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When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.


                                                                                                                     
                                     
                                     1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                      A   S   T   T   A   P   S   V   F   P   L   A   P   S   C   G 
  AF354267 IGHG4*01 (F) CH1 cDNA                     gcc tcc acc acg gcc ccc tcg gtt ttc cca ctg gcc ccc agc tgc ggg
                                


                                                 _____AB_____                                            ____________
                                                 15.1    15.3                                                        
                                      13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                      S   T   S               G   S   T   V   A   L   A   C   L   V   S   G   Y   F 
  AF354267 IGHG4*01 (F) CH1 cDNA     tcc act tcc ... ... ... ggc tcc acg gtg gcc ctg gcc tgc ctg gtg tca ggc tac ttc
                                


                                     _______BC___________________                            _____________CD_________
                                                                                             45.1    45.3    45.5    
                                      30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                      P           E   P   V   T   V   S   W   N   S   G   S   L   T   S             
  AF354267 IGHG4*01 (F) CH1 cDNA     ccc ... ... gag cct gta act gtg tcc tgg aat tcc ggc tcc ttg acc agc ... ... ...
                                


                                     ____                                ___________________________DE_______________
                                     45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                          77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                          G   V   H   T   F   P   S   V   L   Q   S   S                           G 
  AF354267 IGHG4*01 (F) CH1 cDNA     ... ggt gtg cac acc ttc ccg tcc gtc ctg cag tcc tca ... ... ... ... ... ... ggg
                                


                                     ____________                                                ___EF___            
                                         85.2                                                    96.1                
                                     85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                      L   Y   S   L   S   S   T   V   T   V   P   S   S   R   W               P   S 
  AF354267 IGHG4*01 (F) CH1 cDNA     ctc tac tcc ctc agc agc acg gtg aca gtg ccc tcc agc agg tgg ... ... ... ccc agc
                                


                                                         _________________________FG_________________________        
                                     
                                     100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                      E   T   F   T   C   N   V   V   H   P   A           S   N   T   K   V   D   K 
  AF354267 IGHG4*01 (F) CH1 cDNA     gag acc ttc acc tgc aac gtg gtc cac ccg gcc ... ... agc aac act aaa gta gac aag
                                


                                         
                                     
                                     120 
                                      P  
  AF354267 IGHG4*01 (F) CH1 cDNA     cca 
                                
                                   
                                   
                                    1   2   3   4   5   6   7   8   9   10  11  12  13  14 
                                    V   P   K   E   S   T   C   K   C   I   S   P   C   P  
  AF354267 IGHG4*01 (F) H cDNA     gtg ccc aaa gag tcc acc tgc aag tgt ata tcc cca tgc cca 
                              
                                                                                                                     
                                     
                                     1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                              V   P   E   S   L   G   G   P   S   V   F   I   F   P   P   K   P   K 
  AF354267 IGHG4*01 (F) CH2 cDNA             gtc cct gaa tca ctg gga ggg cct tcg gtc ttc atc ttt ccc ccg aaa ccc aag
                                


                                                 _____AB_____                                            ____________
                                                 15.1    15.3                                                        
                                      13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                      D   I   L   R   I       T   R   T   P   E   I   T   C   V   V   L   D   L   G 
  AF354267 IGHG4*01 (F) CH2 cDNA     gac atc ctc agg att ... acc cga aca ccc gag atc acc tgt gtg gtg tta gat ctg ggc
                                


                                     _______BC___________________                            _____________CD_________
                                                                                             45.1    45.3    45.5    
                                      30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                      R   E   D   P   E   V   Q   I   S   W   F   V   D   G   K   E   V   H         
  AF354267 IGHG4*01 (F) CH2 cDNA     cgt gag gac cct gag gtg cag atc agc tgg ttc gtg gat ggt aag gag gtg cac ... ...
                                


