Here you are: IMGT Web resources > IMGT Repertoire > Proteins and alleles

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

	
	
	                                                                                
                                        
                                        1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                         V   G   Q   R   A   P   E   V   Y   P   L   Y   A   G   C   G 
  NW_001794226 IGHD*01   F   CH1 gDNA                   gta gga caa cgg gct cca gaa gtg tac cca ctg tat gca ggg tgt gga
                                                                                                                       
  EU503149     IGHD*02   F   CH1 cDNA                   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                    _____AB_____                                            ____________
                                                    15.1    15.3                                                        
                                         13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                         S   P   A   P   A       E   D   K   V   T   L   V   C   L   A   T   N   F   S 
  NW_001794226 IGHD*01   F   CH1 gDNA   agc cct gcc cct gca ... gag gac aag gtg acc ttg gtc tgc ttg gca acc aac ttt tcc
                                                                                                                       
  EU503149     IGHD*02   F   CH1 cDNA   --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                        _______BC___________________                            _____________CD_________
                                                                                                45.1    45.3    45.5    
                                         30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                         P                   N   D   L   A   F   T   W   N   I   K   D   D   V   K     
  NW_001794226 IGHD*01   F   CH1 gDNA   cca ... ... ... ... aat gat ttg gct ttc acc tgg aac atc aaa gat gat gtg aag ...
                                                                                                                       
  EU503149     IGHD*02   F   CH1 cDNA   --- ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ...


                                        ____                                ___________________________DE_______________
                                        45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                             77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                                     N   F   P   S   V   R   R   S   D   M   T                         
  NW_001794226 IGHD*01   F   CH1 gDNA   ... ... ... aac ttt cca tcc gtc cga agg tct gac atg aca ... ... ... ... ... ...
                                                                                                                       
  EU503149     IGHD*02   F   CH1 cDNA   ... ... ... --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ...


                                        ____________                                                ___EF___            
                                            85.2                                                    96.1                
                                        85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                                     Y   I   E   S   S   Q   L   T   F   P   A   S   K   W             
  NW_001794226 IGHD*01   F   CH1 gDNA   ... ... ... tac ata gag agc agc caa ctc acc ttc cca gcc tca aag tgg ... ... ...
                                                                                                                       
  EU503149     IGHD*02   F   CH1 cDNA   ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ...


                                                            _________________________FG_________________________        
                                        
                                        100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                         D   S   E   T   P   T   C   T   V   K   H   N               Q   Q   K   E   K 
  NW_001794226 IGHD*01   F   CH1 gDNA   gac tct gag aca ccc act tgc acg gtg aaa cac aat ... ... ... cag caa aaa gaa aag
                                                                                                                       
  EU503149     IGHD*02   F   CH1 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... --- --- --- --- ---


                                                                        
                                        
                                        120 121 122 123 124 125 126 127 
                                         K   I   I   V   F   K   R   Q  
  NW_001794226 IGHD*01   F   CH1 gDNA   aaa atc att gtg ttt aaa cgc caa 
                                                                        
  EU503149     IGHD*02   F   CH1 cDNA   --- --- --- --- --- --- --- --- 




                                                                                                                        
                                        
                                        1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                     D   Q   R   M   Q   P   P   R   V   H   L   L   P   P   P   C   V 
  NW_001794226 IGHD*01   F   CH2 gDNA               gac caa agg atg cag cca ccc aga gtg cat ctc ttg ccc cca ccc tgc gtt
                                                                                                                 Y     
  EU503149     IGHD*02   F   CH2 cDNA               --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -a- ---


                                                    _____AB_____                                            ____________
                                                    15.1    15.3                                                        
                                         13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                         G   T   S   E           G   G   T   V   E   L   I   C   L   L   L   Q   F   K 
  NW_001794226 IGHD*01   F   CH2 gDNA   ggc acc tca gag ... ... ggt ggc act gtg gaa ctc atc tgc ctg ctg ctt cag ttc aag
                                                                                                                       
