IMGT Repertoire (IG and TR)

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Dots indicate gaps according to the IMGT unique numbering.
Blanks at the 5' and/or 3' end indicate partial sequences.
Asterisk (*) in the sequence indicate a STOP-CODON.
Letters in red correspond to amino acids which are polymorphic in the other alleles.
Colours are according to Color menu for mutations, Color menu for sequence alignments and Color menu for splicing types.
The nucleotide (s) in bold and colored in purple (splicing frame 1) or green (splicing frame 2) from the DONOR splice site are added at the beginning of the following exon in order to obtain and to complete the first CODON of the DOMAIN or REGION resulting from the splicing site. These first CODONs are in bold and colored in purple (splicing frame 1) or green (splicing frame 2)
N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown in green

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 Q V Q Q V Q S G A E V K Q P G S S V K BK008924 IGHV1S4*01 P V-REGION gDNA cag gtg cag cag gtg cag tct ggg gct ... gag gtg aag cag cct ggg tcc tca gtg aag ___________________CDR1-IMGT____________________ 21 22 23 24 25 26 26A 27 28 29 30 31 32 33 34 35 36 37 38 39 V S C K A S G Y T F T S S V M BK008924 IGHV1S4*01 P V-REGION gDNA gtc tcc tgc aag gct tct ... gga tac acc ttt ... ... ... ... act agc tct gtt atg _______________C 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 Q W V R Q A P G Q G L Q * I G R I C P Y BK008924 IGHV1S4*01 P V-REGION gDNA cag tgg gtg cga cag gcc cct gga caa ggc ctt cag tag ata gga cgg atc tgc cct tac DR2-IMGT________________ 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 N G N T K Y A Q N F Q G R V T M T BK008924 IGHV1S4*01 P V-REGION gDNA ... ... aat ggt aac acg aag tat gca cag aac ttc cag ... ggc aga gtc acc atg acc 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 T D T S T S T A C M E L S S L R S E D T BK008924 IGHV1S4*01 P V-REGION gDNA acg gac acg tcc acg agc aca gcc tgc atg gag ctg agc agc ctg aga tct gag gac aca ___CDR3-IMGT____ 100 101 102 103 104 105 106 107 A V Y Y C A R D BK008924 IGHV1S4*01 P V-REGION gDNA gcc gtg tat tac tgt gcg aga gac a

Legend:

*: STOP_CODON mutation

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:: 15/12/2016
Last updated:: 27/01/2017
Authors:: Perrine Pégorier

IMGT Repertoire (IG and TR)

Alignment of alleles: crab-eating macaque (Macaca fascicularis) IGHV1S4