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When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

	
	
	                                                                                
                                      
                                      1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                       X   S   K   T   S   P   S   V   F   P   L   S   L   C   H   Q 
  AAEX03006125 IGHA*01 F CH1 gDNA                     nag tcc aaa acc agc ccc agt gtg ttc ccg ctg agc ctc tgc cac cag
                                                                                                                     
  L36871       IGHA*02 F CH1 gDNA                     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                  _____AB_____                                            ____________
                                                  15.1    15.3                                                        
                                       13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                       E   S                   E   G   Y   V   V   I   G   C   L   V   Q   G   F   F 
  AAEX03006125 IGHA*01 F CH1 gDNA     gag tca ... ... ... ... gaa ggg tac gtg gtc atc ggc tgc ctg gtg cag gga ttc ttc
                                                                                                                     
  L36871       IGHA*02 F CH1 gDNA     --- --- ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                      _______BC___________________                            _____________CD_________
                                                                                              45.1    45.3    45.5    
                                       30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                       P   P       E   P   V   N   V   T   W   N   A   G   K   D   S   T             
  AAEX03006125 IGHA*01 F CH1 gDNA     cca ccg ... gag cct gtg aac gtg acc tgg aat gcc ggc aag gac agc aca ... ... ...
                                                                                                                     
  L36871       IGHA*02 F CH1 gDNA     --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ...


                                      ____                                ___________________________DE_______________
                                      45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                           77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                           S   V   K   N   F   P   P   M   K   A   A   T   G                       S 
  AAEX03006125 IGHA*01 F CH1 gDNA     ... tct gtc aag aac ttc ccc ccc atg aag gct gct acc gga ... ... ... ... ... agc
                                                                                                                     
  L36871       IGHA*02 F CH1 gDNA     ... --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ---


                                      ____________                                                ___EF___            
                                          85.2                                                    96.1                
                                      85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                       L   Y   T   M   S   S   Q   L   T   L   P   A   A   Q   C           P   D   D 
  AAEX03006125 IGHA*01 F CH1 gDNA     cta tac acc atg agc agc cag ttg acc ctg cca gcc gcc cag tgc ... ... cct gat gac
                                                                                                                     
  L36871       IGHA*02 F CH1 gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---


                                                          _________________________FG_________________________        
                                      
                                      100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                       S   S   V   K   C   Q   V   Q   H   A               S   S   P   S   K   A   V 
  AAEX03006125 IGHA*01 F CH1 gDNA     tcg tct gtg aaa tgc caa gtg cag cat gct ... ... ... tcc agc ccc agc aag gca gtg
                                                                                                                     
  L36871       IGHA*02 F CH1 gDNA     --- --- --- --- --- --- --- --- --- --- ... ... ... --- --- --- --- --- --- ---


                                                          
                                      
                                      120 121 122 123 124 
                                       S   V   P   C   K  
  AAEX03006125 IGHA*01 F CH1 gDNA     tct gtg ccc tgc aaa 
                                                          
  L36871       IGHA*02 F CH1 gDNA     --- --- --- --- --- 



                                       1   2   3   4   5   6   7   8   9   10  11  12 
                                       D   N   C   H   P   C   P   H   P   S   P   S  
  AAEX03006125 IGHA*01 F H gDNA       gat aac tgt cat ccg tgt cct cat cca agt ccc tcg 
                                               S               H   P  
  L36871       IGHA*02 F H gDNA       --- --- a-- --- --- --- -a- -ca 



                                      1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                               C   N   E   P   R   L   S   L   Q   K   P   A   L   E 
  AAEX03006125 IGHA*01 F CH2 gDNA                             tgc aat gag ccc cgc ctg tca cta cag aag cca gcc ctc gag
                                                                                                         