  EU503149     IGHD*02   F   CH2 cDNA   --- --- --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                        _______BC___________________                            _____________CD_________
                                                                                                45.1    45.3    45.5    
                                         30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                         P                   N   S   T   E   V   Q   W   L   L   N   G   R   E   L   N 
  NW_001794226 IGHD*01   F   CH2 gDNA   ccc ... ... ... ... aac tcc aca gag gtg cag tgg ctt ttg aat ggg cgg gag ttg aac
                                                                                                                       
  EU503149     IGHD*02   F   CH2 cDNA   --- ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                        ____                                ___________________________DE_______________
                                        45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                             77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                         K           P   A   P   T   L   F   A   A   D   Q   D   G                     
  NW_001794226 IGHD*01   F   CH2 gDNA   aaa ... ... ccc gcg ccc acc ctc ttt gcc gcc gac cag gat ggc ... ... ... ... ...
                                                                                                                       
  EU503149     IGHD*02   F   CH2 cDNA   --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ...


                                        ____________                                                ___EF___            
                                            85.2                                                    96.1                
                                        85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                                 S   F   M   A   R   S   L   L   R   I   S   S   S   N   W           E 
  NW_001794226 IGHD*01   F   CH2 gDNA   ... ... tct ttc atg gcc cgc agc ctc ctg aga atc tcc agt tcg aac tgg ... ... gag
                                                                                                                       
  EU503149     IGHD*02   F   CH2 cDNA   ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ---


                                                            _________________________FG_________________________        
                                        
                                        100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                         G   G   D   T   F   T   C   R   V   T   H   P   A           L   K   E   G   P 
  NW_001794226 IGHD*01   F   CH2 gDNA   ggc ggg gac acg ttc acc tgt agg gtc acg cac cct gcc ... ... ctg aag gag ggc ccg
                                                                                                                       
  EU503149     IGHD*02   F   CH2 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- ---


                                                                            
                                        
                                        120 121 122 123 124 125 126 127 128 
                                         E   L   Y   N   S   S   K   C   S  
  NW_001794226 IGHD*01   F   CH2 gDNA   gag ctc tac aac agc agc aag tgc tca 
                                                                            
  EU503149     IGHD*02   F   CH2 cDNA   --- --- --- --- --- --- --- --- --- 




                                                                                                                        
                                        
                                        1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                             A   C   H   S   H   A   T   A   M   T   L   Y   L   F   A   P   S   Y   D 
  NW_001794226 IGHD*01   F   CH3 gDNA       gcc tgt cac agc cat gcc act gcg atg acc cta tac ctc ttc gca ccc tcc tac gat
                                                                                                                       
  EU503149     IGHD*02   F   CH3 cDNA       --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                    _____AB_____                                            ____________
                                                    15.1    15.3                                                        
                                         13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                         E   L   V   R   G       N   G   K   G   H   A   T   C   L   V   L   G   Y   D 
  NW_001794226 IGHD*01   F   CH3 gDNA   gag ctg gtc agg ggg ... aat ggg aag ggc cac gcg acc tgc ctc gtg ctg ggc tac gac
                                                                                                                       
  EU503149     IGHD*02   F   CH3 cDNA   --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                        _______BC___________________                            _____________CD_________
                                                                                                45.1    45.3    45.5    
                                         30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                         L                   A   S   V   Q   I   S   W   Q   V   N   G   V   V   T   E 
  NW_001794226 IGHD*01   F   CH3 gDNA   tta ... ... ... ... gcc agt gtc cag atc agc tgg caa gtg aat gga gtt gtc act gag
                                                                                                                       
  EU503149     IGHD*02   F   CH3 cDNA   --- ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                        ____                                ___________________________DE_______________
                                        45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                             77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                         G   Q       T   G   V   T   R   H   E   S   N   G   T   E   S                 
  NW_001794226 IGHD*01   F   CH3 gDNA   ggc cag ... acg ggg gtc acg agg cat gaa agc aat gga acg gag agc ... ... ... ...
                                                                                                                       
  EU503149     IGHD*02   F   CH3 cDNA   --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ...


