Here you are: IMGT Web resources > IMGT Repertoire > Proteins and alleles

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

	
	
	                                                                                
                                        
                                        1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                         V   S   S   K   A   P   S   V   F   P   L   V   P   C   C   D 
  NW_001794226 IGHE*01   F   CH1 gDNA                   gtc tct agc aaa gcc cct tcg gtc ttc ccc ctg gtg ccc tgc tgt gat
                                                                                                                       
  AY055780     IGHE*02   F   CH1 cDNA                   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                    _____AB_____                                            ____________
                                                    15.1    15.3                                                        
                                         13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                         G   T   D               S   S   A   V   T   L   G   C   L   V   T   G   Y   I 
  NW_001794226 IGHE*01   F   CH1 gDNA   ggc acc gac ... ... ... tcc tca gca gtg acc ctg ggc tgc ctt gtc act ggc tac att
                                                                                                                       
  AY055780     IGHE*02   F   CH1 cDNA   --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                        _______BC___________________                            _____________CD_________
                                                                                                45.1    45.3    45.5    
                                         30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                         P                   E   P   V   T   V   R   W   N   S   G   D   L   V   K     
  NW_001794226 IGHE*01   F   CH1 gDNA   ccc ... ... ... ... gaa ccg gtg acc gtg cgc tgg aac tct gga gac ctg gtc aaa ...
                                                                                                                       
  AY055780     IGHE*02   F   CH1 cDNA   --- ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ...


                                        ____                                ___________________________DE_______________
                                        45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                             77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                                     G   V   T   T   F   P   S   V   F   D   S   Q   S                 
  NW_001794226 IGHE*01   F   CH1 gDNA   ... ... ... ggc gtc aca act ttc ccg tcc gtc ttc gac agc caa agc ... ... ... ...
                                                                                                                       
  AY055780     IGHE*02   F   CH1 cDNA   ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ...


                                        ____________                                                ___EF___            
                                            85.2                                                    96.1                
                                        85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                             G   L   Y   T   M   S   S   Q   V   T   V   S   Q   E   S   W             
  NW_001794226 IGHE*01   F   CH1 gDNA   ... gga ctc tac acc atg agt agt cag gtc act gtg agt caa gag agc tgg ... ... ...
                                                                                                                       
  AY055780     IGHE*02   F   CH1 cDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ...


                                                            _________________________FG_________________________        
                                        
                                        100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                         Q   S   Q   T   F   T   C   N   V   E   Q   T   A   T   K   T   K   I   N   T 
  NW_001794226 IGHE*01   F   CH1 gDNA   caa tcc cag acc ttc acc tgc aac gtg gag cag acg gcc acc aaa acg aag atc aac aca
                                                                                     M                                 
  AY055780     IGHE*02   F   CH1 cDNA   --- --- --- --- --- --- --- --- --- --- --- -t- --- --- --- --- --- --- --- ---


                                                        
                                        
                                        120 121 122 123 
                                         E   V   Y   S  
  NW_001794226 IGHE*01   F   CH1 gDNA   gag gtt tat tca 
                                                        
  AY055780     IGHE*02   F   CH1 cDNA   --- --- --- --- 



                                                                                                                        
                                        
                                        1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                             D   C   S   K   D   P   I   P   P   T   V   K   L   L   H   S   S   C   D 
  NW_001794226 IGHE*01   F   CH2 gDNA       gac tgc tcc aaa gat ccg atc cca ccg acc gtg aag ttg ctc cat tcc tcc tgc gac
                                                                                                                       
  AY055780     IGHE*02   F   CH2 cDNA       --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                    _____AB_____                                            ____________
                                                    15.1    15.3                                                        
                                         13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                         P   R   G   D   S       Q   A   S   I   E   L   L   C   L   I   T   S   Y   S 
  NW_001794226 IGHE*01   F   CH2 gDNA   ccc cgc ggg gac tct ... cag gcg agc att gag tta ctg tgc ctc atc acc agc tac tcg
                                                                                                             G         
  AY055780     IGHE*02   F   CH2 cDNA   --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- g-- --- ---


                                        _______BC___________________                            _____________CD_________
                                                                                                45.1    45.3    45.5    
                                         30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                         P                   A   G   I   Q   V   D   W   L   V   D   G   Q   K   A   E 
  NW_001794226 IGHE*01   F   CH2 gDNA   cca ... ... ... ... gcg ggc atc cag gta gac tgg ctg gtg gac ggg cag aag gct gaa
                                                                                                                       
  AY055780     IGHE*02   F   CH2 cDNA   --- ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                        ____                                ___________________________DE_______________
                                        45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                             77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                         N           L   F   P   Y   T   A   P   P   K   R   E   G   N                 
  NW_001794226 IGHE*01   F   CH2 gDNA   aac ... ... ctc ttc ccc tac acg gct cca ccg aag aga gag ggc aac ... ... ... ...
                                                                                                                       
  AY055780     IGHE*02   F   CH2 cDNA   --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ...


