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When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

	
	
	                                                                                                                          
                                          
                                           1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                           Q   V   Q   L   V   Q   S   G   A       D   G   K   K   P   G   S   S   V   K 
  BK008952 IGHV1S8*01 P V-REGION gDNA     cag gtc cag ctg gtg cag tct ggg gct ... gac ggg aag aag cct ggg tcc tca gtg aag


                                                                      ___________________CDR1-IMGT____________________    
                                          
                                           21  22  23  24  25  26 26A  27  28  29  30  31  32  33  34  35  36  37  38  39 
                                           V   S   C   K   A   S       G   Y   I   F                   T   S   S   A   M 
  BK008952 IGHV1S8*01 P V-REGION gDNA     gtc tcc tgc aag gct tct ... gga tac atc ttt ... ... ... ... act agc tct gct atg


                                                                                                          _______________C
                                          
                                           40  41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59 
                                           *   W   V   R   Q   A   P   G   Q   G   L   E   W   I   G   V   I   I   I   G 
  BK008952 IGHV1S8*01 P V-REGION gDNA     tag tgg gtg cga cag gcc cct gga caa ggc ctt gag tgg ata gga gtg atc atc att ggc


                                          DR2-IMGT________________                                                        
                                          
                                           60  61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79 
                                                   N   G   N   T   G   Y   A   Q   M   F   Q       G   R   V   T   I   T 
  BK008952 IGHV1S8*01 P V-REGION gDNA     ... ... aat ggt aac aca ggc tat gca cag atg ttc cag ... ggc aga gtc acc att acc


                                                                                                                          
                                          
                                           80  81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 
                                           R   D   T   S   M   S   T   A   Y   V   E   L   S   S   L   R   S   E   D   T 
  BK008952 IGHV1S8*01 P V-REGION gDNA     agg gac acg tcc atg agc aca gcc tac gtg gag ctg agc agc ctg aga tcc gag gac acg


                                                              _CDR3-IMGT__
                                          
                                          100 101 102 103 104 105 106 
                                           A   V   Y   Y   C   A   A  
  BK008952 IGHV1S8*01 P V-REGION gDNA     gcc gtg tat tac tgt gcg gca ga


Legend:

*: STOP_CODON mutation

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
15/12/2016
Last updated:
27/01/2017
Authors:
Perrine Pégorier