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When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

	
	
	
                                                      
                                                                                                                                       
                                   
                                   1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                    A   S   T   T   A   P   S   V   F   P   L   A   P   S   C   G 
  AF354267 IGHG4*01 (F) CH1 cDNA                   gcc tcc acc acg gcc ccc tcg gtt ttc cca ctg gcc ccc agc tgc ggg


                                               _____AB_____                                            ____________
                                               15.1    15.3                                                        
                                    13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                    S   T   S               G   S   T   V   A   L   A   C   L   V   S   G   Y   F 
  AF354267 IGHG4*01 (F) CH1 cDNA   tcc act tcc ... ... ... ggc tcc acg gtg gcc ctg gcc tgc ctg gtg tca ggc tac ttc


                                   _______BC___________________                            _____________CD_________
                                                                                           45.1    45.3    45.5    
                                    30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                    P           E   P   V   T   V   S   W   N   S   G   S   L   T   S             
  AF354267 IGHG4*01 (F) CH1 cDNA   ccc ... ... gag cct gta act gtg tcc tgg aat tcc ggc tcc ttg acc agc ... ... ...


                                   ____                                ___________________________DE_______________
                                   45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                        77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                        G   V   H   T   F   P   S   V   L   Q   S   S                           G 
  AF354267 IGHG4*01 (F) CH1 cDNA   ... ggt gtg cac acc ttc ccg tcc gtc ctg cag tcc tca ... ... ... ... ... ... ggg


                                   ____________                                                ___EF___            
                                       85.2                                                    96.1                
                                   85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                    L   Y   S   L   S   S   T   V   T   V   P   S   S   R   W               P   S 
  AF354267 IGHG4*01 (F) CH1 cDNA   ctc tac tcc ctc agc agc acg gtg aca gtg ccc tcc agc agg tgg ... ... ... ccc agc


                                                       _________________________FG_________________________        
                                   
                                   100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                    E   T   F   T   C   N   V   V   H   P   A           S   N   T   K   V   D   K 
  AF354267 IGHG4*01 (F) CH1 cDNA   gag acc ttc acc tgc aac gtg gtc cac ccg gcc ... ... agc aac act aaa gta gac aag


                                           
                                   
                                   120 
                                    P  
  AF354267 IGHG4*01 (F) CH1 cDNA   cca 
                                 
                                 
                                  1   2   3   4   5   6   7   8   9   10  11  12  13  14 
                                  V   P   K   E   S   T   C   K   C   I   S   P   C   P  
  AF354267 IGHG4*01 (F) H cDNA   gtg ccc aaa gag tcc acc tgc aag tgt ata tcc cca tgc cca 
                                                                                                                   
                                   
                                   1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                            V   P   E   S   L   G   G   P   S   V   F   I   F   P   P   K   P   K 
  AF354267 IGHG4*01 (F) CH2 cDNA           gtc cct gaa tca ctg gga ggg cct tcg gtc ttc atc ttt ccc ccg aaa ccc aag


                                               _____AB_____                                            ____________
                                               15.1    15.3                                                        
                                    13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                    D   I   L   R   I       T   R   T   P   E   I   T   C   V   V   L   D   L   G 
  AF354267 IGHG4*01 (F) CH2 cDNA   gac atc ctc agg att ... acc cga aca ccc gag atc acc tgt gtg gtg tta gat ctg ggc


                                   _______BC___________________                            _____________CD_________
                                                                                           45.1    45.3    45.5    
                                    30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                    R   E   D   P   E   V   Q   I   S   W   F   V   D   G   K   E   V   H         
  AF354267 IGHG4*01 (F) CH2 cDNA   cgt gag gac cct gag gtg cag atc agc tgg ttc gtg gat ggt aag gag gtg cac ... ...


                                   ____                                ___________________________DE_______________
                                   45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                        77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                        T   A   K   T   Q   P   R   E   Q   Q   F   N                           S 
  AF354267 IGHG4*01 (F) CH2 cDNA   ... aca gcc aag acg cag cct cgt gag cag cag ttc aac ... ... ... ... ... ... agc


                                   ____________                                                ___EF___            
                                       85.2                                                    96.1                
                                   85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                    T   Y   R   V   V   S   V   L   P   I   E   H   Q   D   W           L   T   G 
  AF354267 IGHG4*01 (F) CH2 cDNA   acc tac cgt gtg gtc agc gtc ctc ccc att gag cac cag gac tgg ... ... ctc acc gga


                                                       _________________________FG_________________________        
                                   
                                   100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                    K   E   F   K   C   R   V   N   H   I   G           L   P   S   P   I   E   R 
  AF354267 IGHG4*01 (F) CH2 cDNA   aag gag ttc aag tgc aga gtc aac cac ata ggc ... ... ctc ccg tcc ccc atc gag agg


                                                           
                                   
                                   120 121 122 123 124 125 
                                    T   I   S   K   A   R  
  AF354267 IGHG4*01 (F) CH2 cDNA   act atc tcc aaa gcc aga 
                                                                                                                       
                                       
                                       1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                        G   Q   A   H   Q   P   S   V   Y   V   L   P   P   S   P   K 
  AF354267 IGHG4*01 (F) CH3-CHS cDNA                   ggg caa gcc cat cag ccc agt gtg tat gtc ctg cca cca tcc cca aag


                                                   _____AB_____                                            ____________
                                                   15.1    15.3                                                        
                                        13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                        E   L   S   S           S   D   T   V   T   L   T   C   L   I   K   D   F   F 
  AF354267 IGHG4*01 (F) CH3-CHS cDNA   gag ttg tca tcc ... ... agt gac acg gtc acc ctg acc tgc ctg atc aaa gac ttc ttc


                                       _______BC___________________                            _____________CD_________
                                                                                               45.1    45.3    45.5    
                                        30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                        P           P   E   I   D   V   E   W   Q   S   N   G   Q   P   E   P   E   S 
  AF354267 IGHG4*01 (F) CH3-CHS cDNA   cca ... ... cct gag att gat gtg gag tgg cag agc aat gga cag ccg gag ccc gag agc


                                       ____                                ___________________________DE_______________
                                       45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                            77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                            K   Y   H   T   T   A   P   Q   L   D   E   D                           G 
  AF354267 IGHG4*01 (F) CH3-CHS cDNA   ... aag tac cac acg act gcg ccc cag ctg gac gag gac ... ... ... ... ... ... ggg


                                       ____________                                                ___EF___            
                                           85.2                                                    96.1                
                                       85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                        S   Y   F   L   Y   S   K   L   S   V   D   K   S   R   W           Q   Q   G 
  AF354267 IGHG4*01 (F) CH3-CHS cDNA   tcc tac ttc ctg tac agc aag ctc tct gtg gac aag agc cgc tgg ... ... cag cag gga


                                                           _________________________FG_________________________        
                                       
                                       100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                        D   T   F   T   C   A   V   M   H   E   A       L   Q   N   H   Y   T   D   L 
  AF354267 IGHG4*01 (F) CH3-CHS cDNA   gac acc ttc aca tgt gcg gtg atg cat gaa gct ... cta cag aac cac tac aca gat cta


                                                                           __CHS___
                                       
                                       120 121 122 123 124 125 126 127 128 129 130 
                                        S   L   S   H   S   P               G   K  
  AF354267 IGHG4*01 (F) CH3-CHS cDNA   tcc ctc tcc cat tct ccg ... ... ... ggt aaa 
  

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
05/05/2015
Last updated:
20/05/2015
Authors:
Saida Hadi-Saljoqi