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When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

	
	
	                                                                                                                            
                                            
                                             1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                             Q   V   Q   L   Q   E   L   G   P       G   L   E   K   P   S   Q   T   V   S 
  BK009034 IGHV4S2*01 ORF V-REGION gDNA     cag gtg cag ttg cag gag ttg ggt cct ... gga ctg gag aag ccc tct cag acc gtc tcc
                                                                                                                           
  BK009003 IGHV4S2*01 ORF V-REGION gDNA                                                                                    


                                                                        ___________________CDR1-IMGT____________________    
                                            
                                             21  22  23  24  25  26 26A  27  28  29  30  31  32  33  34  35  36  37  38  39 
                                             L   P   C   T   V   S       G   F   S   I   T           T   S   S   T   Y   W 
  BK009034 IGHV4S2*01 ORF V-REGION gDNA     ctc ccc tgc act gtc tct ... ggt ttc tcc ata aca ... ... acc agt agt acc tac tgg
                                                                                                                           
  BK009003 IGHV4S2*01 ORF V-REGION gDNA                                                                                    


                                                                                                            _______________C
                                            
                                             40  41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59 
                                             H   W   I   Q   K   P   L   G   K   G   L   Q   W   L   G   E   I   G   Y   S 
  BK009034 IGHV4S2*01 ORF V-REGION gDNA     cat tgg att caa aag cca ctg gga aaa ggg ctt cag tgg ctg gga gaa ata ggt tat tct
                                                                                                                           
  BK009003 IGHV4S2*01 ORF V-REGION gDNA                         --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                            DR2-IMGT________________                                                        
                                            
                                             60  61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79 
                                                         R   V   T   K   Y   N   P   S   F   W       S   H   S   S   I   S 
  BK009034 IGHV4S2*01 ORF V-REGION gDNA     ... ... ... aga gtc acc aaa tac aac cca tcc ttc tgg ... agc cac agc agc atc tcc
                                                                                                                           
  BK009003 IGHV4S2*01 ORF V-REGION gDNA     ... ... ... --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- ---


                                                                                                                            
                                            
                                             80  81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 
                                             C   D   T   L   K   K   P   L   F   L   Q   L   S   S   V   T   S   E   D   T 
  BK009034 IGHV4S2*01 ORF V-REGION gDNA     tgt gac aca ttg aaa aaa ccg tta ttc ctc cag ctg agc tct gtg acc tcg gag gac aca
                                                                                                                           
  BK009003 IGHV4S2*01 ORF V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                                _CDR3-IMGT__
                                            
                                            100 101 102 103 104 105 106 
                                             A   L   C   Y   C   V   R  
  BK009034 IGHV4S2*01 ORF V-REGION gDNA     gct ctg tgt tac tgt gtg aga gg
                                                                        
  BK009003 IGHV4S2*01 ORF V-REGION gDNA     --- --- --- --- --- --- --- --

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
15/12/2016
Last updated:
17/01/2017
Authors:
Perrine Pégorier