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When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

                                                                                                                           
                                   
                                   1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                    X   S   T   T   A   P   K   V   Y   P   L   A   S   S   C   G 
  U63638   IGHG3*01 F CH1 gDNA                     ncc tcc acc aca gcc ccg aaa gtc tac cct ctg gca tcc agc tgc gga
                              
                                                                                                        R         
  U63639   IGHG3*02 F CH1 gDNA                     --- --- --- --- --- --- --- --- --- --- --- --- --- c-- --- ---
                              
                                                                                                                  
  KT723008 IGHG3*03 F CH1 gDNA                     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                              


                                               _____AB_____                                            ____________
                                               15.1    15.3                                                        
                                    13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                    D   T   S               S   S   T   V   T   L   G   C   L   V   S   S   Y   M 
  U63638   IGHG3*01 F CH1 gDNA     gac aca tcc ... ... ... agc tcc acc gtg acc ctg ggc tgc ctg gtc tcc agc tac atg
                              
                                                                                                                  
  U63639   IGHG3*02 F CH1 gDNA     --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                              
                                                                                                                  
  KT723008 IGHG3*03 F CH1 gDNA     --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                              


                                   _______BC___________________                            _____________CD_________
                                                                                           45.1    45.3    45.5    
                                    30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                    P           E   P   V   T   V   T   W   N   S   G   A   L   K   S             
  U63638   IGHG3*01 F CH1 gDNA     ccc ... ... gag ccg gtg acc gtg acc tgg aac tcg ggt gcc ctg aag agc ... ... ...
                              
                                                                                                                  
  U63639   IGHG3*02 F CH1 gDNA     --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --t ... ... ...
                              
                                                                                                                  
  KT723008 IGHG3*03 F CH1 gDNA     --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ...
                              


                                   ____                                ___________________________DE_______________
                                   45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                        77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                        G   V   H   T   F   P   A   V   R   Q   S   S                           G 
  U63638   IGHG3*01 F CH1 gDNA     ... ggc gtg cac acc ttc ccg gcc gtc cgg cag tcc tct ... ... ... ... ... ... ggg
                              
                                                                        L                                         
  U63639   IGHG3*02 F CH1 gDNA     ... --- --- --- --- --- --- --- --- -tt --- --- --c ... ... ... ... ... ... ---
                              
                                                                                                                  
  KT723008 IGHG3*03 F CH1 gDNA     ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---
                              


                                   ____________                                                ___EF___            
                                       85.2                                                    96.1                
                                   85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                    L   Y   S   L   S   S   M   V   T   V   P   A   S   S   S               E   T 
  U63638   IGHG3*01 F CH1 gDNA     ctg tac tct ctc agc agc atg gtg act gtg ccc gcc agc agc tca ... ... ... gaa acc
                              
                                                                                        T                         
  U63639   IGHG3*02 F CH1 gDNA     --- --- --- --- --- --- --- --- --c --- --- --- --- -c- --- ... ... ... --- ---
                              
                                                                                        T                   G     
  KT723008 IGHG3*03 F CH1 gDNA     --- --- --- --- --- --- --- --- --c --- --- --- --- -c- --- ... ... ... -g- ---
                              


                                                       _________________________FG_________________________        
                                   
                                   100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                    Q   T   F   T   C   N   V   A   H   P   A           S   S   T   K   V   D   K 
  U63638   IGHG3*01 F CH1 gDNA     cag acc ttc acc tgc aac gta gcc cac ccg gcc ... ... agc agc acc aag gtg gac aag
                              
                                                                                                                  
  U63639   IGHG3*02 F CH1 gDNA     --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- --- ---
                              
                                                                                                                  
  KT723008 IGHG3*03 F CH1 gDNA     --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- --- ---
                              


                                           
                                   
                                   120 121 
                                    A   V  
  U63638   IGHG3*01 F CH1 gDNA     gct gtc 
                              
                                           
  U63639   IGHG3*02 F CH1 gDNA     --- --- 
                              
                                           
  KT723008 IGHG3*03 F CH1 gDNA     --- --- 
                              










                                     
                                     
                                      1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                      T   A   R   R   P   V   P   T   T   P   K   T   T   I   P   P   G   K   P   T 
  U63638   IGHG3*01 F H1+H2 gDNA     act gca agg cgt cca gtc ccg acg acg cca aag aca act atc cct cct gga aaa ccc aca
                                
                                                                                                                    
  U63639   IGHG3*02 F H1+H2 gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --c --- --- --- --- --- --- ---
                                
                                                                                                                    
  KT723008 IGHG3*03 F H1+H2 gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --c --- --- --- --- --- --- ---
                                


                                     
                                     
                                      21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37 
                                      T   P   K   S   E   V   E   K   T   P   C   Q   C   S   K   C   P  
  U63638   IGHG3*01 F H1+H2 gDNA     acc cca aag tct gaa gtt gaa aag aca ccc tgc cag tgt tcc aaa tgc cca 
                                
                                          Q   E                                                          
  U63639   IGHG3*02 F H1+H2 gDNA     --- -ag g-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- 
                                
