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When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

	
	
	                                                                                
                                         
                                         1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                                      V   P   P   S   I   F   P   L   T   P   S   C   K 
  NW_001794226 IGHG1*01   F   CH1 gDNA                               gtt ccc cca tcc atc ttc ccc ttg act ccc agc tgc aaa

  AY055781     IGHG1*02   F   CH1 gDNA                               --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                     _____AB_____                                            ____________
                                                     15.1    15.3                                                        
                                          13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                          E   E   E               L   S   E   V   T   V   G   C   L   V   T   G   Y   S 
  NW_001794226 IGHG1*01   F   CH1 gDNA   gaa gaa gaa ... ... ... ctc tct gag gtg acc gtg ggt tgc cta gtg acc ggc tac tcc

  AY055781     IGHG1*02   F   CH1 gDNA   --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---  


                                         _______BC___________________                            _____________CD_________
                                                                                                 45.1    45.3    45.5    
                                          30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                          P                   Q   P   V   H   V   K   W   S   P   P   A   F   S   S     
  NW_001794226 IGHG1*01   F   CH1 gDNA   cca ... ... ... ... caa cca gtg cac gtc aag tgg agc cca cct gcc ttc agc agc ...

  AY055781     IGHG1*02   F   CH1 gDNA   --- ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ...  


                                         ____                                ___________________________DE_______________
                                         45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                              77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                                      S   S   K   T   F   P   A   V   L   Q   S   G                     
  NW_001794226 IGHG1*01   F   CH1 gDNA   ... ... ... agc tcc aaa acc ttc ccc gct gtc ctc cag tcc ggg ... ... ... ... ...

  AY055781     IGHG1*02   F   CH1 gDNA   ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ...  


                                         ____________                                                ___EF___            
                                             85.2                                                    96.1                
                                         85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                              G   L   Y   T   L   S   S   Q   I   T   L   P   T   E   K   W             
  NW_001794226 IGHG1*01   F   CH1 gDNA   ... ggt ctg tac acc ctc agc agc caa atc acc ctc cct aca gaa aaa tgg ... ... ...

  AY055781     IGHG1*02   F   CH1 gDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ...  


                                                             _________________________FG_________________________        
                                         
                                         100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                          R   S   E   S   V   T   C   N   V   E   H   P   A           S   K   T   K   I 
  NW_001794226 IGHG1*01   F   CH1 gDNA   cgg tcg gag tca gtc act tgc aat gtg gag cac cca gcc ... ... agc aag acc aag atc

  AY055781     IGHG1*02   F   CH1 gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- ---  


                                                         
                                         
                                         120 121 122 123 
                                          D   K   K   V  
  NW_001794226 IGHG1*01   F   CH1 gDNA   gat aag aaa gtt 

  AY055781     IGHG1*02   F   CH1 gDNA   --- --- --- ---   


                                       
                                        1   2   3   4   5   6   7   8   9   10  11 
                                        E   P   G   P   S   N   P   P   H   C   P  
  NW_001794226 IGHG1*01   F   H gDNA   gaa cct gga cct agt aac cct cct cac tgc cca 

  AY055781     IGHG1*02   F   H gDNA   --- --- --- --- --- --- --- --- --- --- --- aac cca


                                                                                                                         
                                         
                                         1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                                      S   S   A   A   V   F   I   F   P   P   K   P   K 
  NW_001794226 IGHG1*01   F   CH2 gDNA                               agt agt gct gct gta ttc ata ttc cct ccc aaa ccc aag
                                                                      G
  AY055781     IGHG1*02   F   CH2 gDNA                               g-- --- --- --- --- --- --- --- --- --- --- --- ---

                                                     _____AB_____                                            ____________
                                                     15.1    15.3                                                        
                                          13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                          D   F   L   S   V       A   G   T   P   K   V   T   C   V   V   V   D   L   G 
  NW_001794226 IGHG1*01   F   CH2 gDNA   gac ttc ctc tct gtg ... gct ggc acc cct aag gtc acc tgt gtt gtt gtg gat ctt ggc

  AY055781     IGHG1*02   F   CH2 gDNA   --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                         _______BC___________________                            _____________CD_________
                                                                                                 45.1    45.3    45.5    
                                          30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                          F   E   D   K   D   E   S   P   V   V   T   W   Y   Q   G   D   K   E   L   P 
  NW_001794226 IGHG1*01   F   CH2 gDNA   ttc gaa gac aaa gat gaa agc cct gtt gtc act tgg tac caa ggc gac aag gaa ctt ccc

  AY055781     IGHG1*02   F   CH2 gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                         ____                                ___________________________DE_______________
                                         45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                              77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                                      K   T   R   M   L   E   P   P   P   K   E   Q   R                 
  NW_001794226 IGHG1*01   F   CH2 gDNA   ... ... ... aag aca aga atg cta gaa cca cca ccc aag gaa cag agg ... ... ... ...

  AY055781     IGHG1*02   F   CH2 gDNA   ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ...


