IMGT Repertoire (IG and TR)

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Dots indicate gaps according to the IMGT unique numbering.
Blanks at the 5' and/or 3' end indicate partial sequences.
Asterisk (*) in the sequence indicate a STOP-CODON.
Letters in red correspond to amino acids which are polymorphic in the other alleles.
Colours are according to Color menu for mutations, Color menu for sequence alignments and Color menu for splicing types.
The nucleotide (s) in bold and colored in purple (splicing frame 1) or green (splicing frame 2) from the DONOR splice site are added at the beginning of the following exon in order to obtain and to complete the first CODON of the DOMAIN or REGION resulting from the splicing site. These first CODONs are in bold and colored in purple (splicing frame 1) or green (splicing frame 2)
N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown in green

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

                                                                                                                                   
                                           
                                            1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                            Q   V   Q   L   Q   E   S   G   P       G   L   V   K   P   S   E   T   L   S 
  BK008971 IGHV4S19*01 F V-REGION gDNA     cag gtg cag ctg cag gag tcg ggc cca ... gga ctg gtg aag cct tca gag acc ctg tcc


                                                                       ___________________CDR1-IMGT____________________    
                                           
                                            21  22  23  24  25  26 26A  27  28  29  30  31  32  33  34  35  36  37  38  39 
                                            L   T   C   A   V   S       G   G   S   I               S   S   S   N   W   W 
  BK008971 IGHV4S19*01 F V-REGION gDNA     ctc acc tgc gct gtc tct ... ggt ggc tct atc ... ... ... agc agt agt aac tgg tgg


                                                                                                           _______________C
                                           
                                            40  41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59 
                                            S   W   I   R   Q   P   P   G   K   G   L   E   W   I   G   N   I   G   G   S 
  BK008971 IGHV4S19*01 F V-REGION gDNA     agc tgg atc cgc cag ccc cca ggg aaa ggg ctg gag tgg att ggg aat atc ggt ggt agt


                                           DR2-IMGT________________                                                        
                                           
                                            60  61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79 
                                                    S   G   S   T   Y   Y   N   P   S   L   K       S   R   V   T   I   S 
  BK008971 IGHV4S19*01 F V-REGION gDNA     ... ... agt ggt agc acc tac tac aac ccc tcc ctc aag ... agt cga gtc acc att tca


                                                                                                                           
                                           
                                            80  81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 
                                            K   D   T   S   K   N   Q   F   S   L   K   L   S   S   V   T   A   A   D   T 
  BK008971 IGHV4S19*01 F V-REGION gDNA     aaa gac acg tcc aag aac cag ttc tcc ctg aag ctg agc tct gtg acc gcc gcg gac acg


                                                               _CDR3-IMGT__
                                           
                                           100 101 102 103 104 105 106 
                                            A   V   Y   Y   C   A   R  
  BK008971 IGHV4S19*01 F V-REGION gDNA     gcc gtg tat tac tgt gcg aga ga

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:: 15/12/2016
Last updated:: 17/01/2017
Authors:: Perrine Pégorier

IMGT Repertoire (IG and TR)

Alignment of alleles: crab-eating macaque (Macaca fascicularis) IGHV4S19