                                        ____________                                                ___EF___            
                                            85.2                                                    96.1                
                                        85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                             R   T   S   T   Q   T   I   S   L   A   D   W   K   A                     
  NW_001794226 IGHD*01   F   CH3 gDNA   ... agg aca agc acc cag acc atc tca ctg gct gat tgg aaa gct ... ... ... ... ...
                                                                                                                       
  EU503149     IGHD*02   F   CH3 cDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ...


                                                            _________________________FG_________________________        
                                        
                                        100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                             G   R   R   Y   I   C   R   A   K   H   P   C   V   K   E   V   T   Q   E 
  NW_001794226 IGHD*01   F   CH3 gDNA   ... ggc agg agg tac atc tgc aga gcc aag cat cct tgc gtg aag gaa gtc act cag gag
                                                                                                                       
  EU503149     IGHD*02   F   CH3 cDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                                
                                        
                                        120 121 122 123 124 125 
                                         L   S   T   F   D   P  
  NW_001794226 IGHD*01   F   CH3 gDNA   ctg tcc acg ttc gac ccc 
                                                                
  EU503149     IGHD*02   F   CH3 cDNA   --- --- --- --- --- --- 




                                                                                                                        
                                        
                                        1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                 K   T   P   T   K   K   P   S   V   S   V   S   R   V   F   S   E   D 
  NW_001794226 IGHD*01   F   CH4 gDNA           aag acc ccc acg aag aag ccc tca gtg tcc gtc tcc cgg gtt ttc tca gaa gat
                                                                                                                       
  EU503149     IGHD*02   F   CH4 cDNA           --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                    _____AB_____                                            ____________
                                                    15.1    15.3                                                        
                                         13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                         S   P   G   E           E   D   H   P   T   L   L   C   N   I   R   G   F   Y 
  NW_001794226 IGHD*01   F   CH4 gDNA   tcc cca gga gag ... ... gaa gat cat ccg act ctg ctc tgc aac att cga ggt ttc tat
                                                                                                                       
  EU503149     IGHD*02   F   CH4 cDNA   --- --- --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                        _______BC___________________                            _____________CD_________
                                                                                                45.1    45.3    45.5    
                                         30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                         P                   K   E   L   S   V   S   W   E   N   N   S   H   P   L   P 
  NW_001794226 IGHD*01   F   CH4 gDNA   ccc ... ... ... ... aaa gag ctc agc gtc agc tgg gag aac aac agc cac cca ctc ccc
                                                                                                                       
  EU503149     IGHD*02   F   CH4 cDNA   --- ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                        ____                                ___________________________DE_______________
                                        45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                             77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                                     R   T   L   Y   S   S   G   P   V   V   A   T                     
  NW_001794226 IGHD*01   F   CH4 gDNA   ... ... ... agg acc ttg tac agc agc ggg ccc gtg gtg gcc act ... ... ... ... ...
                                                                                                                       
  EU503149     IGHD*02   F   CH4 cDNA   ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ...


                                        ____________                                                ___EF___            
                                            85.2                                                    96.1                
                                        85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                         G   N   E   A   F   S   T   Y   S   L   L   R   V   G   P   G   E             
  NW_001794226 IGHD*01   F   CH4 gDNA   ggc aac gag gcc ttc tcc aca tac agc ctc ctg cgt gtg ggc ccc ggg gag ... ... ...
                                                                                                                       
  EU503149     IGHD*02   F   CH4 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ...


                                                            _________________________FG_________________________        
                                        
                                        100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                         R   G   G   A   Y   T   C   V   V   M   H   P   S       T   D   R   P   T   R 
  NW_001794226 IGHD*01   F   CH4 gDNA   aga gga ggg gcc tac acc tgt gtt gtg atg cat ccg tca ... aca gac cgg ccc act cgt
                                                                                                                       
  EU503149     IGHD*02   F   CH4 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- ---


                                                                
                                        
                                        120 121 122 123 124 125 
                                         S   N   K   V   S   F  
  NW_001794226 IGHD*01   F   CH4 gDNA   tcc aac aag gtt tca ttt 
                                                                