                                          Q   E   P                                                      
  KT723008 IGHG3*03 F H1+H2 gDNA     --- -ag g-- c-- --- --- --- --- --- --- --- --- --- --- --- --- --- 
                                










                                                                                                                   
                                   
                                   1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                    E   P   L   G   G   L   S   V   F   I   F   P   P   K   P   K 
  U63638   IGHG3*01 F CH2 gDNA                     gaa cct ctg gga gga ctg tct gtc ttc atc ttc cca ccg aaa ccc aag
                              
                                                                                                                  
  U63639   IGHG3*02 F CH2 gDNA                     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                              
                                                            P                                                     
  KT723008 IGHG3*03 F CH2 gDNA                     --- --- -c- --- --- --- --- --- --- --- --- --- --- --- --- ---
                              


                                               _____AB_____                                            ____________
                                               15.1    15.3                                                        
                                    13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                    D   T   L   T   I       S   G   T   P   E   V   T   C   V   V   V   D   V   G 
  U63638   IGHG3*01 F CH2 gDNA     gac acc ctc aca atc ... tcg gga acg ccc gag gtc acg tgt gtg gtg gtg gac gtg ggc
                              
                                                                                                                  
  U63639   IGHG3*02 F CH2 gDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                              
                                                                                                                  
  KT723008 IGHG3*03 F CH2 gDNA     --- --- --- --- --- ... --a --- --- --- --- --- --- --- --- --- --- --- --- ---
                              


                                   _______BC___________________                            _____________CD_________
                                                                                           45.1    45.3    45.5    
                                    30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                    Q   D   D   P   E   V   Q   F   S   W   F   V   D   D   V   E   V   H         
  U63638   IGHG3*01 F CH2 gDNA     cag gat gac ccc gag gtg cag ttc tcc tgg ttc gtg gac gac gtg gag gtg cac ... ...
                              
                                                                                                                  
  U63639   IGHG3*02 F CH2 gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ...
                              
                                                                                                                  
  KT723008 IGHG3*03 F CH2 gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ...
                              


                                   ____                                ___________________________DE_______________
                                   45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                        77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                        T   A   R   T   K   P   R   E   E   Q   F   N                           S 
  U63638   IGHG3*01 F CH2 gDNA     ... acg gcc agg acg aag ccg aga gag gag cag ttc aac ... ... ... ... ... ... agc
                              
                                                                                                                  
  U63639   IGHG3*02 F CH2 gDNA     ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---
                              
                                                                                                                  
  KT723008 IGHG3*03 F CH2 gDNA     ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---
                              


                                   ____________                                                ___EF___            
                                       85.2                                                    96.1                
                                   85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                    T   Y   R   V   V   S   A   L   R   I   Q   H   Q   D   W           L   Q   G 
  U63638   IGHG3*01 F CH2 gDNA     acc tac cgc gtg gtc agc gcc ctg cgc atc cag cac cag gac tgg ... ... ctg cag gga
                              
                                                                                                                  
  U63639   IGHG3*02 F CH2 gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---
                              
                                                                                                                  
  KT723008 IGHG3*03 F CH2 gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---
                              


                                                       _________________________FG_________________________        
                                   
                                   100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                    K   E   F   K   C   K   V   N   N   K   G           L   P   A   P   I   V   R 
  U63638   IGHG3*01 F CH2 gDNA     aag gag ttc aag tgc aag gtc aac aac aaa ggc ... ... ctc ccg gcc ccc att gtg agg
                              
                                                                                                                  
  U63639   IGHG3*02 F CH2 gDNA     --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- --- ---
                              
                                                                                                                  
  KT723008 IGHG3*03 F CH2 gDNA     --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- --- ---
                              


                                                           
                                   
                                   120 121 122 123 124 125 
                                    T   I   S   R   T   K  
  U63638   IGHG3*01 F CH2 gDNA     acc atc tcc agg acc aaa 
                              
                                                           
  U63639   IGHG3*02 F CH2 gDNA     --- --- --- --- --- --- 
                              
                                                           
  KT723008 IGHG3*03 F CH2 gDNA     --- --- --- --- --- --- 
                              










                                                                                                                       
                                       
                                       1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                        G   Q   A   R   E   P   Q   V   Y   V   L   A   P   P   R   E 
  U63638   IGHG3*01 F CH3-CHS gDNA                     ggg cag gcc cgg gag ccg cag gtg tat gtc ctg gcc cca ccc cgg gaa
                                  
                                                                                                                      
  U63639   IGHG3*02 F CH3-CHS gDNA                     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                  
                                                                                L                                     
  KT723008 IGHG3*03 F CH3-CHS gDNA                     --- --- --- --- --- --- -t- --- --- --- --- --- --- --- --- ---
                                  


                                                   _____AB_____                                            ____________
                                                   15.1    15.3                                                        
                                        13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                        E   L   S               K   S   T   L   S   L   T   C   L   I   T   G   F   Y 
  U63638   IGHG3*01 F CH3-CHS gDNA     gag ctc agc ... ... ... aaa agc acg ctc agc ctc acc tgc ctg atc acc ggt ttc tac
                                  
