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When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

	
	
	                                                                                                                             
                                             
                                              1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                              D   I   V   M   I   Q   T   P   L   S   L   P   V   T   L   G   E   P   A   S 
  AY963757 IGKV2S18*01   F   V-REGION gDNA   gat att gtg atg atc cag act cca ctc tcc ctg ccc gtc acc ctt gga gag ccg gcc tcc
                                                                                                                            
  AY963758 IGKV2S18*01   F   V-REGION gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                            
  AY963761 IGKV2S18*01   F   V-REGION gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                                     ___________________CDR1-IMGT____________________        
                                             
                                              21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40 
                                              I   S   C   R   S   S   Q   S   L   V   Y   S       D   G   K   T   Y   L   Y 
  AY963757 IGKV2S18*01   F   V-REGION gDNA   atc tcc tgc agg tcc agt cag agc ctt gta tac agt ... gat gga aaa acc tat ttg tat
                                                                                                                            
  AY963758 IGKV2S18*01   F   V-REGION gDNA   --- --- --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---
                                                                                                                            
  AY963761 IGKV2S18*01   F   V-REGION gDNA   --- --- --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---


                                                                                                         _______________CDR2-
                                             
                                              41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60 
                                              W   Y   L   Q   K   P   G   Q   S   P   Q   L   L   M   Y   L   V             
  AY963757 IGKV2S18*01   F   V-REGION gDNA   tgg tac ctg cag aag cca ggc cag tct cca cag ctc ctg atg tat ttg gtt ... ... ...
                                                                                                                            
  AY963758 IGKV2S18*01   F   V-REGION gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ...
                                                                                                                            
  AY963761 IGKV2S18*01   F   V-REGION gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ...


                                             IMGT________________                                                            
                                             
                                              61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79  80 
                                                              S   K   R   A   S   G   V   P       D   K   F   S   G   S   G 
  AY963757 IGKV2S18*01   F   V-REGION gDNA   ... ... ... ... tcc aaa cgg gcc tct gga gtc cca ... gac aag ttc agt ggc agt ggg
                                                                                                                            
  AY963758 IGKV2S18*01   F   V-REGION gDNA   ... ... ... ... --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---
                                                                                                                            
  AY963761 IGKV2S18*01   F   V-REGION gDNA   ... ... ... ... --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---


                                                                                                                             
                                             
                                              81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 100 
                                                      S   G   T   D   F   T   L   K   I   S   R   V   E   A   E   D   V   G 
  AY963757 IGKV2S18*01   F   V-REGION gDNA   ... ... tca ggc act gat ttc aca ctg aaa atc agc agg gtg gag gct gag gat gtt ggg
                                                                                                                            
  AY963758 IGKV2S18*01   F   V-REGION gDNA   ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                                                                            
  AY963761 IGKV2S18*01   F   V-REGION gDNA   ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                             ___________CDR3-IMGT____________
                                             
                                             101 102 103 104 105 106 107 108 109 110 111 
                                              V   Y   Y   C   M   Q   A   L   R   S   P  
  AY963757 IGKV2S18*01   F   V-REGION gDNA   gtt tat tac tgc atg caa gct cta cgg tct cct tc
                                                                                         
  AY963758 IGKV2S18*01   F   V-REGION gDNA   --- --- --- --- --- --- --- --- --- --- --- --
                                                                                         
  AY963761 IGKV2S18*01   F   V-REGION gDNA   --- --- --- --- --- --- --- --- --- --- --- --

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
23/09/2014
Last updated:
27/05/2016
Authors:
Géraldine Folch