Here you are: IMGT Web resources > IMGT Repertoire > Proteins and alleles

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

                                                                                                                             
                                     
                                     1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                      X   S   T   T   A   P   K   V   Y   P   L   S   S   C   C   G 
  X16701   IGHG1*01 F   CH1 gDNA                     ncc tcc acc aca gcc ccg aaa gtc tac cct ctg agt tct tgc tgc ggg
                                
                                                      A                                                             
  X62916   IGHG1*02 (F) CH1 cDNA                     g-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                
                                                      A                                                             
  S82409   IGHG1*03 (F) CH1 cDNA                     g-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                
                                                                                                                    
  KT723008 IGHG1*04 F   CH1 gDNA                     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                


                                                 _____AB_____                                            ____________
                                                 15.1    15.3                                                        
                                      13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                      D   K   S               S   S   T   V   T   L   G   C   L   V   S   S   Y   M 
  X16701   IGHG1*01 F   CH1 gDNA     gac aag tcc ... ... ... agc tcc acc gtg acc ctg ggc tgc ctg gtc tcc agc tac atg
                                
                                                                                                                    
  X62916   IGHG1*02 (F) CH1 cDNA     --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                
                                                                                                                    
  S82409   IGHG1*03 (F) CH1 cDNA     --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                
                                                                                                                    
  KT723008 IGHG1*04 F   CH1 gDNA     --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                


                                     _______BC___________________                            _____________CD_________
                                                                                             45.1    45.3    45.5    
                                      30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                      P           E   P   V   T   V   T   W   N   S   G   A   L   K   S             
  X16701   IGHG1*01 F   CH1 gDNA     ccc ... ... gag ccg gtg acc gtg acc tgg aac tcg ggt gcc ctg aag agc ... ... ...
                                
                                                                                                                    
  X62916   IGHG1*02 (F) CH1 cDNA     --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ...
                                
                                                                                                                    
  S82409   IGHG1*03 (F) CH1 cDNA     --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ...
                                
                                                                                                                    
  KT723008 IGHG1*04 F   CH1 gDNA     --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ...
                                


                                     ____                                ___________________________DE_______________
                                     45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                          77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                          G   V   H   T   F   P   A   V   L   Q   S   S                           G 
  X16701   IGHG1*01 F   CH1 gDNA     ... ggc gtg cac acc ttc ccg gcc gtc ctt cag tcc tcc ... ... ... ... ... ... ggg
                                
                                                                                                                    
  X62916   IGHG1*02 (F) CH1 cDNA     ... --- --- --- --- --- --- --t --- --- --- --- --- ... ... ... ... ... ... ---
                                
                                                                                                                    
  S82409   IGHG1*03 (F) CH1 cDNA     ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---
                                
                                                                                                                    
  KT723008 IGHG1*04 F   CH1 gDNA     ... --- --- --- --- --- --- --t --- --- --- --- --- ... ... ... ... ... ... ---
                                


                                     ____________                                                ___EF___            
                                         85.2                                                    96.1                
                                     85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                      L   Y   S   L   S   S   M   V   T   V   P   G   S   T   S               G     
  X16701   IGHG1*01 F   CH1 gDNA     ctg tac tct ctc agc agc atg gtg acc gtg ccc ggc agc acc tca ... ... ... gga ...
                                
                                                                                                                    
  X62916   IGHG1*02 (F) CH1 cDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... --- ...
                                
                                                                                                                  T 
  S82409   IGHG1*03 (F) CH1 cDNA     --c --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... --- acc
                                
                                                                                          S                         
  KT723008 IGHG1*04 F   CH1 gDNA     --c --- --- --- --- --- --- --- --- --- --- --- --- -g- --- ... ... ... --- ...
                                


