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When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

                                                                                                                                       
                                               
                                                1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                                N   T   E   V   I   Q   T   P   R   R   K   V   T   T   M   G   Q   E   V   T 
  IMGT000005   TRBV12-1*01 P V-REGION gDNA     aat act gaa gtc atc cag aca ccc agg cgc aag gtg aca acg atg gga caa gaa gta act
                                          
                                                                                                                              
  AAEX02035466 TRBV12-1*01 P V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                          


                                                                       ___________________CDR1-IMGT____________________        
                                               
                                                21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40 
                                                L   G   *   E   L   T   S   G   H                               Y   T   L   F 
  IMGT000005   TRBV12-1*01 P V-REGION gDNA     ctg gga tga gag ctt act tct ggc cat ... ... ... ... ... ... ... tat acc ctt ttc
                                          
                                                                                                                              
  AAEX02035466 TRBV12-1*01 P V-REGION gDNA     --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ... --- --- --- ---
                                          


                                                                                                           _______________CDR2-
                                               
                                                41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60 
                                                W   Y   R   Q   T   S   G   K   E   P   K   L   L   I   Y   F   S   N         
  IMGT000005   TRBV12-1*01 P V-REGION gDNA     tgg tac aga cag acc tca ggg aag gaa cca aag ctg ctg att tac ttc agc aat ... ...
                                          
                                                                                                                              
  AAEX02035466 TRBV12-1*01 P V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ...
                                          


                                               IMGT________________                                                            
                                               
                                                61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79  80 
                                                        K   A   L   M   D   D   S   G   M   P   K   E   R   F   S   A   E   M 
  IMGT000005   TRBV12-1*01 P V-REGION gDNA     ... ... aaa gct ctt atg gat gac tcg ggg atg ccc aag gaa cgg ttc tca gca gag atg
                                          
                                                                                                                              
  AAEX02035466 TRBV12-1*01 P V-REGION gDNA     ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                          


                                                                                                                               
                                               
                                                81  82  83  84  85  86  87  88  89 89A 89B  90  91  92  93  94  95  96  97  98 
                                                P       D   D   S   F   S   I   L           K   I   Q   P   T   E   P   R   D 
  IMGT000005   TRBV12-1*01 P V-REGION gDNA     cct ... gat gat tca ttc tcc atc ctg ... ... aag atc cag cca aca gaa ccc agg gac
                                          
                                                                                                                              
  AAEX02035466 TRBV12-1*01 P V-REGION gDNA     --- ... --- --- --- --- --- --- --- ... ... --- --- --- --- --- --- --- --- ---
                                          


                                                                       _____CDR3-IMGT______
                                               
                                                99 100 101 102 103 104 105 106 107 108 
                                                S   A   T   Y   L   C   G   S   R   V  
  IMGT000005   TRBV12-1*01 P V-REGION gDNA     tca gcc acg tac cta tgt ggc agc agg gta ga
                                          
                                                                                       
  AAEX02035466 TRBV12-1*01 P V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --
                                          



Legend:
*: STOP_CODON mutation

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
06/10/2017
Authors:
Perrine Pégorier