Here you are: IMGT Web resources > IMGT Repertoire > Proteins and alleles

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.


                                                                                                                      
                                      
                                      1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                       X   S   P   S   P   P   N   L   F   P   L   I   T   C   E   N 
  IMGT000001   IGHM*01 F CH1 gDNA                     nag agt cca tcc cct cca aac ctc ttc ccc ctc atc acc tgt gag aac

                                                                                                                     
  AAEX03006126 IGHM*01 F CH1 gDNA                      -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---



                                                  _____AB_____                                            ____________
                                                  15.1    15.3                                                        
                                       13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                       S   L   S   D           E   T   L   V   A   M   G   C   L   A   R   D   F   L 
  IMGT000001   IGHM*01 F CH1 gDNA     tcc ctg tcc gat ... ... gag acc ctc gtg gcc atg ggc tgc ctg gcc cgg gac ttc ctg

                                                                                                                     
  AAEX03006126 IGHM*01 F CH1 gDNA     --- --- --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---



                                      _______BC___________________                            _____________CD_________
                                                                                              45.1    45.3    45.5    
                                       30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                       P           G   S   I   T   F   S   W   K   Y   E   N   L   S   A   I   N     
  IMGT000001   IGHM*01 F CH1 gDNA     cct ... ... ggc tcc atc acc ttc tcc tgg aag tac gag aac ctc agt gca atc aac ...

                                                                                                                     
  AAEX03006126 IGHM*01 F CH1 gDNA     --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ...



                                      ____                                ___________________________DE_______________
                                      45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                           77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                           N   Q   D   I   K   T   F   P   S   V   L   R   E                       G 
  IMGT000001   IGHM*01 F CH1 gDNA     ... aac cag gac att aag acc ttc cct tca gtt ctg aga gag ... ... ... ... ... ggc

                                                                                                                     
  AAEX03006126 IGHM*01 F CH1 gDNA     ... --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ---



                                      ____________                                                ___EF___            
                                          85.2                                                    96.1                
                                      85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                       K   Y   V   A   T   S   Q   V   F   L   P   S   V   D   I   I   Q   G   S   D 
  IMGT000001   IGHM*01 F CH1 gDNA     aag tat gtg gcg acc tct cag gtg ttc ctg ccc tcc gtg gac atc atc cag ggt tca gac

                                                                                                                     
  AAEX03006126 IGHM*01 F CH1 gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---



                                                          _________________________FG_________________________        
                                      
                                      100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                       E   Y   I   T   C   N   V   K   H   S                   N   G   D   K   S   V 
  IMGT000001   IGHM*01 F CH1 gDNA     gag tac atc aca tgc aac gtc aag cac tcc ... ... ... ... aat ggt gac aaa tct gtg

                                                                                                                     
  AAEX03006126 IGHM*01 F CH1 gDNA     --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- --- --- --- --- ---



                                                          
                                      
                                      120 121 122 123 124 
                                       N   V   P   I   T  
  IMGT000001   IGHM*01 F CH1 gDNA     aac gtg ccc atc aca 

                                                          
  AAEX03006126 IGHM*01 F CH1 gDNA     --- --- --- --- --- g

                                                                                                                      
                                      
                                      1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                   G   P   V   P   T   S   P   N   V   T   V   F   I   P   P   R   D 
  IMGT000001   IGHM*01 F CH2 gDNA                 ggg cct gta cca acg tct ccc aac gtg act gtc ttc atc cca ccc cgc gac

                                                                                                                     
  AAEX03006126 IGHM*01 F CH2 gDNA                  -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---



                                                  _____AB_____                                            ____________
                                                  15.1    15.3                                                        
                                       13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                       A   F   S   G   N   G   Q   R   K   S   Q   L   I   C   Q   A   A   G   F   S 
  IMGT000001   IGHM*01 F CH2 gDNA     gcc ttc tct ggc aat ggc cag cgc aag tcc cag ctc atc tgc cag gct gca ggt ttc agc

                                                                                                                     
  AAEX03006126 IGHM*01 F CH2 gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---



                                      _______BC___________________                            _____________CD_________
                                                                                              45.1    45.3    45.5    
                                       30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                       P           K   Q   I   S   V   S   W   F   R   D   G   K   Q   I   E   S     
  IMGT000001   IGHM*01 F CH2 gDNA     ccc ... ... aag cag att tcc gtg tct tgg ttc cgt gat gga aag cag att gag tct ...

                                                                                                                     
  AAEX03006126 IGHM*01 F CH2 gDNA     --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ...