                                         ____________                                                ___EF___            
                                             85.2                                                    96.1                
                                         85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                          N   G   T   Y   R   F   V   S   E   R   D   V   S   S   K   D   W           L 
  NW_001794226 IGHG1*01   F   CH2 gDNA   aat ggc acc tat cgt ttc gtc agt gag cgg gac gtg tcc agc aag gac tgg ... ... ctg

  AY055781     IGHG1*02   F   CH2 gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ---


                                                             _________________________FG_________________________        
                                         
                                         100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                          D   Q   K   V   F   K   C   K   V   Q   H   K   N           F   P   S   P   I 
  NW_001794226 IGHG1*01   F   CH2 gDNA   gac cag aaa gta ttc aaa tgc aaa gtg caa cac aaa aat ... ... ttt cca tca ccc atc

  AY055781     IGHG1*02   F   CH2 gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- ---


                                                                         
                                         
                                         120 121 122 123 124 125 126 127 
                                          T   K   S   I   S   H   T   A  
  NW_001794226 IGHG1*01   F   CH2 gDNA   acg aag tct atc tcc cat act gcc 

  AY055781     IGHG1*02   F   CH2 gDNA   --- --- --- --- --- --- --- --- 



                                                                                                                             
                                             
                                             1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                              G   T   R   K   A   P   E   A   Y   V   F   P   P   H   R   D 
  NW_001794226 IGHG1*01   F   CH3-CHS gDNA                   ggc aca cgc aaa gct ccg gag gcc tac gtc ttc cca cct cac cga gat

  AY055781     IGHG1*02   F   CH3-CHS gDNA                   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                         _____AB_____                                            ____________
                                                         15.1    15.3                                                        
                                              13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                              E   M   N               K   N   S   V   S   I   T   C   L   V   L   D   F   Y 
  NW_001794226 IGHG1*01   F   CH3-CHS gDNA   gag atg aac ... ... ... aaa aac tct gtg agc atc acc tgt ttg gtc ttg gac ttc tac

  AY055781     IGHG1*02   F   CH3-CHS gDNA   --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                             _______BC___________________                            _____________CD_________
                                                                                                     45.1    45.3    45.5    
                                              30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                              P                   D   A   I   A   I   D   W   Q   H   N   D   R   P   V   P 
  NW_001794226 IGHG1*01   F   CH3-CHS gDNA   ccc ... ... ... ... gat gca atc gcc atc gac tgg caa cat aac gac aga ccg gta cct

  AY055781     IGHG1*02   F   CH3-CHS gDNA   --- ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                             ____                                ___________________________DE_______________
                                             45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                                  77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                                          E   G   D   Y   A   T   T   L   P   Q   K   N                     
  NW_001794226 IGHG1*01   F   CH3-CHS gDNA   ... ... ... gag gga gac tat gcc acc acc ctg ccc cag aaa aat ... ... ... ... ...

  AY055781     IGHG1*02   F   CH3-CHS gDNA   ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ...


                                             ____________                                                ___EF___            
                                                 85.2                                                    96.1                
                                             85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                              G   N   S   Y   F   L   Y   S   K   L   T   V   Q   K   T   E   W           N 
  NW_001794226 IGHG1*01   F   CH3-CHS gDNA   ggg aac tcc tac ttc ctc tac agc aag ctt act gtg cag aag aca gaa tgg ... ... aat

  AY055781     IGHG1*02   F   CH3-CHS gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ---


                                                                 _________________________FG_________________________        
                                             
                                             100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                              Q   G   G   S   F   T   C   S   V   R   H   E   A       L   P   Q   K   F   L 
  NW_001794226 IGHG1*01   F   CH3-CHS gDNA   caa gga ggc tcc ttt acc tgc tca gtg agg cac gag gcc ... ctg ccc cag aaa ttt ctt

  AY055781     IGHG1*02   F   CH3-CHS gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- ---


                                                                                        ___CHS___
                                             
                                             120 121 122 123 124 125 126 127 128 129 130 131 132 
                                              Q   K   T   V   S   K   T   S               G   K  
  NW_001794226 IGHG1*01   F   CH3-CHS gDNA   cag aag acg gtg tcc aaa act tcc ... ... ... ggt aaa 

  AY055781     IGHG1*02   F   CH3-CHS gDNA   --- --- --- --- --- --- --- --- ... ... ... --- --- 


                                       
                                         1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                         E   L   I   L   D   E   N   C   A   E   A   G   D   E   E   L   E   G   L   W 
  NW_001794226 IGHG1*01   F   M1 gDNA   gag ctg att ctg gat gag aac tgt gct gag gct gga gat gag gaa ctc gaa ggg cta tgg


                                        
                                        
                                         21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40 
                                         T   T   I   S   V   F   I   T   L   F   F   L   S   V   C   Y   S   A   T   V 
  NW_001794226 IGHG1*01   F   M1 gDNA   acc acc atc tct gtc ttc atc acc ctc ttc ttc ctc agc gtg tgt tac agt gcc aca gtc


                                        
                                        
                                         41  42  43  44 
                                         T   L   F   K  
  NW_001794226 IGHG1*01   F   M1 gDNA   acc ctt ttc aag 


                                        
                                        
                                         1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                         V   K   W   I   F   S   T   V   V   D   L   K   P   Q   M   L   P   D   Y   R 
  NW_001794226 IGHG1*01   F   M2 gDNA   gtg aag tgg atc ttc tcc aca gtg gtg gac ttg aag ccg caa atg ctt ccc gat tac cgg


                                        
                                        
                                         21  22  23  24  25  26  27 
                                         N   M   I   D   Q   G   A  
  NW_001794226 IGHG1*01   F   M2 gDNA   aac atg att gat caa ggg gcc 

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
25/11/2014
Last updated:
27/05/2016
Authors:
Saida Saljoqi