  EU503149     IGHD*02   F   CH4 cDNA   --- --- --- --- --- --- 




                                                                                                                        
                                        
                                        1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                 D   W   A   L   S   R   A   P   E   V   S   I   T   G   H   P   A   C 
  NW_001794226 IGHD*01   F   CH5 gDNA           gac tgg gct ctc tcc agg gcc cca gag gtg tcc atc act ggc cat cct gct tgc
                                                                                                                       
  EU503149     IGHD*02   F   CH5 cDNA           --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                    _____AB_____                                            ____________
                                                    15.1    15.3                                                        
                                         13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                         N   A   P   G           A   E   T   S   V   F   R   C   S   A   S   N   F   F 
  NW_001794226 IGHD*01   F   CH5 gDNA   aat gcc ccg gga ... ... gct gag acc agt gtc ttc cgc tgc tct gcc agt aac ttc ttt
                                                                                                                       
  EU503149     IGHD*02   F   CH5 cDNA   --- --- --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                        _______BC___________________                            _____________CD_________
                                                                                                45.1    45.3    45.5    
                                         30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                         P                   A   G   A   E   I   L   W   L   V   K   G   Q   E   Q   P 
  NW_001794226 IGHD*01   F   CH5 gDNA   ccc ... ... ... ... gcg gga gct gag atc ctc tgg ctg gtg aaa ggg cag gag cag ccg
                                                                                 R                                     
  EU503149     IGHD*02   F   CH5 cDNA   --- ... ... ... ... --- --- --- --- --- -g- --- --- --- --- --- --- --- --- ---


                                        ____                                ___________________________DE_______________
                                        45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                             77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                         G           L   T   Q   T   I   T   R   S   R   D   G   R                     
  NW_001794226 IGHD*01   F   CH5 gDNA   ggg ... ... ttg acc cag acc atc acc cgg agt cgg gat ggc cgg ... ... ... ... ...
                                                                                                                       
  EU503149     IGHD*02   F   CH5 cDNA   --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ...


                                        ____________                                                ___EF___            
                                            85.2                                                    96.1                
                                        85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                                     Y   S   A   S   L   E   L   S   V   P   N   A   Q   W           N 
  NW_001794226 IGHD*01   F   CH5 gDNA   ... ... ... tac agc gcc agc ctg gag ctc tcg gtg ccc aac gcc cag tgg ... ... aac
                                                                                                                       
  EU503149     IGHD*02   F   CH5 cDNA   ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ---


                                                            _________________________FG_________________________        
                                        
                                        100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                         Q   L   A   E   F   T   C   R   V   S   H   A   G           A   T   Q   Q   K 
  NW_001794226 IGHD*01   F   CH5 gDNA   cag ctg gcc gag ttc acc tgc cgg gtc agc cac gct gga ... ... gcc acg cag caa aaa
                                                                                                                       
  EU503149     IGHD*02   F   CH5 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- ---


                                                                
                                        
                                        120 121 122 123 124 125 
                                         N   L   S   K   C   A  
  NW_001794226 IGHD*01   F   CH5 gDNA   aac ctg agc aag tgt gca 
                                                                
  EU503149     IGHD*02   F   CH5 cDNA   --- --- --- --- --- --- 




                                                                                                                        
                                        
                                        1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                             V   C   Q   D   S   T   P   Q   P   T   L   Y   L   L   P   P   P   L   E 
  NW_001794226 IGHD*01   F   CH6 gDNA       gtc tgc cag gac agc acc ccc cag ccc act ctc tac ctc ctg ccc cca ccc ctg gaa
                                                                                                                       
  EU503149     IGHD*02   F   CH6 cDNA       --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                    _____AB_____                                            ____________
                                                    15.1    15.3                                                        
                                         13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                         G   L   V   L           R   A   E   A   L   L   T   C   L   V   V   G   Y   Q 
  NW_001794226 IGHD*01   F   CH6 gDNA   ggc ttg gtg ctc ... ... cgg gcg gaa gcg ctc ctg acc tgc ctg gtg gtg ggc tac cag
                                                                                                                       