                                      ____                                ___________________________DE_______________
                                      45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                           77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                           G   F   N   T   G   K   A   E   A   E   E   K   E   H           G   P   V 
  IMGT000001   IGHM*01 F CH2 gDNA     ... ggc ttc aac aca ggg aag gca gag gcc gag gag aaa gag cat ... ... ggg cct gtg

                                                                                                                     
  AAEX03006126 IGHM*01 F CH2 gDNA     ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---



                                      ____________                                                ___EF___            
                                          85.2                                                    96.1                
                                      85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                       T   Y   S   I   L   S   M   L   T   I   T   E   S   A   W           L   S   Q 
  IMGT000001   IGHM*01 F CH2 gDNA     acc tac agc atc ctc agc atg ctg acc atc acc gag agt gcc tgg ... ... ctc agc cag

                                                                                                                     
  AAEX03006126 IGHM*01 F CH2 gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---



                                                          _________________________FG_________________________        
                                      
                                      100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                       S   V   F   T   C   H   V   E   H   N                   G   I   I   F   Q   K 
  IMGT000001   IGHM*01 F CH2 gDNA     agc gtg ttc acc tgc cac gtg gag cac aat ... ... ... ... ggg atc atc ttc cag aag

                                                                                                                     
  AAEX03006126 IGHM*01 F CH2 gDNA     --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- --- --- --- --- ---



                                                                      
                                      
                                      120 121 122 123 124 125 126 127 
                                       N   V   S   S   M   C   T   S  
  IMGT000001   IGHM*01 F CH2 gDNA     aac gtg tcc tcc atg tgc acc tcc 

                                                                      
  AAEX03006126 IGHM*01 F CH2 gDNA     --- --- --- --- --- --- --- --- a

                                                                                                                      
                                      
                                      1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                       N   T   P   V   G   I   S   I   F   T   I   P   P   S   F   A 
  IMGT000001   IGHM*01 F CH3 gDNA                     aat aca ccc gtt ggc atc agc atc ttc acc atc ccc ccc tcc ttt gcc

                                                                                                                     
  AAEX03006126 IGHM*01 F CH3 gDNA                      -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---



                                                  _____AB_____                                            ____________
                                                  15.1    15.3                                                        
                                       13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                       S   I   F   N           T   K   S   A   K   L   S   C   L   V   T   D   L   A 
  IMGT000001   IGHM*01 F CH3 gDNA     agc atc ttc aac ... ... acc aag tca gcc aag ctg tcc tgc ctg gtc act gac ctg gcc

                                                                                                                     
  AAEX03006126 IGHM*01 F CH3 gDNA     --- --- --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---



                                      _______BC___________________                            _____________CD_________
                                                                                              45.1    45.3    45.5    
                                       30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                       T   Y       D   S   L   T   I   S   W   T   R   Q   N   G   E   A   L         
  IMGT000001   IGHM*01 F CH3 gDNA     act tat ... gac agc ctg acc atc tcc tgg acc cgt cag aat ggc gag gct ctg ... ...

                                                                                                                     
  AAEX03006126 IGHM*01 F CH3 gDNA     --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ...



                                      ____                                ___________________________DE_______________
                                      45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                           77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                           K   T   H   T   N   I   S   E   S   H   P   N                           N 
  IMGT000001   IGHM*01 F CH3 gDNA     ... aaa acc cac acc aac atc tct gag agc cat ccc aac ... ... ... ... ... ... aac

                                                                                                                     
  AAEX03006126 IGHM*01 F CH3 gDNA     ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---



                                      ____________                                                ___EF___            
                                          85.2                                                    96.1                
                                      85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                       T   F   S   A   M   G   E   A   T   V   C   V   E   E   W           E   S   G 
  IMGT000001   IGHM*01 F CH3 gDNA     acc ttc agt gcc atg ggg gaa gcc act gtc tgc gtg gag gaa tgg ... ... gag tca ggc

                                                                                                                     
  AAEX03006126 IGHM*01 F CH3 gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---



                                                          _________________________FG_________________________        
                                      
                                      100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                       E   Q   F   T   C   T   V   T   H   T   D           L   P   S   P   L   K   K 
  IMGT000001   IGHM*01 F CH3 gDNA     gag cag ttc acc tgc aca gtg acc cac aca gat ... ... ctg ccc tca ccg ctg aag aag

                                                                                                                     
  AAEX03006126 IGHM*01 F CH3 gDNA     --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- --- ---



                                                              
                                      
                                      120 121 122 123 124 125 
                                       T   I   S   R   P   K  
  IMGT000001   IGHM*01 F CH3 gDNA     acc atc tcc agg ccc aag 

                                                              
  AAEX03006126 IGHM*01 F CH3 gDNA     --- --- --- --- --- --- g

                                                                                                                          
                                          
                                          1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                       D   V   N   K   H   M   P   S   V   Y   V   L   P   P   S   R   E 
  IMGT000001   IGHM*01 F CH4-CHS gDNA                 gat gtc aac aag cac atg cct tct gtc tac gtc ctg ccc ccg agc cgg gag

