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When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

	
	
	                                                                                                                       
                                       
                                       1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                        X   S   T   T   A   P   S   V   F   P   L   A   P   S   C   G 
  AAEX03006126 IGHG2*01  F  CH1 gDNA                   ncc tcc acc acg gcc ccc tcg gtt ttc cca ctg gcc ccc agc tgc ggg
                                                        A                                                             
  AF354265     IGHG2*02 (F) CH1 cDNA                   g-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                   _____AB_____                                            ____________
                                                   15.1    15.3                                                        
                                        13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                        S   T   S               G   S   T   V   A   L   A   C   L   V   S   G   Y   F 
  AAEX03006126 IGHG2*01  F  CH1 gDNA   tcc act tcc ... ... ... ggc tcc acg gtg gcc ctg gcc tgc ctg gtg tca ggc tac ttc
                                                                                                                      
  AF354265     IGHG2*02 (F) CH1 cDNA   --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                       _______BC___________________                            _____________CD_________
                                                                                               45.1    45.3    45.5    
                                        30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                        P           E   P   V   T   V   S   W   N   S   G   S   L   T   S             
  AAEX03006126 IGHG2*01  F  CH1 gDNA   ccc ... ... gag cct gta act gtg tcc tgg aat tcc ggc tcc ttg acc agc ... ... ...
                                                                                                                      
  AF354265     IGHG2*02 (F) CH1 cDNA   --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ...


                                       ____                                ___________________________DE_______________
                                       45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                            77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                            G   V   H   T   F   P   S   V   L   Q   S   S                           G 
  AAEX03006126 IGHG2*01  F  CH1 gDNA   ... ggt gtg cac acc ttc ccg tcc gtc ctg cag tcc tca ... ... ... ... ... ... ggg
                                                                                                                      
  AF354265     IGHG2*02 (F) CH1 cDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---


                                       ____________                                                ___EF___            
                                           85.2                                                    96.1                
                                       85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                        L   Y   S   L   S   S   M   V   T   V   P   S   S   R   W               P   S 
  AAEX03006126 IGHG2*01  F  CH1 gDNA   ctc tac tcc ctc agc agc atg gtg aca gtg ccc tcc agc agg tgg ... ... ... ccc agc
                                                                                                                      
  AF354265     IGHG2*02 (F) CH1 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... --- ---


                                                           _________________________FG_________________________        
                                       
                                       100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                        E   T   F   T   C   N   V   A   H   P   A           S   K   T   K   V   D   K 
  AAEX03006126 IGHG2*01  F  CH1 gDNA   gag acc ttc acc tgc aac gtg gcc cac ccg gcc ... ... agc aaa act aaa gta gac aag
                                                                                                                      
  AF354265     IGHG2*02 (F) CH1 cDNA   --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- --- ---


                                           
                                       
                                       120 
                                        P  
  AAEX03006126 IGHG2*01  F  CH1 gDNA   cca 
                                           
  AF354265     IGHG2*02 (F) CH1 cDNA   --- 


                                                                         
                                      1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19 
                                      V   P   K   R   E   N   G   R   V   P   R   P   P   D   C   P   K   C   P  
  AAEX03006126 IGHG2*01  F  H gDNA   gtg ccc aaa aga gaa aat gga aga gtt cct cgc cca cct gat tgt ccc aaa tgc cca 
                                                                                                                 
  AF354265     IGHG2*02 (F) H cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- 



                                                                                                                       
                                       
                                       1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                A   P   E   M   L   G   G   P   S   V   F   I   F   P   P   K   P   K 
  AAEX03006126 IGHG2*01  F  CH2 gDNA           gcc cct gaa atg ctg gga ggg cct tcg gtc ttc atc ttt ccc ccg aaa ccc aag
                                                                                                                      
  AF354265     IGHG2*02 (F) CH2 cDNA           --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                   _____AB_____                                            ____________
                                                   15.1    15.3                                                        
                                        13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                        D   T   L   L   I       A   R   T   P   E   V   T   C   V   V   V   D   L   D 
  AAEX03006126 IGHG2*01  F  CH2 gDNA   gac acc ctc ttg att ... gcc cga aca cct gag gtc aca tgt gtg gtg gtg gat ctg gac
                                                                                                                      
  AF354265     IGHG2*02 (F) CH2 cDNA   --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                       _______BC___________________                            _____________CD_________
                                                                                               45.1    45.3    45.5    
                                        30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                        P   E   D   P   E   V   Q   I   S   W   F   V   D   G   K   Q   M   Q         
  AAEX03006126 IGHG2*01  F  CH2 gDNA   cca gaa gac cct gag gtg cag atc agc tgg ttc gtg gac ggt aag cag atg caa ... ...
                                                                                                                      
  AF354265     IGHG2*02 (F) CH2 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ...


                                       ____                                ___________________________DE_______________
                                       45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                            77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                            T   A   K   T   Q   P   R   E   E   Q   F   N                           G 
  AAEX03006126 IGHG2*01  F  CH2 gDNA   ... aca gcc aag act cag cct cgt gag gag cag ttc aat ... ... ... ... ... ... ggc
                                                                                                                      
  AF354265     IGHG2*02 (F) CH2 cDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---


                                       ____________                                                ___EF___            
                                           85.2                                                    96.1                
                                       85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                        T   Y   R   V   V   S   V   L   P   I   G   H   Q   D   W           L   K   G 
  AAEX03006126 IGHG2*01  F  CH2 gDNA   acc tac cgt gtg gtc agt gtc ctc ccc att ggg cac cag gac tgg ... ... ctc aag ggg
                                                                                                                      
