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When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

                                                                                                                                   
                                           
                                            1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                            Q   V   Q   L   R   E   S   G   P       S   L   V   K   P   S   Q   T   L   S 
  KT723008 IGHV1-20*01 F V-REGION gDNA     cag gtg cag ctg cgg gag tcg ggc ccc ... agc ctg gtg aag ccc tca cag acc ctc tcc
                                      
                                                                                                                          
  U55169   IGHV1-20*02 F V-REGION gDNA     --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---
                                      


                                                                   ___________________CDR1-IMGT____________________        
                                           
                                            21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40 
                                            L   T   C   T   V   S   G   F   S   L                   S   S   Y   A   V   G 
  KT723008 IGHV1-20*01 F V-REGION gDNA     ctc acc tgc acg gtc tct gga ttc tca ctg ... ... ... ... agc agc tat gct gta ggc
                                      
                                                                                                        D   N   S         
  U55169   IGHV1-20*02 F V-REGION gDNA     --- --- --- --- --- --- --- --- --- t-a ... ... ... ... --- gat a-- ag- --- ---
                                      


                                                                                                       _______________CDR2-
                                           
                                            41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60 
                                            W   V   R   Q   A   P   G   K   A   L   E   W   L   G   G   I   S   S   G     
  KT723008 IGHV1-20*01 F V-REGION gDNA     tgg gtc cgc cag gct cca ggg aag gcg ctg gag tgg ctc ggt ggt ata agc agt ggt ...
                                      
                                                                                        C                                 
  U55169   IGHV1-20*02 F V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --c --- --- --- --- --- --- --- ...
                                      


                                           IMGT________________                                                            
                                           
                                            61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79  80 
                                                    G   S   T   Y   Y   N   P   A   L   K       S   R   L   S   I   T   K 
  KT723008 IGHV1-20*01 F V-REGION gDNA     ... ... gga agc aca tac tat aac cca gcc ctg aaa ... tcc cgg ctc agc atc acc aag
                                      
                                                                G                                                         
  U55169   IGHV1-20*02 F V-REGION gDNA     ... ... --- --- --- gg- --- --- --- --- --- --- ... --- --- --- --- --- --- ---
                                      


                                                                                                                           
                                           
                                            81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 100 
                                            D   N   S   K   S   Q   V   S   L   S   V   S   S   V   T   P   E   D   T   A 
  KT723008 IGHV1-20*01 F V-REGION gDNA     gac aac tcc aag agc caa gtc tct ctg tca gtg agc agc gtg aca cct gag gac acg gcc
                                      
                                                                                                                          
  U55169   IGHV1-20*02 F V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --a ---
                                      


                                                           _CDR3-IMGT__
                                           
                                           101 102 103 104 105 106 
                                            T   Y   Y   C   A   K  
  KT723008 IGHV1-20*01 F V-REGION gDNA     aca tac tac tgt gcg aag ga
                                      
                                                           
  U55169   IGHV1-20*02 F V-REGION gDNA     --- --- --- --- 

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
07/11/2017
Authors:
Perrine Pégorier