                                                                                                                         
  AAEX03006126 IGHM*01 F CH4-CHS gDNA                  -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---



                                                      _____AB_____                                            ____________
                                                      15.1    15.3                                                        
                                           13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                           Q   L   S   L           R   E   S   A   S   L   T   C   L   V   K   G   F   S 
  IMGT000001   IGHM*01 F CH4-CHS gDNA     cag ctg agc ctg ... ... cgg gaa tcg gcc tca ctc acc tgc ctg gtg aaa ggc ttc tca

                                                                                                                         
  AAEX03006126 IGHM*01 F CH4-CHS gDNA     --- --- --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---



                                          _______BC___________________                            _____________CD_________
                                                                                                  45.1    45.3    45.5    
                                           30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                           P           P   D   V   F   V   Q   W   L   Q   K   G   Q   P   V   P   P   D 
  IMGT000001   IGHM*01 F CH4-CHS gDNA     ccc ... ... cca gat gtg ttc gtg cag tgg ctg cag aag ggc cag ccc gtg ccc cct gac

                                                                                                                         
  AAEX03006126 IGHM*01 F CH4-CHS gDNA     --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---



                                          ____                                ___________________________DE_______________
                                          45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                               77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                               S   Y   V   T   S   A   P   M   P   E   P   Q   A                   P   G 
  IMGT000001   IGHM*01 F CH4-CHS gDNA     ... agc tac gtg acc agc gcc ccg atg ccc gag ccc caa gcc ... ... ... ... ccc ggc

                                                                                                                         
  AAEX03006126 IGHM*01 F CH4-CHS gDNA     ... --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- ---



                                          ____________                                                ___EF___            
                                              85.2                                                    96.1                
                                          85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                           L   Y   F   V   H   S   I   L   T   V   S   E   E   D   W           N   A   G 
  IMGT000001   IGHM*01 F CH4-CHS gDNA     ctc tac ttt gtc cac agc atc ctg acc gtg agt gag gag gac tgg ... ... aat gcc ggg

                                                                                                                         
  AAEX03006126 IGHM*01 F CH4-CHS gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---



                                                              _________________________FG_________________________        
                                          
                                          100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                           E   T   Y   T   C   V   V   G   H   E   A       L   P   H   V   V   T   E   R 
  IMGT000001   IGHM*01 F CH4-CHS gDNA     gag acc tac acc tgt gtt gta ggc cat gag gcc ... ctg ccc cat gtg gtg acc gag agg

                                                                                                                         
  AAEX03006126 IGHM*01 F CH4-CHS gDNA     --- --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- ---



                                                                              ______________________________________CHS___
                                          
                                          120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 
                                           S   V   D   K   S   T               G   K   P   T   L   Y   N   V   S   L   V 
  IMGT000001   IGHM*01 F CH4-CHS gDNA     agc gtg gac aag tcc acc ... ... ... ggt aaa ccc acc ttg tac aac gtg tcc ctg gtc

                                                                                                                         
  AAEX03006126 IGHM*01 F CH4-CHS gDNA     --- --- --- --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- ---



                                          ____________________________________
                                          
                                          140 141 142 143 144 145 146 147 148 
                                           L   S   D   T   A   S   T   C   Y  
  IMGT000001   IGHM*01 F CH4-CHS gDNA     tta tct gac aca gcc agc acc tgc tac 

                                                                              
  AAEX03006126 IGHM*01 F CH4-CHS gDNA     --- --- --- --- --- --- --- --- --- 

                                        
                                        
                                         1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                         G   G   E   V   S   A   E   E   E   G   F   E   N   L   N   T   M   A   S   T 
  IMGT000001   IGHM*01 F M1+M2 gDNA     ggg ggg gag gtg agt gcc gag gag gaa ggc ttc gag aac ctg aat acc atg gca tcc acc

                                                                                                                       
  AAEX03006126 IGHM*01 F M1+M2 gDNA      -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---



                                        
                                        
                                         21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40 
                                         F   I   V   L   F   L   L   S   V   F   Y   S   T   T   V   T   L   F   K   V 
  IMGT000001   IGHM*01 F M1+M2 gDNA     ttc atc gtc ctc ttc ctc ctc agt gtc ttc tac agc acc aca gtc act ctg ttc aag gtg

                                                                                                                       
  AAEX03006126 IGHM*01 F M1+M2 gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---



                                        
                                        
                                         41 
                                         K  
  IMGT000001   IGHM*01 F M1+M2 gDNA     aaa 

                                            
  AAEX03006126 IGHM*01 F M1+M2 gDNA     --- 


This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux, Mehdi Yousfi and Perrine Pégorier).

Created:
05/05/2015
Last updated:
17/05/2018
Authors:
Géraldine Folch and Saida Hadi-Saljoqi