Here you are: IMGT Web resources > IMGT Repertoire > Proteins and alleles

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

	
	
	                                                                                 
                                    
                                  1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                   X   S   P   T   R   P   K   V   F   P   L   S   L   E   G   T 
  X53705   IGHA*01 F   CH1 gDNA                   nca tcc ccg acc aga ccc aag gtc ttc ccg ctg agc ctc gag ggc acc
                                                                                                                 
  X53389   IGHA*01 F   CH1 gDNA                   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                              _____AB_____                                            ____________
                                              15.1    15.3                                                        
                                   13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                   Q                       S   D   N   V   V   V   A   C   L   V   Q   G   F   F 
  X53705   IGHA*01 F   CH1 gDNA   cag ... ... ... ... ... tca gat aac gtg gtc gtc gcc tgc ctg gtc cag ggc ttc ttc
                                                                                                                 
  X53389   IGHA*01 F   CH1 gDNA   --- ... ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                  _______BC___________________                            _____________CD_________
                                                                                          45.1    45.3    45.5    
                                   30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                   P   Q       E   P   L   N   V   T   W   S   K   S   G   A   G   V             
  X53705   IGHA*01 F   CH1 gDNA   ccc cag ... gag cca ctc aac gtg acc tgg agc aaa agc gga gcg ggc gtg ... ... ...
                                                                                                                 
  X53389   IGHA*01 F   CH1 gDNA   --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ...


                                  ____                                ___________________________DE_______________
                                  45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                       77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                       T   V   I   N   F   P   P   S   Q   D   A   S   G                       G 
  X53705   IGHA*01 F   CH1 gDNA   ... acc gtc ata aac ttc ccg ccc agc cag gac gcc tcc ggg ... ... ... ... ... ggc
                                                                                                                 
  X53389   IGHA*01 F   CH1 gDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ---


                                  ____________                                                ___EF___            
                                      85.2                                                    96.1                
                                  85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                   L   Y   T   T   S   S   Q   L   T   L   P   A   A   Q   C           P   A   R 
  X53705   IGHA*01 F   CH1 gDNA   ctg tac acc acg agc agc cag ctg acc ctg ccg gcc gca cag tgc ... ... cca gcc agg
                                                                                                                 
  X53389   IGHA*01 F   CH1 gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---


                                                      _________________________FG_________________________        
                                    
                                  100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                   E   S   V   T   C   H   V   E   H   Y               T   N   P   S   Q   D   V 
  X53705   IGHA*01 F   CH1 gDNA   gag tcc gtg aca tgc cac gtg gag cac tac ... ... ... acg aat ccc agc cag gat gtg
                                                                                                                 
  X53389   IGHA*01 F   CH1 gDNA   --- --- --- --- --- --- --- --- --- --- ... ... ... --- --- --- --- --- --- ---


                                                  
                                    
                                  120 121 122 123 
                                   A   V   P   C  
  X53705   IGHA*01 F   CH1 gDNA   gcc gtg ccc tgc 
                                                  
  X53389   IGHA*01 F   CH1 gDNA   --- --- --- --- 
                                      
                                      
                                 1   2   3   4   5   6   7   8   9   10    
                                 V   S   E   T   K   P   C   L                          
  X53705   IGHA*01 F   H gDNA   gtt tcc gaa acc aag cct tgc tta 

  X53389   IGHA*01 F   H gDNA   --- --- --- --- --- --- --- --- 
                                     P   P   P   N   S                                                  
  AB013758 IGHA*02 F   H gDNA   --- c-- cc- c-- --c t-- --- ---
                                     P   P   I   T       P   C   P   S     
  AB013764 IGHA*03 F   H gDNA   --- c-- cc- -t- -ca --c cca -gt ccc tca


                                                                                
                                
                                     1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                              C   D   K   P   R   L   S   L   R   R   P   A   L   E 
  X53705   IGHA*01 F   CH2 gDNA                              tgt gac aaa ccc cga ctg tca ctg cgc cgg ccg gcc ctc gag

  X53389   IGHA*01 F   CH2 gDNA                              --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                       
  AB013758 IGHA*02 F   CH2 gDNA                              --- --- --- --- --
                                                              C   E      
  AB013764 IGHA*03 F   CH2 gDNA                              --c tg- g-g --- --


                                                 _____AB_____                                            ____________
                                                 15.1    15.3                                                        
                                      13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                      D   L   L   L           G   S   E   A   N   L   T   C   T   L   T   G   L   R 
  X53705   IGHA*01 F   CH2 gDNA      gac ctg ctc cta ... ... ggt tca gaa gcg aac ctc acg tgc aca ctg acc ggc ctg aga

  X53389   IGHA*01 F   CH2 gDNA           

  AB013758 IGHA*02 F   CH2 gDNA           

  AB013764 IGHA*03 F   CH2 gDNA           


                                     _______BC___________________                            _____________CD_________
                                                                                             45.1    45.3    45.5    
                                      30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                      N   P       S   G   A   T   F   T   W   T   P   S   S   G   K   N             
  X53705   IGHA*01 F   CH2 gDNA      aat ccc ... tcg ggt gcc acc ttc acc tgg acg ccc tca agt ggg aag aac ... ... ...