  EU503149     IGHD*02   F   CH6 cDNA   --- --- --- --- ... ... --- --- --- --a --- --- --- --- --- --- --- --- --- ---


                                        _______BC___________________                            _____________CD_________
                                                                                                45.1    45.3    45.5    
                                         30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                         L                   D   Q   A   T   L   T   W   E   V   D   K   K   P   L   A 
  NW_001794226 IGHD*01   F   CH6 gDNA   ctg ... ... ... ... gac cag gcc aca ctg acg tgg gaa gtg gat aaa aag ccc ctt gcc
                                                                                                                       
  EU503149     IGHD*02   F   CH6 cDNA   --- ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                        ____                                ___________________________DE_______________
                                        45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                             77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                         G           S   P   S   V   R   A   L   V   T   H   D   N                     
  NW_001794226 IGHD*01   F   CH6 gDNA   gga ... ... agc ccc agc gta aga gcc cta gtg acg cac gac aat ... ... ... ... ...
                                                                                                                       
  EU503149     IGHD*02   F   CH6 cDNA   --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ...


                                        ____________                                                ___EF___            
                                            85.2                                                    96.1                
                                        85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                             G   T   Q   S   L   R   S   H   L   N   L   S   R   T   D   W           E 
  NW_001794226 IGHD*01   F   CH6 gDNA   ... ggc acc caa agc ctc cgc agc cac ctg aac ctc tcc cgg acc gac tgg ... ... gaa
                                                                                                                       
  EU503149     IGHD*02   F   CH6 cDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ---


                                                            _________________________FG_________________________        
                                        
                                        100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                         A   A   H   T   V   L   C   R   V   S   H   R   C           L   F   A   P   Q 
  NW_001794226 IGHD*01   F   CH6 gDNA   gct gct cac acc gtc ctt tgc agg gta tcc cac cgc tgt ... ... ctg ttt gcc cct caa
                                                                                                                       
  EU503149     IGHD*02   F   CH6 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- ---


                                                                        
                                        
                                        120 121 122 123 124 125 126 127 
                                         E   E   T   L   Q   P   L   R  
  NW_001794226 IGHD*01   F   CH6 gDNA   gag gag acc ctc caa cca ctc aga 
                                                                        
  EU503149     IGHD*02   F   CH6 cDNA   --- --- --- --- --- --- --- --- 




                                                                                                                        
                                        
                                        1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                 G   A   D   P   P   R   K   L   S   I   H   V   L   H   P   S   L   P 
  NW_001794226 IGHD*01   F   CH7 gDNA           ggt gct gac cct ccc agg aag ctt tcc atc cat gta cta cat ccg agc cta cct
                                                                                                                       
  EU503149     IGHD*02   F   CH7 cDNA           --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                    _____AB_____                                            ____________
                                                    15.1    15.3                                                        
                                         13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                         Q   S   S   A           E   A   S   A   W   L   L   C   E   V   S   N   F   S 
  NW_001794226 IGHD*01   F   CH7 gDNA   cag tcc tcg gcc ... ... gag gcc tcc gct tgg ctc ttg tgt gag gtc tcc aac ttc tcc
                                                                                                                       
  EU503149     IGHD*02   F   CH7 cDNA   --- --- --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                        _______BC___________________                            _____________CD_________
                                                                                                45.1    45.3    45.5    
                                         30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                         P                   A   E   I   F   L   T   W   W   E   N   E   T   S   V   S 
  NW_001794226 IGHD*01   F   CH7 gDNA   cca ... ... ... ... gct gag atc ttc ctg aca tgg tgg gag aac gag acg agt gtc agc
                                                                                                                       
  EU503149     IGHD*02   F   CH7 cDNA   --- ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                        ____                                ___________________________DE_______________
                                        45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                             77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                         P   S       W   F   T   T   T   A   P   F   A   Q   P   G   N                 
  NW_001794226 IGHD*01   F   CH7 gDNA   ccc tcc ... tgg ttc acc acc acg gcc ccc ttt gcc cag cct gga aat ... ... ... ...
                                                                                                                       
  EU503149     IGHD*02   F   CH7 cDNA   --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ...


