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When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

	
	
	                                                                                                                        
                                         
                                         1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                          X   A   K   V   S   P   T   V   Y   P   L   I   P   S   R   K 
  NW_001705893 IGHG2*01   F   CH1 gDNA                   nct gcg aaa gtg tct ccg acc gtc tac ccc ttg att ccc agc cgc aag
                                                          A                                                             
  AY055782     IGHG2*01   F   CH1 cDNA                   g-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                     _____AB_____                                            ____________
                                                     15.1    15.3                                                        
                                          13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                          E   K   N               L   S   Q   V   T   L   G   C   L   V   T   G   Y   F 
  NW_001705893 IGHG2*01   F   CH1 gDNA   gag aaa aac ... ... ... ctc tcc caa gtg acc ctg ggc tgc ctg gtg act ggc tac ttt
                                                                                                                        
  AY055782     IGHG2*01   F   CH1 cDNA   --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                         _______BC___________________                            _____________CD_________
                                                                                                 45.1    45.3    45.5    
                                          30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                          P                   E   P   V   S   I   K   W   S   P   E   T   F   S   S     
  NW_001705893 IGHG2*01   F   CH1 gDNA   cca ... ... ... ... gaa ccg gtg agc atc aag tgg agc ccg gag act ttc agc agc ...
                                                                                                                        
  AY055782     IGHG2*01   F   CH1 cDNA   --- ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ...


                                         ____                                ___________________________DE_______________
                                         45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                              77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                                      N   S   K   T   F   P   A   I   L   Q   P   S                     
  NW_001705893 IGHG2*01   F   CH1 gDNA   ... ... ... aac tcc aaa acc ttc cct gct atc ctc cag ccc agt ... ... ... ... ...
                                                                                                                        
  AY055782     IGHG2*01   F   CH1 cDNA   ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ...


                                         ____________                                                ___EF___            
                                             85.2                                                    96.1                
                                         85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                              G   L   Y   T   L   S   S   Q   I   T   V   P   E   D   N   W             
  NW_001705893 IGHG2*01   F   CH1 gDNA   ... ggt cta tac acc ctc agc agc caa atc acc gtc cct gaa gat aat tgg ... ... ...
                                                                                                                        
  AY055782     IGHG2*01   F   CH1 cDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ...


                                                             _________________________FG_________________________        
                                         
                                         100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                          C   G   E   L   F   T   C   S   V   E   H   P   A           T   Q   K   N   T 
  NW_001705893 IGHG2*01   F   CH1 gDNA   tgt ggc gag ttg ttc act tgc agt gta gaa cac cct gcc ... ... acc cag aag aac acc
                                                                                                                        
  AY055782     IGHG2*01   F   CH1 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- ---


                                                         
                                         
                                         120 121 122 123 
                                          Q   K   T   V  
  NW_001705893 IGHG2*01   F   CH1 gDNA   caa aaa aca gtc 
                                                         
  AY055782     IGHG2*01   F   CH1 cDNA   --- --- --- --- 



                                       
                                       
                                        1   2   3   4   5   6   7   8   9   10  11 
                                        G   P   R   F   P   G   S   N   S   C   P  
  NW_001705893 IGHG2*01   F   H gDNA   gga cct aga ttt cct gga tca aat tca tgc cca 
                                                                                   
  AY055782     IGHG2*01   F   H cDNA   --- --- --- --- --- --- --- --- --- --- --- 
                                                                                                                         
                                         
                                         1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                              V   L   C   G   P   A   V   F   L   V   P   P   R   P   K 
  NW_001705893 IGHG2*01   F   CH2 gDNA                       gtt tta tgc gga cct gca gta ttc cta gtc cct cca aga ccc aag
                                                                                                                        
  AY055782     IGHG2*01   F   CH2 cDNA                   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                     _____AB_____                                            ____________
                                                     15.1    15.3                                                        
                                          13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                          D   L   L   S   E       G   G   K   P   K   I   I   C   V   A   T   G   L   R 
  NW_001705893 IGHG2*01   F   CH2 gDNA   gac tta ctc tct gaa ... ggt ggc aaa ccc aag atc atc tgc gtg gcc act ggt ctc agg
                                                                                                                        
  AY055782     IGHG2*01   F   CH2 cDNA   --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                         _______BC___________________                            _____________CD_________
                                                                                                 45.1    45.3    45.5    
                                          30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                          D   E           E   K   D   A   R   V   K   W   Y   K   N   G   T   L   F   P 
  NW_001705893 IGHG2*01   F   CH2 gDNA   gat gag ... ... gaa aaa gat gct aga gta aag tgg tac aaa aat gga aca ctg ttt ccc
                                                                                                                        
  AY055782     IGHG2*01   F   CH2 cDNA   --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                         ____                                ___________________________DE_______________
                                         45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                              77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                                      N   S   Q   N   A   Q   T   S   S   D   T   I   W                 
  NW_001705893 IGHG2*01   F   CH2 gDNA   ... ... ... aac tcg caa aac gca cag acg tca tca gat aca ata tgg ... ... ... ...
                                                                                                                        
  AY055782     IGHG2*01   F   CH2 cDNA   ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ...


