgc tac 
                                 
                                                                          
  AF109167 IGHA*01 F CH3-CHS gDNA     --- --- --- --- --- --- --- --- --- 
                                 










                                
                                
                                 1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                 E   H   Q   P   W   L   V   L   D   L   M   Q   S   S   P   E   E   D   S   P 
  KT723008 IGHA*01 F M gDNA     gaa cat cag ccc tgg ctg gtg ctg gac ctg atg cag agc agc ccc gag gag gac agc cca
                           


                                
                                
                                 21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40 
                                 E   A   S   L   W   P   T   T   V   T   L   L   T   L   F   L   L   S   L   F 
  KT723008 IGHA*01 F M gDNA     gag gcc agc ctg tgg ccc acg acc gtc acc ctg ctc acc ctc ttc ctg ctg agc ctc ttc
                           


                                
                                
                                 41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60 
                                 Y   S   T   A   L   T   V   T   S   I   R   T   T   P   D   S   R   E   V   P 
  KT723008 IGHA*01 F M gDNA     tac agc aca gca ctg act gtg acg agc atc cgg acc acg ccg gac agc cgg gag gtc ccc
                           


                                
                                
                                 61  62 
                                 Q   Y  
  KT723008 IGHA*01 F M gDNA     cag tac 

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
07/11/2017
Authors:
Perrine Pégorier