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When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

	
	
	                                                                                                                       
                                       
                                       1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                        G   S   A   S   A   P   T   L   F   P   L   V   S   C   E   N 
  Macfas_2_Chr7 IGHM*01 F CH1 gDNA                     ggg agt gca tcc gcc cca acc ctt ttc ccc ctc gtc tcc tgt gag aat


                                                   _____AB_____                                            ____________
                                                   15.1    15.3                                                        
                                        13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                        A   P   L   D           T   N   E   V   A   V   G   C   L   A   Q   D   F   L 
  Macfas_2_Chr7 IGHM*01 F CH1 gDNA     gcc ccg ttg gat ... ... aca aac gaa gtg gcc gtt ggc tgc ctc gca cag gac ttc ctt


                                       _______BC___________________                            _____________CD_________
                                                                                               45.1    45.3    45.5    
                                        30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                        P           D   S   I   T   F   S   W   K   F   K   N   N   S   D   I   S   K 
  Macfas_2_Chr7 IGHM*01 F CH1 gDNA     ccc ... ... gac tcc atc act ttc tcc tgg aaa ttc aag aac aac tct gac atc agc aaa


                                       ____                                ___________________________DE_______________
                                       45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                            77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                            G   V   W   G   F   P   S   V   L   R   G   G                             
  Macfas_2_Chr7 IGHM*01 F CH1 gDNA     ... ggc gtc tgg ggc ttc cca tca gtc ctg aga ggg ggc ... ... ... ... ... ... ...


                                       ____________                                                ___EF___            
                                           85.2                                                    96.1                
                                       85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                        K   Y   A   A   T   S   Q   V   L   L   A   S   K   D   V   M   Q   G   T   D 
  Macfas_2_Chr7 IGHM*01 F CH1 gDNA     aag tac gcg gcc acc tcg cag gtg ctg ctg gct tcc aag gac gtc atg cag ggc aca gac


                                                           _________________________FG_________________________        
                                       
                                       100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                        E   H   V   V   C   K   V   Q   H   P                   N   G   N   K   E   Q 
  Macfas_2_Chr7 IGHM*01 F CH1 gDNA     gaa cac gtg gta tgc aaa gtc cag cac ccc ... ... ... ... aat ggc aac aaa gaa cag


                                                           
                                       
                                       120 121 122 123 124 
                                        N   V   P   L   P  
  Macfas_2_Chr7 IGHM*01 F CH1 gDNA     aac gtg cct ctt cca 



                                                                                                                       
                                       
                                       1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                    V   F   A   E   R   P   P   N   V   S   V   F   V   P   P   R   D 
  Macfas_2_Chr7 IGHM*01 F CH2 gDNA                 gtg ttt gcc gag cgg cct ccc aac gtg agt gtc ttc gtc cca ccc cga gac


                                                   _____AB_____                                            ____________
                                                   15.1    15.3                                                        
                                        13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                        G   F   V   G   N       P   R   E   S   K   L   I   C   Q   A   T   G   F   S 
  Macfas_2_Chr7 IGHM*01 F CH2 gDNA     ggc ttc gtc ggc aac ... ccc cgc gag tcc aag ctc atc tgc cag gcc aca ggt ttc agc


                                       _______BC___________________                            _____________CD_________
                                                                                               45.1    45.3    45.5    
                                        30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                        P           R   Q   I   E   V   S   W   L   R   E   G   K   Q   V   G   S     
  Macfas_2_Chr7 IGHM*01 F CH2 gDNA     ccc ... ... cgg cag att gag gtg tcc tgg ctg cgc gag ggg aag cag gtg ggg tct ...


                                       ____                                ___________________________DE_______________
                                       45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                            77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                            G   I   T   T   D   R   V   E   A   E   A   K   E   S           G   P   T 
  Macfas_2_Chr7 IGHM*01 F CH2 gDNA     ... ggc atc acc acg gac cgg gtg gag gct gaa gcc aaa gag tct ... ... ggg ccc aca


                                       ____________                                                ___EF___            
                                           85.2                                                    96.1                
                                       85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                        T   F   K   V   T   S   T   L   T   V   S   E   T   D   W           L   S   Q 
  Macfas_2_Chr7 IGHM*01 F CH2 gDNA     acc ttc aag gtg acc agc aca ctg acc gtc agc gag aca gac tgg ... ... ctc agc cag


                                                           _________________________FG_________________________        
                                       
                                       100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                        S   V   F   T   C   R   V   D   H   R                   G   L   T   F   Q   K 
  Macfas_2_Chr7 IGHM*01 F CH2 gDNA     agc gtg ttc acc tgc cgc gtg gat cac agg ... ... ... ... ggc ctg acc ttc cag aag


                                                                       
                                       
                                       120 121 122 123 124 125 126 127 
                                        N   V   S   S   V   C   C   P  
  Macfas_2_Chr7 IGHM*01 F CH2 gDNA     aac gtg tcc tcc gtg tgt tgc ccc 



                                                                                                                       
                                       
                                       1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                        N   P   D   T   A   I   R   V   F   A   I   P   P   S   F   A 
  Macfas_2_Chr7 IGHM*01 F CH3 gDNA                     aat cca gac aca gcc atc cgg gtc ttc gcc atc ccc cca tcc ttt gcc