                                        ____________                                                ___EF___            
                                            85.2                                                    96.1                
                                        85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                             R   S   F   S   S   H   S   E   V   N   I   T   Q   D   Q   W           L 
  NW_001794226 IGHE*01   F   CH2 gDNA   ... agg agc ttc tcc tcc cat agc gag gtc aac atc acc cag gat cag tgg ... ... ctg
                                                                                                                       
  AY055780     IGHE*02   F   CH2 cDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ---


                                                            _________________________FG_________________________        
                                        
                                        100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                         S   G   K   T   F   T   C   Q   V   T   H   L   A           D   K   K   T   Y 
  NW_001794226 IGHE*01   F   CH2 gDNA   tcc ggc aag acc ttc acc tgc caa gtc acc cac ctg gcc ... ... gac aaa aaa acc tac
                                                                                                                       
  AY055780     IGHE*02   F   CH2 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- ---


                                                                        
                                        
                                        120 121 122 123 124 125 126 127 
                                         Q   D   S   A   R   K   C   A  
  NW_001794226 IGHE*01   F   CH2 gDNA   caa gac agt gcc agg aag tgt gca 
                                                                        
  AY055780     IGHE*02   F   CH2 cDNA   --- --- --- --- --- --- --- --- 



                                                                                                                        
                                        
                                        1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                     D   S   D   P   R   G   I   T   V   F   L   T   P   P   S   P   T 
  NW_001794226 IGHE*01   F   CH3 gDNA               gat tca gac ccc cgt ggc atc acc gtc ttt ctg acc cca cca agc ccc act
                                                                                                                       
  AY055780     IGHE*02   F   CH3 cDNA               --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                    _____AB_____                                            ____________
                                                    15.1    15.3                                                        
                                         13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                         D   L   Y   I           S   K   T   P   K   L   T   C   L   I   I   D   L   V 
  NW_001794226 IGHE*01   F   CH3 gDNA   gac ctc tac atc ... ... tcc aag acc ccc aaa ctg acc tgt ctg atc atc gac ctg gtc
                                                                                                                       
  AY055780     IGHE*02   F   CH3 cDNA   --- --- --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                        _______BC___________________                            _____________CD_________
                                                                                                45.1    45.3    45.5    
                                         30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                         S   T               E   G   M   E   V   T   W   S   R   E   S   G   T   P   L 
  NW_001794226 IGHE*01   F   CH3 gDNA   agc acc ... ... ... gaa ggc atg gag gtc acc tgg tcc cgg gag agt ggt act ccg ctg
                                                                                                                       
  AY055780     IGHE*02   F   CH3 cDNA   --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                        ____                                ___________________________DE_______________
                                        45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                             77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                                     S   A   E   S   F   E   E   Q   K   Q   F   N                     
  NW_001794226 IGHE*01   F   CH3 gDNA   ... ... ... agc gcc gaa tcc ttt gag gaa caa aag cag ttc aac ... ... ... ... ...
                                                                                                                       
  AY055780     IGHE*02   F   CH3 cDNA   ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ...


                                        ____________                                                ___EF___            
                                            85.2                                                    96.1                
                                        85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                             G   T   M   S   F   I   S   T   V   P   V   N   I   Q   D   W           N 
  NW_001794226 IGHE*01   F   CH3 gDNA   ... ggc acc atg agc ttc atc agt act gtc cct gtg aac att cag gac tgg ... ... aat
                                                                                                                       
  AY055780     IGHE*02   F   CH3 cDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ---


                                                            _________________________FG_________________________        
                                        
                                        100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                         E   G   E   S   Y   T   C   R   V   A   H   P   D           L   P   S   P   I 
  NW_001794226 IGHE*01   F   CH3 gDNA   gag ggc gag tca tac acc tgc aga gtg gca cac cca gac ... ... cta cct tcc ccc atc
                                                                                                                       
  AY055780     IGHE*02   F   CH3 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- ---


                                                                        
                                        
                                        120 121 122 123 124 125 126 127 
                                         I   K   T   V   T   K   L   P  
  NW_001794226 IGHE*01   F   CH3 gDNA   atc aag acc gtg acc aag ctc cca 
                                                                        
  AY055780     IGHE*02   F   CH3 cDNA   --- --- --- --- --- --- --- --- 




                                                                                                                           
                                            