                                         ____________                                                ___EF___            
                                             85.2                                                    96.1                
                                         85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                              N   G   T   R   V   S   S   K   L   S   V   T   P   E   D   W           K 
  NW_001705893 IGHG2*01   F   CH2 gDNA   ... aat ggc aca cgt gtt tcc agt aag ctg tca gtg acc cct gag gac tgg ... ... aag
                                                                                                                        
  AY055782     IGHG2*01   F   CH2 cDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ---


                                                             _________________________FG_________________________        
                                         
                                         100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                          S   D   A   E   F   R   C   E   V   E   H   K   L           F   P   T   S   L 
  NW_001705893 IGHG2*01   F   CH2 gDNA   agt gat gca gag ttc aga tgt gaa gta gaa cac aaa tta ... ... ttt cca aca tca ttg
                                                                                                                        
  AY055782     IGHG2*01   F   CH2 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- ---


                                                                         
                                         
                                         120 121 122 123 124 125 126 127 
                                          K   K   A   I   S   H   D   K  
  NW_001705893 IGHG2*01   F   CH2 gDNA   aaa aaa gca atc tcc cat gat aaa 
                                                                         
  AY055782     IGHG2*01   F   CH2 cDNA   --- --- --- --- --- --- --- --- 
                                                                                                                             
                                             
                                             1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                          N   T   E   R   K   T   P   E   A   Y   I   F   S   P   H   T   E 
  NW_001705893 IGHG2*01   F   CH3-CHS gDNA               aac act gaa cgt aaa acc cca gag gcc tac atc ttc tca cca cac acg gag
                                                                                                                            
  AY055782     IGHG2*01   F   CH3-CHS cDNA               --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                         _____AB_____                                            ____________
                                                         15.1    15.3                                                        
                                              13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                              E   L   S               K   E   S   V   S   I   T   C   L   V   K   G   F   L 
  NW_001705893 IGHG2*01   F   CH3-CHS gDNA   gag ctg agc ... ... ... aag gaa tct gtg agc atc acc tgt ctg gtc aag ggc ttc tta
                                                                                                                            
  AY055782     IGHG2*01   F   CH3-CHS cDNA   --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                             _______BC___________________                            _____________CD_________
                                                                                                     45.1    45.3    45.5    
                                              30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                              P                   Q   D   I   S   I   A   W   Q   H   K   G   K   E   M   K 
  NW_001705893 IGHG2*01   F   CH3-CHS gDNA   ccc ... ... ... ... caa gat atc tcc att gcg tgg caa cat aaa ggc aaa gaa atg aag
                                                                                                                            
  AY055782     IGHG2*01   F   CH3-CHS cDNA   --- ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                             ____                                ___________________________DE_______________
                                             45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                                  77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                                          E   E   E   Y   S   T   T   P   P   Q   Y   R                     
  NW_001705893 IGHG2*01   F   CH3-CHS gDNA   ... ... ... gag gaa gag tac tct acc acc cca ccc cag tat cga ... ... ... ... ...
                                                                                                                            
  AY055782     IGHG2*01   F   CH3-CHS cDNA   ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ...


                                             ____________                                                ___EF___            
                                                 85.2                                                    96.1                
                                             85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                              N   G   S   Y   F   L   Y   S   K   L   T   V   T   K   K   D   W           E 
  NW_001705893 IGHG2*01   F   CH3-CHS gDNA   aat ggc tcc tac ttt ctg tat agc aag ctt act gtg aca aag aag gat tgg ... ... gaa
                                                                                                                            
  AY055782     IGHG2*01   F   CH3-CHS cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ---


                                                                 _________________________FG_________________________        
                                             
                                             100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                              T   G   E   S   F   S   C   L   V   Y   H   D   S           R   S   D   T   L 
  NW_001705893 IGHG2*01   F   CH3-CHS gDNA   aca gga gag tct ttc tcc tgc ttg gtg tac cat gac tcc ... ... cgg tca gac aca ctg
                                                                                                                            
  AY055782     IGHG2*01   F   CH3-CHS cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- ---


                                                                                 ______CHS_______
                                             
                                             120 121 122 123 124 125 126 127 128 129 130 131 132 
                                              K   K   T   V   S   K   N   T               G   N  
  NW_001705893 IGHG2*01   F   CH3-CHS gDNA   aaa aag acg gtg tcc aaa aat act ... ... ... ggt aat 
                                                                                                 
  AY055782     IGHG2*01   F   CH3-CHS cDNA   --- --- --- --- --- --- --- --- ... ... ... --- --- 
                                        
                                        
                                         1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                         G   L   I   L   D   E   N   C   T   E   A   D   S   E   E   L   E   G   L   W 
  NW_001705893 IGHG2*01   F   M1 gDNA   ggg ctt att ctg gat gag aac tgc acc gag gct gac agt gag gaa ctt gaa ggg ctg tgg

                                       
                                       
                                         21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40 
                                         T   T   I   S   V   F   I   T   L   F   F   L   S   V   C   Y   S   A   T   I 
  NW_001705893 IGHG2*01   F   M1 gDNA   acc acc atc tct gtc ttc atc acc ctc ttc ttc ctc agc gtg tgc tac agt gcc acg atc

                                       
                                      
                                         41  42  43  44 
                                         T   L   F   K  
  NW_001705893 IGHG2*01   F   M1 gDNA   acc ctg ttc aag 
                                        
                                        
                                         1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                         V   K   W   I   Y   S   S   V   V   Q   L   K   P   Q   M   L   P   D   Y   R 
  NW_001705893 IGHG2*01   F   M2 gDNA   gtg aaa tgg att tac tcc tcg gtg gtg cag ttg aag cca caa atg cta ccc gac tac agg


                                        
                                        
                                         21  22  23  24  25  26  27 
                                         N   M   I   N   H   E   V  
  NW_001705893 IGHG2*01   F   M2 gDNA   aac atg att aat cac gag gtc 

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
25/11/2014
Last updated:
27/05/2016
Authors:
Saida Saljoqi