                                                         _________________________FG_________________________        
                                     
                                     100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                      Q   T   F   T   C   N   V   A   H   P   A           S   S   T   K   V   D   K 
  X16701   IGHG1*01 F   CH1 gDNA     cag acc ttc acc tgc aac gta gcc cac ccg gcc ... ... agc agc acc aag gtg gac aag
                                
                                                                                                                    
  X62916   IGHG1*02 (F) CH1 cDNA     --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- --- ---
                                
                                                                                                                    
  S82409   IGHG1*03 (F) CH1 cDNA     --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- --- ---
                                
                                                                                                                    
  KT723008 IGHG1*04 F   CH1 gDNA     --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- --- ---
                                


                                             
                                     
                                     120 121 
                                      A   V  
  X16701   IGHG1*01 F   CH1 gDNA     gct gtt 
                                
                                             
  X62916   IGHG1*02 (F) CH1 cDNA     --- --- 
                                
                                             
  S82409   IGHG1*03 (F) CH1 cDNA     --- --- 
                                
                                             
  KT723008 IGHG1*04 F   CH1 gDNA     --- --- 
                                










                                   
                                   
                                    1   2   3   4   5   6   7   8   9   10  11  12  13 
                                    D   P   T   C   K   P   S   P   C   D   C   C   P  
  X16701   IGHG1*01 F   H gDNA     gat ccc aca tgc aaa cca tca ccc tgt gac tgt tgc cca 
                              
                                                                                       
  X62916   IGHG1*02 (F) H cDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- 
                              
                                            R               T   T                      
  S82409   IGHG1*03 (F) H cDNA     --- --- -g- --- --- ... a-- a-- --- --- --- --- --- 
                              
                                            R               T   T                      
  KT723008 IGHG1*04 F   H gDNA     --- --- -g- --- --- ... a-- a-- --- --- --- --- --- 
                              










                                                                                                                     
                                     
                                     1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                              P   P   E   L   P   G   G   P   S   V   F   I   F   P   P   K   P   K 
  X16701   IGHG1*01 F   CH2 gDNA             ccc cct gag ctc ccc gga gga ccc tct gtc ttc atc ttc cca ccg aaa ccc aag
                                
                                                                                                                    
  X62916   IGHG1*02 (F) CH2 cDNA             --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                
                                                                                                                    
  S82409   IGHG1*03 (F) CH2 cDNA             --g --- --- --- --t --- --- --- --- --- --- --- --- --- --- --- --- ---
                                
                                                                                                                    
  KT723008 IGHG1*04 F   CH2 gDNA             --g --- --- --- --t --- --- --- --- --- --- --- --- --- --- --- --- ---
                                


                                                 _____AB_____                                            ____________
                                                 15.1    15.3                                                        
                                      13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                      D   T   L   T   I       S   G   T   P   E   V   T   C   V   V   V   D   V   G 
  X16701   IGHG1*01 F   CH2 gDNA     gac acc ctc aca atc ... tcg gga acg ccc gag gtc acg tgt gtg gtg gtg gac gtg ggc
                                
                                                                                                                    
  X62916   IGHG1*02 (F) CH2 cDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                
                                                                                                                    
  S82409   IGHG1*03 (F) CH2 cDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                
                                                                                                                    
  KT723008 IGHG1*04 F   CH2 gDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                


                                     _______BC___________________                            _____________CD_________
                                                                                             45.1    45.3    45.5    
                                      30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                      H   D   D   P   E   V   K   F   S   W   F   V   D   D   V   E   V   N         
  X16701   IGHG1*01 F   CH2 gDNA     cac gat gac ccc gag gtg aag ttc tcc tgg ttc gtg gac gac gtg gag gta aac ... ...
                                
                                                                                                                    
  X62916   IGHG1*02 (F) CH2 cDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ...
                                
                                                                                                                    
  S82409   IGHG1*03 (F) CH2 cDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ...
                                
                                                                                                                    
  KT723008 IGHG1*04 F   CH2 gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ...
                                


                                     ____                                ___________________________DE_______________
                                     45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                          77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                          T   A   T   T   K   P   R   E   E   Q   F   N                           S 
  X16701   IGHG1*01 F   CH2 gDNA     ... aca gcc acg acg aag ccg aga gag gag cag ttc aac ... ... ... ... ... ... agc
                                
                                                                                                                    
  X62916   IGHG1*02 (F) CH2 cDNA     ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---
                                
                                                                                                                    
  S82409   IGHG1*03 (F) CH2 cDNA     ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---
                                
                                                                                                                    
  KT723008 IGHG1*04 F   CH2 gDNA     ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---
                                


                                     ____________                                                ___EF___            
                                         85.2                                                    96.1                
                                     85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                      T   Y   R   V   V   S   A   L   R   I   Q   H   Q   D   W           T   G   G 
  X16701   IGHG1*01 F   CH2 gDNA     acc tac cgc gtg gtc agc gcc ctg cgc atc cag cac cag gac tgg ... ... act gga gga
                                
