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When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

	
	
	                                                                                
                                     
                                     1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                      A   S   T   K   G   P   S   V   F   P   L   V   P   S   S   R 
  X06766   IGHGP*01  ORF  CH1 gDNA                   gcc tcc acc aag ggc cca tcg gtc ttc ccc ctg gtg ccc tcc tcc agg
                                                                                                                    
  AL928769 IGHGP*02  ORF  CH1 gDNA                   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                 _____AB_____                                            ____________
                                                 15.1    15.3                                                        
                                      13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                      S   V   S               E   G   T   A   A   L   G   C   L   V   K   D   Y   F 
  X06766   IGHGP*01  ORF  CH1 gDNA   agc gtc tct ... ... ... gag ggc aca gcg gcc ctg ggc tgc ctg gtc aag gac tac ttc
                                                                                                                    
  AL928769 IGHGP*02  ORF  CH1 gDNA   --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                     _______BC___________________                            _____________CD_________
                                                                                             45.1    45.3    45.5    
                                      30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                      P           E   P   V   T   V   S   W   N   S   G   A   L   T   R             
  X06766   IGHGP*01  ORF  CH1 gDNA   ccc ... ... gaa ccg gtg acg gtg tcg tgg aac tca ggg gcc ctg acc aga ... ... ...
                                                                                                                    
  AL928769 IGHGP*02  ORF  CH1 gDNA   --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ...


                                     ____                                ___________________________DE_______________
                                     45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                          77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                          S   V   H   T   F   P   A   V   L   Q   S   S                           G 
  X06766   IGHGP*01  ORF  CH1 gDNA   ... agc gtg cac acc ttc ccg gct gtc cta cag tcc tca ... ... ... ... ... ... gga
                                                                                                                    
  AL928769 IGHGP*02  ORF  CH1 gDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---


                                     ____________                                                ___EF___            
                                         85.2                                                    96.1                
                                     85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                      L   Y   S   L   S   S   V   V   T   V   P   S   S   S   L               G   T 
  X06766   IGHGP*01  ORF  CH1 gDNA   ctc tac tcc ctc agc agc gtg gtg acc gtg ccc tcc agc agc ttg ... ... ... ggc acc
                                                                                                                    
  AL928769 IGHGP*02  ORF  CH1 gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... --- ---


                                                         _________________________FG_________________________        
                                     
                                     100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                      Q   T   Y   T   C   N   V   D   H   K   P           S   N   T   K   V   D   K 
  X06766   IGHGP*01  ORF  CH1 gDNA   cag acc tac acc tgc aac gta gat cac aag ccc ... ... agc aac acc aag gtg gac aag
                                                                                                                    
  AL928769 IGHGP*02  ORF  CH1 gDNA   --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- --- ---


                                             
                                     
                                     120 121 
                                      T   V  
  X06766   IGHGP*01  ORF  CH1 gDNA   aca gtt 
                                             
  AL928769 IGHGP*02  ORF  CH1 gDNA   --- --- 




                                  
                                   
                                    1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17 
                                    E   P   K   T   P   C   C   D   T   T   H   T   C   P   P   C   A  
  X06766   IGHGP*01  ORF  H gDNA   gag ccc aaa acc cca tgt tgt gac aca act cac aca tgc cca cca tgt gca 
                                                                                                       
  AL928769 IGHGP*02  ORF  H gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- 





                                                                                                                     
                                     
                                     1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                              T   T   E   P   L   G   G   P   S   V   F   L   F   P   P   K   P   K 
  X06766   IGHGP*01  ORF  CH2 gDNA           aca act gaa ccc ctg ggg gga ccg tca gtc ttc ctc ttc ccc cca aaa ccc aag
                                                                                                                    
  AL928769 IGHGP*02  ORF  CH2 gDNA           --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                 _____AB_____                                            ____________
                                                 15.1    15.3                                                        
                                      13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                      D   T   L   M   I       S   R   T   P   E   V   T   C   V   V   V   D   V   S 
  X06766   IGHGP*01  ORF  CH2 gDNA   gat acc ctc atg atc ... tcc cgg acc cct gag gtc acg tgc gtg gtg gtg gac gtg agc
                                                                                                                    
  AL928769 IGHGP*02  ORF  CH2 gDNA   --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                     _______BC___________________                            _____________CD_________
                                                                                             45.1    45.3    45.5    
                                      30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                      H   E   D   P   E   V   K   F   N   W   Y   V   D   G   V   E   V   H         
  X06766   IGHGP*01  ORF  CH2 gDNA   cac gaa gac cct gag gtc aag ttc aac tgg tac gtg gac ggc gtg gag gtg cat ... ...
                                                                                                                    
  AL928769 IGHGP*02  ORF  CH2 gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ...


