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When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

                                                                                                                                      
                                              
                                               1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                               D   T   G   I   T   Q   T   P   K   H   L   L   T   E   T   G   R   R   V   T 
  IMGT000005   TRBV4-4*01 F V-REGION gDNA     gac act gga att acc cag acc ccc aaa cac ctg tta aca gag aca ggg agg aga gtg acc
                                         
                                                                                                                             
  AAEX02035466 TRBV4-4*01 F V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                         


                                                                      ___________________CDR1-IMGT____________________        
                                              
                                               21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40 
                                               L   K   C   E   Q   H   L   G   H                               N   A   V   Y 
  IMGT000005   TRBV4-4*01 F V-REGION gDNA     ctc aag tgt gaa caa cat ctg gga cat ... ... ... ... ... ... ... aat gct gtg tac
                                         
                                                                                                                             
  AAEX02035466 TRBV4-4*01 F V-REGION gDNA     --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ... --- --- --- ---
                                         


                                                                                                          _______________CDR2-
                                              
                                               41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60 
                                               W   Y   Q   Q   S   T   Q   K   P   P   K   L   M   F   A   Y   S   Y         
  IMGT000005   TRBV4-4*01 F V-REGION gDNA     tgg tat caa cag agc act cag aag cca cca aag ctc atg ttt gcc tac agt tac ... ...
                                         
                                                                                                                             
  AAEX02035466 TRBV4-4*01 F V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ...
                                         


                                              IMGT________________                                                            
                                              
                                               61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79  80 
                                                       K   V   L   V   E   N   E   T   A   S       G   R   F   S   P   E   C 
  IMGT000005   TRBV4-4*01 F V-REGION gDNA     ... ... aag gta ctc gtt gaa aat gag act gct tct ... ggt cgc ttc tca cct gag tgc
                                         
                                                                                                                             
  AAEX02035466 TRBV4-4*01 F V-REGION gDNA     ... ... --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---
                                         


                                                                                                                              
                                              
                                               81  82  83  84  85  86  87  88  89 89A 89B  90  91  92  93  94  95  96  97  98 
                                               P       D   S   S   R   F   Y   L           H   M   D   A   L   E   P   N   D 
  IMGT000005   TRBV4-4*01 F V-REGION gDNA     cca ... gac agc tcc agg ttc tac ctt ... ... cac atg gat gcc ctg gag ccc aat gac
                                         
                                                                                                                             
  AAEX02035466 TRBV4-4*01 F V-REGION gDNA     --- ... --- --- --- --- --- --- --- ... ... --- --- --- --- --- --- --- --- ---
                                         


                                                                      _____CDR3-IMGT______
                                              
                                               99 100 101 102 103 104 105 106 107 108 
                                               S   A   L   Y   L   C   A   S   K   E  
  IMGT000005   TRBV4-4*01 F V-REGION gDNA     tct gcc ttg tat ctc tgt gct agc aaa gaa a
                                         
                                                                                      
  AAEX02035466 TRBV4-4*01 F V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- -

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
06/10/2017
Authors:
Perrine Pégorier