                                        ____________                                                ___EF___            
                                            85.2                                                    96.1                
                                        85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                             A   M   Y   S   T   Q   S   L   L   R   I   P   A   S   Q   G           H 
  NW_001794226 IGHD*01   F   CH7 gDNA   ... gcc atg tat tcg acc cag agt ctt ctg cga ata cca gcc tct cag gga ... ... cac
                                                                                                                       
  EU503149     IGHD*02   F   CH7 cDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ---


                                                            _________________________FG_________________________        
                                        
                                        100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                         M   A   S   T   Y   T   C   M   V   G   H   V   S   S   P   S   M   L   N   I 
  NW_001794226 IGHD*01   F   CH7 gDNA   atg gcc tcc aca tat acc tgt atg gtt ggg cat gtc tcc tcc cct agc atg ctc aac atc
                                                                                                                       
  EU503149     IGHD*02   F   CH7 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                                
                                        
                                        120 121 122 123 124 125 
                                         S   R   N   G   V   F  
  NW_001794226 IGHD*01   F   CH7 gDNA   agc agg aat gga gtg ttc 
                                                                
  EU503149     IGHD*02   F   CH7 cDNA   --- --- --- --- --- --- 




                                                                                                                        
                                        
                                        1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                                 D   F   L   E   P   A   R   P   L   V   T   A   F   H 
  NW_001794226 IGHD*01   F   CH8 gDNA                           gat ttc ctg gaa cca gcc cgg cct ctg gtc acc gcc ttc cac
                                                                                                                       
  EU503149     IGHD*02   F   CH8 cDNA                           --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                    _____AB_____                                            ____________
                                                    15.1    15.3                                                        
                                         13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                         E   P   S   G           S   S   R   E   K   L   V   C   L   A   T   D   F   R 
  NW_001794226 IGHD*01   F   CH8 gDNA   gaa ccc agc ggg ... ... agc agt cgg gag aag ctg gtc tgc ctg gcc act gac ttc cgc
                                                                                                                       
  EU503149     IGHD*02   F   CH8 cDNA   --- --- --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                        _______BC___________________                            _____________CD_________
                                                                                                45.1    45.3    45.5    
                                         30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                         P                   K   D   I   D   M   K   W   E   V   R   G   Q   E   R   R 
  NW_001794226 IGHD*01   F   CH8 gDNA   ccc ... ... ... ... aag gac atc gac atg aag tgg gag gtg aga ggt cag gag cgc cgc
                                                                                                                       
  EU503149     IGHD*02   F   CH8 cDNA   --- ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                        ____                                ___________________________DE_______________
                                        45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                             77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                         C           S   D   S   L   P   S   K   A   L   G   N   G                     
  NW_001794226 IGHD*01   F   CH8 gDNA   tgc ... ... agc gat tcc ctc cct agc aag gct cta ggc aat ggc ... ... ... ... ...
                                                                                                                       
  EU503149     IGHD*02   F   CH8 cDNA   --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ...


                                        ____________                                                ___EF___            
                                            85.2                                                    96.1                
                                        85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                                 M   F   Q   Q   S   C   A   L   L   L   S   L   E   E   W           T 
  NW_001794226 IGHD*01   F   CH8 gDNA   ... ... atg ttc cag cag agt tgt gcc ttg ctg tta agt ctg gag gag tgg ... ... acc
                                                                                                                       
  EU503149     IGHD*02   F   CH8 cDNA   ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ---


                                                            _________________________FG_________________________        
                                        
                                        100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                         Q   P   E   T   Y   T   C   V   V   N   H   S   S           D   T   A   A   V 
  NW_001794226 IGHD*01   F   CH8 gDNA   cag ccg gag aca tac acc tgt gtg gtg aac cac agc tcg ... ... gat acg gct gcc gtg
                                                                                                                       
  EU503149     IGHD*02   F   CH8 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- ---


                                                                    
                                        