                                     ____                                ___________________________DE_______________
                                     45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                          77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                          N   A   K   T   K   P   W   E   E   Q   Y   N                           S 
  X06766   IGHGP*01  ORF  CH2 gDNA   ... aat gcc aag aca aag ccg tgg gag gag cag tac aac ... ... ... ... ... ... agc
                                                                                                                    
  AL928769 IGHGP*02  ORF  CH2 gDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---


                                     ____________                                                ___EF___            
                                         85.2                                                    96.1                
                                     85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                      T   Y   H   V   V   S   V   L   T   V   V   H   Q   N   W           L   N   G 
  X06766   IGHGP*01  ORF  CH2 gDNA   acg tac cat gtg gtc agc gtc ctc acc gtc gtg cac cag aac tgg ... ... ctg aac ggc
                                                                                                                    
  AL928769 IGHGP*02  ORF  CH2 gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---


                                                         _________________________FG_________________________        
                                     
                                     100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                      R   E   Y   K   C   K   V   S   N   K   G           L   P   A   P   I   E   K 
  X06766   IGHGP*01  ORF  CH2 gDNA   agg gag tac aag tgc aag gtc tcc aac aaa ggc ... ... ctc cca gcc ccc atc gag aaa
                                      K                                                                             
  AL928769 IGHGP*02  ORF  CH2 gDNA   -a- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- --- --- ---


                                                             
                                     
                                     120 121 122 123 124 125 
                                      T   I   S   K   T   K  
  X06766   IGHGP*01  ORF  CH2 gDNA   acc atc tcc aaa acc aaa 
                                                             
  AL928769 IGHGP*02  ORF  CH2 gDNA   --- --- --- --- --- --- 





                                                                                                                         
                                         
                                         1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                          G   Q   P   R   E   P   Q   V   Y   T   L   P   P   S   Q   K 
  X06766   IGHGP*01  ORF  CH3-CHS gDNA                   ggg cag ccc cga gaa cca cag gtg tac acc ctg ccc cca tcc cag aag
                                                                                                                        
  AL928769 IGHGP*02  ORF  CH3-CHS gDNA                   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                     _____AB_____                                            ____________
                                                     15.1    15.3                                                        
                                          13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                              M   T               K   N   Q   V   T   L   T   C   L   V   K   G   F   Y 
  X06766   IGHGP*01  ORF  CH3-CHS gDNA   ... atg acc ... ... ... aag aac cag gtc acc ctg acc tgc ctg gtc aaa ggc ttc tac
                                                                                              L  
  AL928769 IGHGP*02  ORF  CH3-CHS gDNA   ... --- --- ... ... ... --- --- --- --- --- --- --- ctt tc


                                         _______BC___________________                            _____________CD_________
                                                                                                 45.1    45.3    45.5    
                                          30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                          P           S   D   I   T   V   E   W   E   S   N   G   Q   P   E   N         
  X06766   IGHGP*01  ORF  CH3-CHS gDNA   ccc ... ... agc gac atc acc gtg gag tgg gag agc aat ggg cag ccg gag aac ... ...
   


                                         ____                                ___________________________DE_______________
                                         45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                              77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                              N   Y   K   T   T   P   P   M   L   D   S   N                           G 
  X06766   IGHGP*01  ORF  CH3-CHS gDNA   ... aac tac aag acc acg cct ccc atg ctg gac tcc aac ... ... ... ... ... ... ggc
   


                                         ____________                                                ___EF___            
                                             85.2                                                    96.1                
                                         85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                          S   F   F   L   Y   S   K   L   T   V   D   K   S   R   W           Q   Q   G 
  X06766   IGHGP*01  ORF  CH3-CHS gDNA   tcc ttc ttc ctc tat agc aag ctc acc gtg gac aag agc agg tgg ... ... cag cag ggg
   


                                                             _________________________FG_________________________        
                                         
                                         100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                          N   V   F   S   C   S   V   M   H   E   G       L   H   N   H   Y   T   Q   K 
  X06766   IGHGP*01  ORF  CH3-CHS gDNA   aac gtc ttc tca tgc tcc gtg atg cat gag ggt ... ctg cac aac cac tac acg cag aag




                                                                             __CHS___
                                         
                                         120 121 122 123 124 125 126 127 128 129 130 
                                          S   L   S   L   S   P               G   K  
  X06766   IGHGP*01  ORF  CH3-CHS gDNA   agc ctc tcc ctg tcc ccg ... ... ... ggt aaa 





                                    
                                    
                                     1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                     E   L   Q   L   E   E   S   C   A   E   A   Q   D   G   E   L   D   G   L   W 
  X52849   IGHGP*01  ORF  M1 gDNA   gag ctg caa ctg gag gag agc tgt gcg gag gcg cag gac ggg gag ctg gac ggg ctg tgg


                                    
                                    
                                     21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40 
                                     T   T   I   T   I   F   I   T   L   F   L   L   S   V   C   Y   S   A   T   V 
  X52849   IGHGP*01  ORF  M1 gDNA   acg acc atc acc atc ttc atc aca ctc ttc ctg cta agc gtg tgc tac agt gcc acc gtc


                                    
                                    
                                     41  42  43  44 
                                     T   F   F   K  
  X52849   IGHGP*01  ORF  M1 gDNA   acc ttc ttc aag 





                                    
                                    
                                     1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                     V   K   W   I   F   S   S   V   V   D   L   K   Q   T   I   V   P   D   Y   R 
  X52848   IGHGP*01  ORF  M2 gDNA   gtg aag tgg atc ttc tcc tcg gtg gtg gac ctg aag cag acc atc gtc ccc gac tac agg


                                    
                                    
                                     21  22  23  24  25  26  27 
                                     N   M   I   G   Q   G   A  
  X52848   IGHGP*01  ORF  M2 gDNA   aac atg atc ggg cag ggg gcc 

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
20/01/1999
Last updated:
27/05/2016
Authors:
Saida Saljoqi, Christèle Martinez-Jean and Nathalie Bosc