                                                                                                                      
  U63639   IGHG3*02 F CH3-CHS gDNA     --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                  
                                                                                                                      
  KT723008 IGHG3*03 F CH3-CHS gDNA     --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                  


                                       _______BC___________________                            _____________CD_________
                                                                                               45.1    45.3    45.5    
                                        30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                        P           E   E   I   D   V   E   W   Q   R   N   G   Q   P   E   S   E   D 
  U63638   IGHG3*01 F CH3-CHS gDNA     cca ... ... gaa gag ata gac gtg gag tgg cag aga aat ggg cag cct gag tcg gag gac
                                  
                                                                                                                      
  U63639   IGHG3*02 F CH3-CHS gDNA     --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                  
                                                                                                                      
  KT723008 IGHG3*03 F CH3-CHS gDNA     --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --a --- ---
                                  


                                       ____                                ___________________________DE_______________
                                       45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                            77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                            K   Y   H   T   T   A   P   Q   L   D   A   D                           G 
  U63638   IGHG3*01 F CH3-CHS gDNA     ... aag tac cac acg acc gca ccc cag ctg gat gct gac ... ... ... ... ... ... ggc
                                  
                                                                                                                      
  U63639   IGHG3*02 F CH3-CHS gDNA     ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---
                                  
                                                                                                                      
  KT723008 IGHG3*03 F CH3-CHS gDNA     ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---
                                  


                                       ____________                                                ___EF___            
                                           85.2                                                    96.1                
                                       85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                        S   Y   F   L   Y   S   K   L   R   V   N   K   S   S   W           Q   E   G 
  U63638   IGHG3*01 F CH3-CHS gDNA     tcc tac ttc ctg tac agc aag ctc agg gtg aac aag agc agc tgg ... ... cag gaa gga
                                  
                                                                R                                                     
  U63639   IGHG3*02 F CH3-CHS gDNA     --- --- --- --- --- --- -g- --- --- --- --- --- --- --- --- ... ... --- --- ---
                                  
                                                                R                                                     
  KT723008 IGHG3*03 F CH3-CHS gDNA     --- --- --- --- --- --- -g- --- --- --- --- --- --- --- --- ... ... --- --- ---
                                  


                                                           _________________________FG_________________________        
                                       
                                       100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                        D   H   Y   T   C   A   V   M   H   E   A       L   R   N   H   Y   K   E   K 
  U63638   IGHG3*01 F CH3-CHS gDNA     gac cac tac acg tgt gca gtg atg cac gaa gct ... tta cgg aat cac tac aaa gag aag
                                  
                                                                                                                      
  U63639   IGHG3*02 F CH3-CHS gDNA     --- --- --- --- --- --- --- --- --t --- --- ... --- --- --- --- --- --- --- ---
                                  
                                                                                                                      
  KT723008 IGHG3*03 F CH3-CHS gDNA     --- --- --- --- --- --- --- --- --t --- --- ... --- --- --- --- --- --- --- ---
                                  


                                                                           __CHS___
                                       
                                       120 121 122 123 124 125 126 127 128 129 130 
                                        S   I   S   R   S   P               G   K  
  U63638   IGHG3*01 F CH3-CHS gDNA     tcc atc tcg agg tct ccg ... ... ... ggt aaa 
                                  
                                                                                   
  U63639   IGHG3*02 F CH3-CHS gDNA     --- --- --- --- --- --- ... ... ... --- --- 
                                  
                                                                                   
  KT723008 IGHG3*03 F CH3-CHS gDNA     --- --- --- --- --- --- ... ... ... --- --- 
                                  










                                     
                                     
                                      1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                      D   L   L   L   E   E   E   I   C   A   D   D   L   D   G   E   L   D   G   L 
  KT723008 IGHG3*03 F M1+M2 gDNA     gac ttg ctg ctg gag gag gag atc tgt gcg gac gac ctg gat ggg gag ctg gac ggg ctc
                                


                                     
                                     
                                      21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40 
                                      W   T   T   I   S   I   F   I   T   L   F   L   L   S   V   C   Y   S   A   T 
  KT723008 IGHG3*03 F M1+M2 gDNA     tgg acg act atc tcc atc ttc atc aca ctc ttc ctg ctc agc gtc tgc tac agc gcc act
                                


                                     
                                     
                                      41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60 
                                      V   T   L   F   K   V   K   W   I   F   S   S   A   V   E   L   K   R   T   I 
  KT723008 IGHG3*03 F M1+M2 gDNA     gtg acc ctc ttc aag gtg aaa tgg atc ttc tcc tcg gcg gtg gag ctg aag agg acg atc
                                


                                     
                                     
                                      61  62  63  64  65  66  67  68  69  70  71  72 
                                      V   P   D   Y   R   N   M   L   G   Q   G   A  
  KT723008 IGHG3*03 F M1+M2 gDNA     gtc ccc gac tac aga aac atg ctc ggg cag ggc gcc 

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux, Mehdi Yousfi and Perrine Pégorier).

Created:
07/11/2017
Authors:
Perrine Pégorier