                                        120 121 122 123 124 125 126 
                                         R   R   E   L   T   S   T  
  NW_001794226 IGHD*01   F   CH8 gDNA   agg agg gag ctg acc tcc acc 
                                                                    
  EU503149     IGHD*02   F   CH8 cDNA   --- --- --- --- --- --- --- 




                                                                                                                        
                                        
                                        1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                     Q   C   P   A   W   S   P   T   A   H   T   L   P   P   S   F   E 
  NW_001794226 IGHD*01   F   CH9 gDNA               cag tgt cca gcc tgg agt ccg acc gcc cac acc cta ccc cca tcc ttc gag
                                                                                                                       
  EU503149     IGHD*02   F   CH9 cDNA               --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                    _____AB_____                                            ____________
                                                    15.1    15.3                                                        
                                         13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                         W   L   L   Q           N   E   T   V   V   L   T   C   V   T   D   M   F     
  NW_001794226 IGHD*01   F   CH9 gDNA   tgg ctg ttg cag ... ... aat gag acg gta gtg ctg aca tgt gtg acc gac atg ttc ...
                                                                                                                       
  EU503149     IGHD*02   F   CH9 cDNA   --- --- --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ...


                                        _______BC___________________                            _____________CD_________
                                                                                                45.1    45.3    45.5    
                                         30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                                                 N   A   S   V   E   W   T   A   G   E   E   L   A   A 
  NW_001794226 IGHD*01   F   CH9 gDNA   ... ... ... ... ... ... aac gcg agt gtg gag tgg acg gca gga gag gag ctg gct gct
                                                                                                                       
  EU503149     IGHD*02   F   CH9 cDNA   ... ... ... ... ... ... --- --- --- --- --- --- --a --- --- --- --- --- --- ---


                                        ____                                ___________________________DE_______________
                                        45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                             77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                         L           E   T   V   E   N   K   K   E   K   F   P   N                     
  NW_001794226 IGHD*01   F   CH9 gDNA   ttg ... ... gag acg gtg gag aac aaa aag gag aaa ttc ccc aat ... ... ... ... ...
                                                                                                                       
  EU503149     IGHD*02   F   CH9 cDNA   --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ...


                                        ____________                                                ___EF___            
                                            85.2                                                    96.1                
                                        85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                             G   S   S   W   L   F   S   Q   L   K   V   N   F   S   V   W           N 
  NW_001794226 IGHD*01   F   CH9 gDNA   ... ggg agt agc tgg ctc ttc agc cag ttg aaa gtc aat ttc agt gtc tgg ... ... aac
                                                                                                                       
  EU503149     IGHD*02   F   CH9 cDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ---


                                                            _________________________FG_________________________        
                                        
                                        100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                         S   T   E   S   F   S   C   Q   V   K   D   G   Q           S   E   L   R   V 
  NW_001794226 IGHD*01   F   CH9 gDNA   agc aca gaa tcc ttc agc tgc cag gtc aag gat ggc cag ... ... agt gaa ctg agg gtc
                                                                                                                       
  EU503149     IGHD*02   F   CH9 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- ---


                                                                
                                        
                                        120 121 122 123 124 125 
                                         N   V   T   H   I   P  
  NW_001794226 IGHD*01   F   CH9 gDNA   aac gtc act cat att ccc 
                                                                
  EU503149     IGHD*02   F   CH9 cDNA   --- --- --- --- --- --- 


                                         
                        
                                         1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                          G   P   V   K   A   P   K   V   Y   L   F   P   P   P   T   E 
  NW_001794226 IGHD*01   F   CH10 gDNA                   ggt cct gtt aag gcc ccc aaa gtt tac ctc ttc ccg ccc ccg act gag
                                                                                                                        
  EU503149     IGHD*02   F   CH10 cDNA                   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                                                  
                                                     _____AB_____                                            ____________
                                                     15.1    15.3                                                        
                                          13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                          E   M   S   R           G   P   S   L   T   L   V   C   L   I   K   D   F   Y 
  NW_001794226 IGHD*01   F   CH10 gDNA   gag atg agt cga ... ... ggt ccc tct ctc acc ttg gtc tgc cta atc aaa gac ttc tac
                                                                                                                        