                                                                                                                    
  X62916   IGHG1*02 (F) CH2 cDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---
                                
                                                                                                                    
  S82409   IGHG1*03 (F) CH2 cDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---
                                
                                                                                                                    
  KT723008 IGHG1*04 F   CH2 gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---
                                


                                                         _________________________FG_________________________        
                                     
                                     100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                      K   E   F   K   C   K   V   H   N   E   G           L   P   A   P   I   V   R 
  X16701   IGHG1*01 F   CH2 gDNA     aag gag ttc aag tgc aag gtc cac aac gaa ggc ... ... ctc ccg gcc ccc atc gtg agg
                                
                                                                                                                    
  X62916   IGHG1*02 (F) CH2 cDNA     --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- --- ---
                                
                                                                                                                    
  S82409   IGHG1*03 (F) CH2 cDNA     --- --- --- --- --- --- --- --- --- --- --- ... ... --- --a --- --- --- --- ---
                                
                                                                                                                    
  KT723008 IGHG1*04 F   CH2 gDNA     --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- --- ---
                                


                                                             
                                     
                                     120 121 122 123 124 125 
                                      T   I   S   R   T   K  
  X16701   IGHG1*01 F   CH2 gDNA     acc atc tcc agg acc aaa 
                                
                                                             
  X62916   IGHG1*02 (F) CH2 cDNA     --- --- --- --- --- --- 
                                
                                                             
  S82409   IGHG1*03 (F) CH2 cDNA     --- --- --- --- --- --- 
                                
                                                             
  KT723008 IGHG1*04 F   CH2 gDNA     --- --- --- --- --- --- 
                                










                                                                                                                         
                                         
                                         1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                          G   P   A   R   E   P   Q   V   Y   V   L   A   P   P   Q   E 
  X16701   IGHG1*01 F   CH3-CHS gDNA                     ggg ccg gcc cgg gag ccg cag gtg tat gtc ctg gcc cca ccc cag gaa
                                    
                                                                                                                        
  X62916   IGHG1*02 (F) CH3-CHS cDNA                     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                    
                                                                                                                        
  S82409   IGHG1*03 (F) CH3-CHS cDNA                     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                    
                                                                                                                        
  KT723008 IGHG1*04 F   CH3-CHS gDNA                     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                    


                                                     _____AB_____                                            ____________
                                                     15.1    15.3                                                        
                                          13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                          E   L   S               K   S   T   V   S   L   T   C   M   V   T   S   F   Y 
  X16701   IGHG1*01 F   CH3-CHS gDNA     gag ctc agc ... ... ... aaa agc acg gtc agc ctc acc tgc atg gtc acc agc ttc tac
                                    
                                                                                                                        
  X62916   IGHG1*02 (F) CH3-CHS cDNA     --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                    
                                                                                                                        
  S82409   IGHG1*03 (F) CH3-CHS cDNA     --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                    
                                                                                                                        
  KT723008 IGHG1*04 F   CH3-CHS gDNA     --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                    


                                         _______BC___________________                            _____________CD_________
                                                                                                 45.1    45.3    45.5    
                                          30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                          P           D   Y   I   A   V   E   W   Q   R   N   G   Q   P   E   S   E   D 
  X16701   IGHG1*01 F   CH3-CHS gDNA     cca ... ... gac tac atc gcc gtg gag tgg cag aga aac ggg cag cct gag tcg gag gac
                                    
                                                                                                                        
  X62916   IGHG1*02 (F) CH3-CHS cDNA     --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                    
                                                                                                                        
  S82409   IGHG1*03 (F) CH3-CHS cDNA     --- ... ... --- --- --- --- --- --- --- --- --- --t --- --- --- --- --a --- ---
                                    
                                                                                                                        
  KT723008 IGHG1*04 F   CH3-CHS gDNA     --- ... ... --- --- --- --- --- --- --- --- --- --t --- --- --- --- --a --- ---
                                    


                                         ____                                ___________________________DE_______________
                                         45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                              77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                              K   Y   G   T   T   P   P   Q   L   D   A   D                           S 
  X16701   IGHG1*01 F   CH3-CHS gDNA     ... aag tac ggc acg acc ccg ccc cag ctg gac gcc gac ... ... ... ... ... ... agc
                                    