  L36871       IGHA*02 F CH2 gDNA                             --- --- --- --- --- --- --- --- --- --- --- --- --- ---

                                                    
                                                    _____AB_____                                            ____________
                                                    15.1    15.3                                                        
                                         13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                         D   L   L   L           G   S   N   A   S   L   T   C   T   L   S   G   L   K 
  AAEX03006125 IGHA*01 F CH2 gDNA       gat ctg ctt tta ... ... ggc tcc aat gcc agc ctc aca tgc aca ctg agt ggc ctg aaa
                                                                                                         
  L36871       IGHA*02 F CH2 gDNA       --- --- --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                          
                          
                                        _______BC___________________                            _____________CD_________
                                                                                                45.1    45.3    45.5    
                                         30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                         D   P       K   G   A   T   F   T   W   N   P   S   K   G   K   E             
  AAEX03006125 IGHA*01 F CH2 gDNA       gac ccc ... aag ggt gcc acc ttc acc tgg aac ccc tcc aaa ggg aag gaa ... ... ...
                                                                                                         
  L36871       IGHA*02 F CH2 gDNA       --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ...
                          
                          
                                        ____                                ___________________________DE_______________
                                        45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                             77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                             P   I   Q   K   N   P   E   R   D   S   C   G                             
  AAEX03006125 IGHA*01 F CH2 gDNA       ... ccc atc cag aag aat cct gag cgt gac tcc tgt ggc ... ... ... ... ... ... ...
                                                                                                         
  L36871       IGHA*02 F CH2 gDNA       ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ...
                          
                          
                                        ____________                                                ___EF___            
                                            85.2                                                    96.1                
                                        85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                         C   Y   S   V   S   S   V   L   P   G   C   A   D   P   W           N   H   G 
  AAEX03006125 IGHA*01 F CH2 gDNA       tgc tac agt gtg tcc agt gtc cta cca ggc tgt gct gat cca tgg ... ... aac cat ggg
                                                                                                         
  L36871       IGHA*02 F CH2 gDNA       --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---
                          
                          
                                                            _________________________FG_________________________        
                                        
                                        100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                         D   T   F   S   C   T   A   T   H   P   E           S   K   S   P   I   T   V 
  AAEX03006125 IGHA*01 F CH2 gDNA       gac acc ttc tcc tgc aca gcc acc cac cct gaa ... ... tcc aag agc ccg atc act gtc
                                                                                                         
  L36871       IGHA*02 F CH2 gDNA       --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- --- ---
                          
                          
                                                            
                                        
                                        120 121 122 123 124 
                                         S   I   T   K   T   T  
  AAEX03006125 IGHA*01 F CH2 gDNA       agc atc acc aaa acc aca 
                                                  
  L36871       IGHA*02 F CH2 gDNA       --- --- --- --- --- --- 
                                                                                                                          
                                          
                                          1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                               E   H   I   P   P   Q   V   H   L   L   P   P   P   S   E 
  AAEX03006125 IGHA*01 F CH3-CHS gDNA                         gag cac atc ccg ccc cag gtc cac ctg ctg ccg ccg ccg tcg gaa
                                                                                                                         
  L36871       IGHA*02 F CH3-CHS gDNA                         --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                      _____AB_____                                            ____________
                                                      15.1    15.3                                                        
                                           13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                           E   L   A   L           N   E   L   V   T   L   T   C   L   V   R   G   F   K 
  AAEX03006125 IGHA*01 F CH3-CHS gDNA     gag ctg gcc ctc ... ... aat gag ctg gtg aca ctg acg tgc ttg gtg agg ggc ttc aaa
                                                                                                                         
  L36871       IGHA*02 F CH3-CHS gDNA     --- --- --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                          _______BC___________________                            _____________CD_________
                                                                                                  45.1    45.3    45.5    
                                           30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                           P           K   D   V   L   V   R   W   L   Q   G   T   Q   E   L   P   Q   E 
  AAEX03006125 IGHA*01 F CH3-CHS gDNA     cca ... ... aaa gat gtg ctc gta cga tgg ctg caa ggg acc cag gag cta ccc caa gag
                                                                                                                         