  AF354265     IGHG2*02 (F) CH2 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---


                                                           _________________________FG_________________________        
                                       
                                       100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                        K   Q   F   T   C   K   V   N   N   K   A           L   P   S   P   I   E   R 
  AAEX03006126 IGHG2*01  F  CH2 gDNA   aag cag ttc acg tgc aaa gtc aac aac aaa gcc ... ... ctc cca tcc ccg atc gag agg
                                                                                                                      
  AF354265     IGHG2*02 (F) CH2 cDNA   --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- --- ---


                                                               
                                       
                                       120 121 122 123 124 125 
                                        T   I   S   K   A   R  
  AAEX03006126 IGHG2*01  F  CH2 gDNA   acc atc tcc aag gcc aga 
                                                               
  AF354265     IGHG2*02 (F) CH2 cDNA   --- --- --- --- --- --- 



                                                                                                                           
                                           
                                           1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                            G   Q   A   H   Q   P   S   V   Y   V   L   P   P   S   R   E 
  AAEX03006126 IGHG2*01  F  CH3-CHS gDNA                   ggg cag gcc cat caa ccc agt gtg tat gtc ctg ccg cca tcc cgg gag
                                                                                                                          
  AF354265     IGHG2*02 (F) CH3-CHS cDNA                   --- --a --- --- --g --- --- --- --- --- --- --- --- --- --- ---


                                                       _____AB_____                                            ____________
                                                       15.1    15.3                                                        
                                            13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                            E   L   S               K   N   T   V   S   L   T   C   L   I   K   D   F   F 
  AAEX03006126 IGHG2*01  F  CH3-CHS gDNA   gag ttg agc ... ... ... aag aac aca gtc agc ttg aca tgc ctg atc aaa gac ttc ttc
                                                                                                                          
  AF354265     IGHG2*02 (F) CH3-CHS cDNA   --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                           _______BC___________________                            _____________CD_________
                                                                                                   45.1    45.3    45.5    
                                            30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                            P           P   D   I   D   V   E   W   Q   S   N   G   Q   Q   E   P   E   S 
  AAEX03006126 IGHG2*01  F  CH3-CHS gDNA   cca ... ... cct gac att gat gtg gag tgg cag agc aat gga cag cag gag cct gag agc
                                                                                                                          
  AF354265     IGHG2*02 (F) CH3-CHS cDNA   --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                           ____                                ___________________________DE_______________
                                           45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                                77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                                K   Y   R   T   T   P   P   Q   L   D   E   D                           G 
  AAEX03006126 IGHG2*01  F  CH3-CHS gDNA   ... aag tac cgc acg acc ccg ccc cag ctg gac gag gac ... ... ... ... ... ... ggg
                                                                                                                          
  AF354265     IGHG2*02 (F) CH3-CHS cDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---


                                           ____________                                                ___EF___            
                                               85.2                                                    96.1                
                                           85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                            S   Y   F   L   Y   S   K   L   S   V   D   K   S   R   W           Q   R   G 
  AAEX03006126 IGHG2*01  F  CH3-CHS gDNA   tcc tac ttc ctg tac agc aag ctc tct gtg gac aag agc cgc tgg ... ... cag cgg gga
                                                                                                                          
  AF354265     IGHG2*02 (F) CH3-CHS cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---


                                                               _________________________FG_________________________        
                                           
                                           100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                            D   T   F   I   C   A   V   M   H   E   A       L   H   N   H   Y   T   Q   K 
  AAEX03006126 IGHG2*01  F  CH3-CHS gDNA   gac acc ttc ata tgt gcg gtg atg cat gaa gct ... cta cac aac cac tac aca cag aaa
                                                                                                                        E 
  AF354265     IGHG2*02 (F) CH3-CHS cDNA   --- --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- g--


                                                                               __CHS___
                                           
                                           120 121 122 123 124 125 126 127 128 129 130 
                                            S   L   S   H   S   P               G   K  
  AAEX03006126 IGHG2*01  F  CH3-CHS gDNA   tcc ctc tcc cat tct ccg ... ... ... ggt aaa 
                                                                                       
  AF354265     IGHG2*02 (F) CH3-CHS cDNA   --- --- --- --- --- --- ... ... ... --- --- 

                                         
                                         
                                          1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                          E   L   I   L   D   D   S   C   A   E   D   Q   D   G   E   L   D   G   L   W 
  AAEX03006126 IGHG2*01 F M1+M2 gDNA     gag ctg atc ctg gat gac agc tgt gct gag gac cag gac ggg gag ctg gac ggg ctg tgg


                                         
                                         
                                          21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40 
                                          T   T   I   S   I   F   I   T   L   F   L   L   S   V   C   Y   S   A   T   V 
  AAEX03006126 IGHG2*01 F M1+M2 gDNA     acc acc atc tcc atc ttc atc acc ctc ttc ctg ctc agc gtg tgc tac agc gcc act gtc


                                         
                                         
                                          41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60 
                                          T   L   F   K   V   K   W   I   F   S   S   V   V   E   L   K   R   T   I   V 
  AAEX03006126 IGHG2*01 F M1+M2 gDNA     acc ctc ttc aag gtg aag tgg atc ttc tca tca gtg gtg gag ctg aag cgc acg att gtc


                                         
                                         
                                          61  62  63  64  65  66  67  68  69  70  71 
                                          P   D   Y   R   N   M   I   G   Q   G   A  
  AAEX03006126 IGHG2*01 F M1+M2 gDNA     ccc gac tac agg aat atg atc ggg cag ggg gcc 

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
05/05/2015
Last updated:
20/05/2015
Authors:
Saida Hadi-Saljoqi