                                                                                                                        
  X62916   IGHG1*02 (F) CH3-CHS cDNA     ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---
                                    
                                                                                                                      G 
  S82409   IGHG1*03 (F) CH3-CHS cDNA     ... --- --- --- --- --- --t --- --- --- --- --- --- ... ... ... ... ... ... g--
                                    
                                                                                                                      G 
  KT723008 IGHG1*04 F   CH3-CHS gDNA     ... --- --- --- --- --- --t --- --- --- --- --- --- ... ... ... ... ... ... g--
                                    


                                         ____________                                                ___EF___            
                                             85.2                                                    96.1                
                                         85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                          S   Y   F   L   Y   S   K   L   R   V   D   R   N   S   W           Q   E   G 
  X16701   IGHG1*01 F   CH3-CHS gDNA     tcc tac ttc ctg tac agc aag ctc agg gtg gac agg aac agc tgg ... ... cag gaa gga
                                    
                                                                                                                        
  X62916   IGHG1*02 (F) CH3-CHS cDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---
                                    
                                                                  R                                                     
  S82409   IGHG1*03 (F) CH3-CHS cDNA     --- --- --- --- --- --- -g- --- --- --- --- --- --- --- --- ... ... --- --- ---
                                    
                                                                  R                                                     
  KT723008 IGHG1*04 F   CH3-CHS gDNA     --- --- --- --- --- --- -g- --- --- --- --- --- --- --- --- ... ... --- --- ---
                                    


                                                             _________________________FG_________________________        
                                         
                                         100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                          D   T   Y   T   C   V   V   M   H   E   A       L   H   N   H   Y   T   Q   K 
  X16701   IGHG1*01 F   CH3-CHS gDNA     gac acc tac acg tgt gtg gtg atg cac gag gcc ... ctg cac aat cac tac acg cag aag
                                    
                                                                                                                        
  X62916   IGHG1*02 (F) CH3-CHS cDNA     --- --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- ---
                                    
                                                                                                                        
  S82409   IGHG1*03 (F) CH3-CHS cDNA     --- --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- ---
                                    
                                                                                                                        
  KT723008 IGHG1*04 F   CH3-CHS gDNA     --- --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- ---
                                    


                                                                             __CHS___
                                         
                                         120 121 122 123 124 125 126 127 128 129 130 
                                          S   T   S   K   S   A               G   K  
  X16701   IGHG1*01 F   CH3-CHS gDNA     tcc acc tct aag tct gcg ... ... ... ggt aaa 
                                    
                                                                                     
  X62916   IGHG1*02 (F) CH3-CHS cDNA     --- --- --- --- --- --- ... ... ... --- --- 
                                    
                                                                                     
  S82409   IGHG1*03 (F) CH3-CHS cDNA     --- --- --- --- --- --- ... ... ... --- --- 
                                    
                                                                                     
  KT723008 IGHG1*04 F   CH3-CHS gDNA     --- --- --- --- --- --- ... ... ... --- --- 
                                    










                                     
                                     
                                      1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                      D   L   L   L   E   E   E   I   C   A   D   A   Q   D   G   E   L   D   G   L 
  KT723008 IGHG1*04 F M1+M2 gDNA     gac ctg ctg ctg gag gag gag atc tgt gcg gac gcc cag gac ggg gag ctg gac ggg ctc
                                


                                     
                                     
                                      21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40 
                                      W   T   T   I   S   I   F   I   T   L   F   L   L   S   V   C   Y   S   A   T 
  KT723008 IGHG1*04 F M1+M2 gDNA     tgg acg act atc tcc atc ttc atc aca ctc ttc ctg ctc agc gtc tgc tac agc gcc acc
                                


                                     
                                     
                                      41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60 
                                      V   T   L   F   K   V   K   W   I   F   S   S   V   V   E   L   K   R   T   I 
  KT723008 IGHG1*04 F M1+M2 gDNA     gtg acc ctc ttc aag gtg aag tgg atc ttc tca tca gtg gtg gag ctg aag agg acg atc
                                


                                     
                                     
                                      61  62  63  64  65  66  67  68  69  70  71  72 
                                      V   P   D   Y   R   N   M   I   G   Q   G   A  
  KT723008 IGHG1*04 F M1+M2 gDNA     gtc ccc gac tac aga aat atg atc ggg cag gga gcc 

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
07/11/2017
Authors:
Perrine Pégorier