                                                   _____AB_____                                            ____________
                                                   15.1    15.3                                                        
                                        13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                        S   I   F   L           T   K   S   T   K   L   T   C   L   V   T   D   L   A 
  Macfas_2_Chr7 IGHM*01 F CH3 gDNA     agc atc ttc ctc ... ... acc aag tcc acc aag ttg acc tgc ctg gtc aca gac ctg gcc


                                       _______BC___________________                            _____________CD_________
                                                                                               45.1    45.3    45.5    
                                        30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                        T   Y       D   S   V   T   I   T   W   T   R   Q   N   G   E   A   L         
  Macfas_2_Chr7 IGHM*01 F CH3 gDNA     acc tac ... gac agt gtg acc atc acc tgg acc cgc cag aat ggc gaa gct ctg ... ...


                                       ____                                ___________________________DE_______________
                                       45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                            77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                            K   T   H   T   N   I   S   E   S   H   P   N                           G 
  Macfas_2_Chr7 IGHM*01 F CH3 gDNA     ... aaa acc cac acc aac atc tcc gag agc cac ccc aat ... ... ... ... ... ... ggc


                                       ____________                                                ___EF___            
                                           85.2                                                    96.1                
                                       85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                        T   F   S   A   V   G   E   A   S   I   C   E   D   D   W           N   S   G 
  Macfas_2_Chr7 IGHM*01 F CH3 gDNA     acc ttc agc gct gtg ggt gag gcc agc atc tgc gag gac gac tgg ... ... aac tcc ggg


                                                           _________________________FG_________________________        
                                       
                                       100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                        E   R   F   R   C   T   V   T   H   T   D           L   P   S   P   L   K   Q 
  Macfas_2_Chr7 IGHM*01 F CH3 gDNA     gag agg ttc agg tgc acc gtg acc cac acg gac ... ... ctg ccc tcg ccg ctg aag cag


                                                               
                                       
                                       120 121 122 123 124 125 
                                        T   I   S   R   P   K  
  Macfas_2_Chr7 IGHM*01 F CH3 gDNA     acc atc tcc agg ccc aag 



                                                                                                                           
                                           
                                           1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                        G   V   A   M   H   R   P   D   V   Y   L   L   P   P   A   R   E 
  Macfas_2_Chr7 IGHM*01 F CH4-CHS gDNA                 ggg gtg gcc atg cac agg ccc gat gtc tac ttg ctg cca cca gcc cgg gaa


                                                       _____AB_____                                            ____________
                                                       15.1    15.3                                                        
                                            13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                            Q   L   N   L           R   E   S   A   T   I   T   C   L   V   T   G   F   S 
  Macfas_2_Chr7 IGHM*01 F CH4-CHS gDNA     cag ctg aac ctg ... ... cgg gag tcg gcc acc atc acc tgc ctg gtg acg ggc ttc tct


                                           _______BC___________________                            _____________CD_________
                                                                                                   45.1    45.3    45.5    
                                            30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                            P           A   D   I   F   V   Q   W   M   Q   R   G   Q   P   L   S   P   E 
  Macfas_2_Chr7 IGHM*01 F CH4-CHS gDNA     ccc ... ... gcg gac atc ttc gtg cag tgg atg cag agg ggg cag cct ttg tcc ccg gag


                                           ____                                ___________________________DE_______________
                                           45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                                77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                                K   Y   V   T   S   A   P   M   P   E   P   Q   A                   P   G 
  Macfas_2_Chr7 IGHM*01 F CH4-CHS gDNA     ... aag tat gtg acc agt gcc cca atg cct gag ccc cag gcc ... ... ... ... cca ggc


                                           ____________                                                ___EF___            
                                               85.2                                                    96.1                
                                           85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                            R   Y   F   A   H   S   I   L   T   V   S   E   E   D   W           N   T   G 
  Macfas_2_Chr7 IGHM*01 F CH4-CHS gDNA     cgg tac ttc gcc cac agc atc ctg acc gtg tct gaa gag gac tgg ... ... aac acg ggg


                                                               _________________________FG_________________________        
                                           
                                           100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                            E   T   Y   T   C   V   V   A   H   E   A       L   P   N   R   V   T   E   R 
  Macfas_2_Chr7 IGHM*01 F CH4-CHS gDNA     gag acc tac acc tgc gtc gtg gcc cat gag gcc ... ctg ccc aac agg gtc acc gag agg



                                                                               ______________________________________CHS___
                                           
                                           120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 
                                            T   V   D   K   S   T               G   K   P   T   L   Y   N   V   S   L   V 
  Macfas_2_Chr7 IGHM*01 F CH4-CHS gDNA     acc gtg gac aag tcc acc ... ... ... ggt aaa ccc acc ctg tac aac gtg tcc ctc gtc



                                           ____________________________________
                                           
                                           140 141 142 143 144 145 146 147 148 
                                            M   S   D   T   A   G   T   C   Y  
  Macfas_2_Chr7 IGHM*01 F CH4-CHS gDNA     atg tcc gac aca gct ggc acc tgc tac 

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
17/01/2017
Last updated:
25/10/2017
Authors:
Perrine Pégorier