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When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

                                                                                                                 5'->3'
                                                                                                           (direct orientation)
                                          1        10        20        30        40        50        60        70        80        90       100       110       120       130       140
                                          |........|.........|.........|.........|.........|.........|.........|.........|.........|.........|.........|.........|.........|.........|........

                                           V  V  V  L  M  V  I  V  M  V  M  V  V  V  M  V  M  V  V  V  V  M  I  V  M  V  M  V  V  M  V  V  M  V  V  M  V  I  V  V  I  V  I  V  I  L  T  N  I
                                            *  L  S  *  W  L  *  L  W  L  W  L  W  L  W  L  W  L  *  W  L  *  L  L  W  L  W  W  L  W  W  L  W  W  L  W  L  *  *  L  *  L  *  L  Y  L  R  I  Y
                                             S  C  P  D  G  Y  S  Y  G  Y  G  C  G  Y  G  Y  G  C  S  G  Y  D  C  Y  G  Y  G  G  Y  G  G  Y  G  G  Y  G  Y  S  S  Y  S  Y  S  Y  T  Y  E  Y
  KT723008 IGHD8-2*01 F D-REGION gDNA     gtagttgtcctgatggttatagttatggttatggttgtggttatggttatggttgtagtggttatgattgttatggttatggtggttatggtggttatggtggttatggttatagtagttatagttatagttatacttacgaatatac
     
                                     
                                                                                                                                                                                                                                                                                                                                                                  
                                                                                                                                                                                                                                                                                                                                                                  
                                                                                                                                                                                                                                                                                                                                                                  
  AY559839 IGHD8-2*01 F D-REGION gDNA     ----------------------------------------------------------------------------------------------------------------------------------------------------







                                                                                                                 3'<-5'
                                                                                                           (inverted orientation)
                                          1        10        20        30        40        50        60        70        80        90       100       110       120       130       140
                                          |........|.........|.........|.........|.........|.........|.........|.........|.........|.........|.........|.........|.........|.........|........

                                           V  Y  S  *  V  *  L  *  L  *  L  L  *  P  *  P  P  *  P  P  *  P  P  *  P  *  Q  S  *  P  L  Q  P  *  P  *  P  Q  P  *  P  *  L  *  P  S  G  Q  L
                                            Y  I  R  K  Y  N  Y  N  Y  N  Y  Y  N  H  N  H  H  N  H  H  N  H  H  N  H  N  N  H  N  H  Y  N  H  N  H  N  H  N  H  N  H  N  Y  N  H  Q  D  N  Y
                                             I  F  V  S  I  T  I  T  I  T  T  I  T  I  T  T  I  T  T  I  T  T  I  T  I  T  I  I  T  T  T  T  I  T  I  T  T  T  I  T  I  T  I  T  I  R  T  T
  KT723008 IGHD8-2*01 F D-REGION gDNA     gtatattcgtaagtataactataactataactactataaccataaccaccataaccaccataaccaccataaccataacaatcataaccactacaaccataaccataaccacaaccataaccataactataaccatcaggacaactac
     
                                     
                                                                                                                                                                                                                                                                                                                                                                  
                                                                                                                                                                                                                                                                                                                                                                  
                                                                                                                                                                                                                                                                                                                                                                  
  AY559839 IGHD8-2*01 F D-REGION gDNA     ----------------------------------------------------------------------------------------------------------------------------------------------------
                                              



Legend:
*: STOP-CODON

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
07/11/2017
Last updated:
11/12/2017
Authors:
Perrine Pégorier