  X53389   IGHA*01 F   CH2 gDNA          

  AB013758 IGHA*02 F   CH2 gDNA          

  AB013764 IGHA*03 F   CH2 gDNA          


                                     ____                                ___________________________DE_______________
                                     45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                          77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                          A   V   Q   Q   S   P   K   R   D   P   C   G                             
  X53705   IGHA*01 F   CH2 gDNA      ... gct gtc caa cag tca cct aag cgt gac ccc tgt ggc ... ... ... ... ... ... ...

  X53389   IGHA*01 F   CH2 gDNA          

  AB013758 IGHA*02 F   CH2 gDNA           

  AB013764 IGHA*03 F   CH2 gDNA          


                                     ____________                                                ___EF___            
                                         85.2                                                    96.1                
                                     85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                      C   Y   S   V   S   S   V   L   P   G   C   A   E   P   W           N   N   R 
  X53705   IGHA*01 F   CH2 gDNA      tgc tac agt gtg tcc agt gtc ctg ccc ggc tgt gcc gag cca tgg ... ... aac aat agg

  X53389   IGHA*01 F   CH2 gDNA           

  AB013758 IGHA*02 F   CH2 gDNA           

  AB013764 IGHA*03 F   CH2 gDNA           


                                                         _________________________FG_________________________        
                                      
                                     100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                      V   T   F   T   C   T   A   E   H   P   E           L   E   T   Q   L   T   A 
  X53705   IGHA*01 F   CH2 gDNA      gtg acc ttc acc tgc act gct gag cac cct gag ... ... ttg gag acc caa cta act gcc

  X53389   IGHA*01 F   CH2 gDNA          

  AB013758 IGHA*02 F   CH2 gDNA          

  AB013764 IGHA*03 F   CH2 gDNA          


                                                         
                                      
                                     120 121 122 123 124 
                                      T   I   S   K   P  
  X53705   IGHA*01 F   CH2 gDNA      acc atc tca aaa ccc 

  X53389   IGHA*01 F   CH2 gDNA           

  AB013758 IGHA*02 F   CH2 gDNA           

  AB013764 IGHA*03 F   CH2 gDNA           


                                                                                                                     
                                        
                                      1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                       G   N   T   F   R   P   E   V   H   L   L   P   P   P   S   E 
  X53705   IGHA*01 F   CH3-CHS gDNA                   gga aac aca ttc cgg ccc gag gtc cac ctg ctg ccg ccg ccg tcg gag


                                                  _____AB_____                                            ____________
                                                  15.1    15.3                                                        
                                       13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                       E   L   A   L           N   E   L   V   T   L   T   C   L   A   R   G   F   S 
  X53705   IGHA*01 F   CH3-CHS gDNA   gag ctg gcc ctg ... ... aac gag ctg gtg acg ctg acg tgc ctg gca cgc ggc ttc agc


                                      _______BC___________________                            _____________CD_________
                                                                                              45.1    45.3    45.5    
                                       30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                       P           E   D   V   L   V   R   W   L   K   G   T   E   Q   L   P   R   D 
  X53705   IGHA*01 F   CH3-CHS gDNA   ccc ... ... gag gat gtg ctg gtt cgc tgg ctg aag gga aca gaa cag ctg ccc cgt gac


                                      ____                                ___________________________DE_______________
                                      45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                           77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                           K   Y   L   T   W   E   S   R   K   E   P   S   Q   G               T   T 
  X53705   IGHA*01 F   CH3-CHS gDNA   ... aag tac ctg act tgg gaa tcc cgg aag gag ccc agc cag ggc ... ... ... acc acc


                                      ____________                                                ___EF___            
                                          85.2                                                    96.1                
                                      85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                       T   F   A   V   T   S   I   L   R   V   A   A   E   D   W           K   K   G 
  X53705   IGHA*01 F   CH3-CHS gDNA   acc ttc gcc gtg acc agc ata ctg cgc gtg gca gcc gag gac tgg ... ... aag aag ggg


                                                          _________________________FG_________________________        
                                        
                                      100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                       D   T   F   S   C   M   V   G   H   E   A       L   P   L   A   F   T   Q   K 
  X53705   IGHA*01 F   CH3-CHS gDNA   gac acc ttc tcc tgc atg gtg ggc cac gag gcc ... ctg ccg ctg gcc ttc aca cag aag


                                                                          ______________________________________CHS___
                                        
                                      120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 
                                       T   I   D   R   L   A               G   K   P   T   H   V   N   V   S   V   V 
  X53705   IGHA*01 F   CH3-CHS gDNA   acc atc gac cgc ctg gcg ... ... ... ggt aaa ccc acc cac gtc aat gtg tct gtg gtc


                                      ____________________________________
                                        
                                      140 141 142 143 144 145 146 147 148 
                                       M   A   E   V   D   G   T   C   Y  
  X53705   IGHA*01 F   CH3-CHS gDNA   atg gcg gaa gtg gac ggc acc tgc tac 

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
30/01/2014
Last updated:
03/02/2017
Authors:
Perrine Pégorier, Saida Saljoqi