                                            1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                             G   K   R   L   A   P   E   V   Y   A   F   P   P   H   Q   A 
  NW_001794226 IGHE*01   F   CH4-CHS gDNA                   ggc aaa cgt ctg gct ccc gaa gtg tat gcc ttc ccc ccg cac caa gcg
                                                                                                                           
  AY055780     IGHE*02   F   CH4-CHS cDNA                   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                        _____AB_____                                            ____________
                                                        15.1    15.3                                                        
                                             13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                             E   V   S   H           G   D   S   L   S   L   T   C   L   I   R   G   F   Y 
  NW_001794226 IGHE*01   F   CH4-CHS gDNA   gaa gtg tcc cat ... ... ggg gac tcc ctc agc ctg acc tgc ctg atc aga ggc ttc tac
                                                                                                                           
  AY055780     IGHE*02   F   CH4-CHS cDNA   --- --- --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                            _______BC___________________                            _____________CD_________
                                                                                                    45.1    45.3    45.5    
                                             30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                             P                   E   N   I   S   V   R   W   L   L   D   N   K   P   L   P 
  NW_001794226 IGHE*01   F   CH4-CHS gDNA   cct ... ... ... ... gag aac atc agt gtg cgg tgg ctc ctt gac aat aag cct ctc ccc
                                                                                                                           
  AY055780     IGHE*02   F   CH4-CHS cDNA   --- ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                            ____                                ___________________________DE_______________
                                            45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                                 77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                             T   E       H   Y   R   T   T   K   P   L   K   D   Q   G   P                 
  NW_001794226 IGHE*01   F   CH4-CHS gDNA   acc gag ... cat tac agg acc aca aag ccc ctc aag gat caa ggc ccg ... ... ... ...
                                                                                                                           
  AY055780     IGHE*02   F   CH4-CHS cDNA   --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ...


                                            ____________                                                ___EF___            
                                                85.2                                                    96.1                
                                            85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                             D   P   A   Y   F   L   Y   S   R   L   A   V   N   K   S   T   W           E 
  NW_001794226 IGHE*01   F   CH4-CHS gDNA   gat ccc gcc tac ttc ctc tac agc cgg ctg gcc gtc aac aag tcc acc tgg ... ... gag
                                                                                                                           
  AY055780     IGHE*02   F   CH4-CHS cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ---


                                                                _________________________FG_________________________        
                                            
                                            100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                             Q   G   N   V   Y   T   C   Q   V   V   H   E   A   L   P   S   R   N   T   E 
  NW_001794226 IGHE*01   F   CH4-CHS gDNA   caa gga aat gtc tac acc tgc caa gtt gtc cat gag gcc ttg ccc tcc cgc aac act gaa
                                                                                                                           
  AY055780     IGHE*02   F   CH4-CHS cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                                                         __CHS__
                                           
                                            120 121 122 123 124 125 126 127 128 129 130 131 132 
                                             R   K   F   Q   H   T   S                   G   N  
  NW_001794226 IGHE*01   F   CH4-CHS gDNA   cgc aaa ttc cag cac aca tcc ... ... ... ... ggt aac 
                                                                                                
  AY055780     IGHE*02   F   CH4-CHS cDNA   --- --- --- --- --- --- --- ... ... ... ... --- --- 



                                     
                                        1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                        D   L   I   R   E   D   D   C   S   E   A   E   N   E   E   L   D   G   L   W 
  NW_001794226 IGHE*01   F   M1 gDNA   gat ctg atc cga gaa gat gac tgt tcg gag gca gag aat gag gag ctg gat ggg ctg tgg


                                       
                                       
                                        21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40 
                                        T   T   I   Y   V   F   I   T   L   F   L   L   S   V   G   Y   S   A   T   V 
  NW_001794226 IGHE*01   F   M1 gDNA   acc acc atc tat gtc ttc atc acc ctc ttc ctc ctc agc gtg ggc tac agt gcc acg gtc


                                       
                                       
                                        41  42  43  44 
                                        T   L   F   K  
  NW_001794226 IGHE*01   F   M1 gDNA   acc ctg ttc aag 

                                     
                                       
                                        1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                        V   K   W   I   F   A   T   V   L   Q   L   K   R   S   N   V   H   D   Y   K 
  NW_001794226 IGHE*01   F   M2 gDNA   gtg aag tgg atc ttt gcc acg gtg ctg cag ctg aag cgg tcc aac gtc cac gac tac aag


                                       
                                       
                                        21  22  23  24  25  26  27 
                                        N   M   I   Q   Q   G   A  
  NW_001794226 IGHE*01   F   M2 gDNA   aac atg atc cag cag gga gcc 

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
25/11/2014
Last updated:
27/05/2016
Authors:
Saida Saljoqi