  EU503149     IGHD*02   F   CH10 cDNA   --- --- --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---

                                                                                 
                                         _______BC___________________                            _____________CD_________
                                                                                                 45.1    45.3    45.5    
                                          30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                          P                   A   S   I   L   V   Q   W   Q   E   G   S   A   V   L   E 
  NW_001794226 IGHD*01   F   CH10 gDNA   cca ... ... ... ... gcc agc atc ctg gtg caa tgg cag gag ggc agt gcg gtg tta gaa
                                                                                                                        
  EU503149     IGHD*02   F   CH10 cDNA   --- ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

                                                                                
                                         ____                                ___________________________DE_______________
                                         45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                              77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                          T   Q   A   A   Q   S   Q   N   P   S   C   D   H   Q   S                     
  NW_001794226 IGHD*01   F   CH10 gDNA   acc caa gct gcc cag agc cag aac cca agc tgt gac cac cag agc ... ... ... ... ...
                                                                                                                        
  EU503149     IGHD*02   F   CH10 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ...

                                                                                
                                         ____________                                                ___EF___            
                                             85.2                                                    96.1                
                                         85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                              R   R   C   S   A   V   S   K   L   E   I   P   K   S   R   W           M 
  NW_001794226 IGHD*01   F   CH10 gDNA   ... cgg agg tgc tct gcg gtc agc aag ctg gag atc ccg aag agc cga tgg ... ... atg
                                                                                                                        
  EU503149     IGHD*02   F   CH10 cDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ---

                                                                                
                                                             _________________________FG_________________________        
                                         
                                         100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                          A   R   T   R   Y   H   C   Q   V   F   H   I   S           R   R   G   I   L 
  NW_001794226 IGHD*01   F   CH10 gDNA   gcc agg acc cga tac cac tgt cag gtg ttc cac atc tcc ... ... cgc aga ggg atc cta
                                                                                                                        
  EU503149     IGHD*02   F   CH10 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- ---

                                                                                
                                                                 
                                         
                                         120 121 122 123 124 125 126 127 
                                          I   R   N   A   S   T   H   Y  
  NW_001794226 IGHD*01   F   CH10 gDNA   atc cga aac gcc agc acc cat tat 
                                                                         
  EU503149     IGHD*02   F   CH10 cDNA   --- --- --- --- --- --- --- --- 

    
                                        ________________CHS_________________
                                        
                                         1   2   3   4   5   6   7   8   9  
                                         D   H   P   A   E   D   S   G   S  
  NW_001794226 IGHD*01   F   CHS gDNA   gac cac cct gca gaa gac tca ggc tcc 



                                                                            
                                        1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                        D   P   R   V   I   D   F   T   F   K   D   E   N   N   D   D   Y   T   E   M 
  NW_001794226 IGHD*01   F   M1 gDNA   gac ccg aga gtg ata gat ttc acc ttc aaa gac gag aac aat gat gat tac acc gag atg
                                                                                                                      
  EU503149     IGHD*02   F   M1 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

                                      
                                      
                                        21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40 
                                        D   E   S   N   N   V   W   P   T   V   S   T   F   V   A   L   F   L   L   T 
  NW_001794226 IGHD*01   F   M1 gDNA   gat gag tcc aac aac gta tgg ccc acc gtg tcc acc ttc gta gcc ctc ttc ctc ctt act
                                                                                                                      
  EU503149     IGHD*02   F   M1 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---                    


                                                                              
                                        41  42  43  44  45  46  47  48  49  50  51 
                                        L   L   Y   S   G   F   V   T   F   I   K  
  NW_001794226 IGHD*01   F   M1 gDNA   ctg ctg tac agt ggt ttc gtc acc ttc atc aag 
                                                                                   


                                      
                                       
                                        1   2  
                                        V   K  
  NW_001794226 IGHD*01   F   M2 gDNA   gtt aag 

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
25/11/2014
Last updated:
27/05/2016
Authors:
Saida Saljoqi