  L36871       IGHA*02 F CH3-CHS gDNA     --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                          ____                                ___________________________DE_______________
                                          45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                               77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                               K   Y   L   T   W   E   P   L   K   E   P   D   Q                   T   N 
  AAEX03006125 IGHA*01 F CH3-CHS gDNA     ... aag tac ttg acc tgg gag ccc ctg aag gag cct gac cag ... ... ... ... acc aac
                                                                                                                         
  L36871       IGHA*02 F CH3-CHS gDNA     ... --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- ---


                                          ____________                                                ___EF___            
                                              85.2                                                    96.1                
                                          85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                           M   F   A   V   T   S   M   L   R   V   T   A   E   D   W           K   Q   G 
  AAEX03006125 IGHA*01 F CH3-CHS gDNA     atg ttt gcc gtg acc agc atg ctg agg gtg aca gcc gaa gac tgg ... ... aag cag ggg
                                                                                                                         
  L36871       IGHA*02 F CH3-CHS gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---


                                                              _________________________FG_________________________        
                                          
                                          100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                           E   K   F   S   C   M   V   G   H   E   A       L   P   M   S   F   T   Q   K 
  AAEX03006125 IGHA*01 F CH3-CHS gDNA     gag aag ttc tcc tgc atg gtg ggc cac gag gct ... ctg ccc atg tcc ttc acc cag aag
                                                                                                                         
  L36871       IGHA*02 F CH3-CHS gDNA     --- --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- ---


                                                                              ______________________________________CHS___
                                          
                                          120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 
                                           T   I   D   R   L   A               G   K   P   T   H   V   N   V   S   V   V 
  AAEX03006125 IGHA*01 F CH3-CHS gDNA     acc atc gac cgc ctg gcg ... ... ... ggt aaa ccc acc cac gtc aac gtg tct gtg gtc
                                                                                                                         
  L36871       IGHA*02 F CH3-CHS gDNA     --- --- --- --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- ---


                                          ____________________________________
                                          
                                          140 141 142 143 144 145 146 147 148 
                                           M   A   E   V   D   G   I   C   Y  
  AAEX03006125 IGHA*01 F CH3-CHS gDNA     atg gca gag gtg gac ggc atc tgc tac 
                                                                              
  L36871       IGHA*02 F CH3-CHS gDNA     --- --- --- --- --- --- --- --- --- 
                                    
                                    
                                     1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                     D   S   Q   C   L   A   G   Y   R   E   P   L   P   W   L   V   L   D   L   S 
  AAEX03006125 IGHA*01 F M gDNA     gac tca cag tgt ctt gca ggt tac cgg gag cca ctt ccc tgg ctg gtg ctg gac ctg tcg


                                    
                                    
                                     21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40 
                                     Q   E   D   L   E   E   D   A   P   G   A   S   L   W   P   T   T   V   T   L 
  AAEX03006125 IGHA*01 F M gDNA     cag gag gac ctg gag gag gat gcc cca gga gcc agc ctg tgg ccc act acc gtc acc ctt


                                    
                                    
                                     41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60 
                                     L   T   L   F   L   L   S   L   F   Y   S   T   A   L   T   V   T   S   V   R 
  AAEX03006125 IGHA*01 F M gDNA     ctc acc ctc ttc cta ctg agt ctc ttc tac agc aca gca ctg act gtg aca agc gtg cgg


                                    
                                    
                                     61  62  63  64  65  66  67  68  69  70  71 
                                     G   P   T   D   S   R   E   G   P   Q   Y  
  AAEX03006125 IGHA*01 F M gDNA     ggc cca act gac agc aga gag ggc ccc cag tac 

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
05/05/2015
Last updated:
21/05/2015
Authors:
Saida Hadi-Saljoqi