                                     ____                                ___________________________DE_______________
                                     45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                          77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                          T   A   K   T   Q   P   R   E   Q   Q   F   N                           S 
  AF354267 IGHG4*01 (F) CH2 cDNA     ... aca gcc aag acg cag cct cgt gag cag cag ttc aac ... ... ... ... ... ... agc
                                


                                     ____________                                                ___EF___            
                                         85.2                                                    96.1                
                                     85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                      T   Y   R   V   V   S   V   L   P   I   E   H   Q   D   W           L   T   G 
  AF354267 IGHG4*01 (F) CH2 cDNA     acc tac cgt gtg gtc agc gtc ctc ccc att gag cac cag gac tgg ... ... ctc acc gga
                                


                                                         _________________________FG_________________________        
                                     
                                     100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                      K   E   F   K   C   R   V   N   H   I   G           L   P   S   P   I   E   R 
  AF354267 IGHG4*01 (F) CH2 cDNA     aag gag ttc aag tgc aga gtc aac cac ata ggc ... ... ctc ccg tcc ccc atc gag agg
                                


                                                             
                                     
                                     120 121 122 123 124 125 
                                      T   I   S   K   A   R  
  AF354267 IGHG4*01 (F) CH2 cDNA     act atc tcc aaa gcc aga 
                                
                                                                                                                         
                                         
                                         1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                          G   Q   A   H   Q   P   S   V   Y   V   L   P   P   S   P   K 
  AF354267 IGHG4*01 (F) CH3-CHS cDNA                     ggg caa gcc cat cag ccc agt gtg tat gtc ctg cca cca tcc cca aag
                                    


                                                     _____AB_____                                            ____________
                                                     15.1    15.3                                                        
                                          13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                          E   L   S   S           S   D   T   V   T   L   T   C   L   I   K   D   F   F 
  AF354267 IGHG4*01 (F) CH3-CHS cDNA     gag ttg tca tcc ... ... agt gac acg gtc acc ctg acc tgc ctg atc aaa gac ttc ttc
                                    


                                         _______BC___________________                            _____________CD_________
                                                                                                 45.1    45.3    45.5    
                                          30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                          P           P   E   I   D   V   E   W   Q   S   N   G   Q   P   E   P   E   S 
  AF354267 IGHG4*01 (F) CH3-CHS cDNA     cca ... ... cct gag att gat gtg gag tgg cag agc aat gga cag ccg gag ccc gag agc
                                    


                                         ____                                ___________________________DE_______________
                                         45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                              77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                              K   Y   H   T   T   A   P   Q   L   D   E   D                           G 
  AF354267 IGHG4*01 (F) CH3-CHS cDNA     ... aag tac cac acg act gcg ccc cag ctg gac gag gac ... ... ... ... ... ... ggg
                                    


                                         ____________                                                ___EF___            
                                             85.2                                                    96.1                
                                         85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                          S   Y   F   L   Y   S   K   L   S   V   D   K   S   R   W           Q   Q   G 
  AF354267 IGHG4*01 (F) CH3-CHS cDNA     tcc tac ttc ctg tac agc aag ctc tct gtg gac aag agc cgc tgg ... ... cag cag gga
                                    


                                                             _________________________FG_________________________        
                                         
                                         100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                          D   T   F   T   C   A   V   M   H   E   A       L   Q   N   H   Y   T   D   L 
  AF354267 IGHG4*01 (F) CH3-CHS cDNA     gac acc ttc aca tgt gcg gtg atg cat gaa gct ... cta cag aac cac tac aca gat cta
                                    


                                                                             __CHS___
                                         
                                         120 121 122 123 124 125 126 127 128 129 130 
                                          S   L   S   H   S   P               G   K  
  AF354267 IGHG4*01 (F) CH3-CHS cDNA     tcc ctc tcc cat tct ccg ... ... ... ggt aaa 
                                    

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
05/05/2015
Last updated:
20/05/2015
Authors:
Saida Hadi-Saljoqi