Here you are: IMGT Web resources > IMGT Repertoire > Proteins and alleles

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

	
	
	                                                                                
                                        
                                        1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                         A   S   Q   Q   A   P   L   L   F   P   L   V   P   S   C   G 
  NW_001794226 IGHM*01   F   CH1 gDNA                   gct tca caa caa gcc cca ctt ctc ttc cct ctc gtc ccc tcc tgt ggg
                                                                                                                       
  AY168639     IGHM*01   F   CH1 cDNA                   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                    _____AB_____                                            ____________
                                                    15.1    15.3                                                        
                                         13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                         D   S   L   N   Q       E   S   S   L   A   V   G   C   L   A   K   N   F   L 
  NW_001794226 IGHM*01   F   CH1 gDNA   gat tcc cta aac caa ... gaa agc tca ctg gcc gtg ggg tgc ctg gcc aag aac ttc ctg
                                                                                                                       
  AY168639     IGHM*01   F   CH1 cDNA   --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                        _______BC___________________                            _____________CD_________
                                                                                                45.1    45.3    45.5    
                                         30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                         P                   N   S   I   T   L   S   W   D   F   K   N   R   T   T   V 
  NW_001794226 IGHM*01   F   CH1 gDNA   ccc ... ... ... ... aac tcc atc acc ctc tcc tgg gac ttc aag aac aga acc act gtg
                                                                                                                       
  AY168639     IGHM*01   F   CH1 cDNA   --- ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                        ____                                ___________________________DE_______________
                                        45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                             77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                         G           T   E   K   F   I   N   Y   P   T   V   L   S   G                 
  NW_001794226 IGHM*01   F   CH1 gDNA   ggg ... ... act gag aaa ttc ata aac tac ccg aca gtc ctt agt gga ... ... ... ...
                                                                                                                       
  AY168639     IGHM*01   F   CH1 cDNA   --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ...


                                        ____________                                                ___EF___            
                                            85.2                                                    96.1                
                                        85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                             Q   A   Y   S   T   T   S   Q   L   M   I   S   A   T   E   V   M   M   G 
  NW_001794226 IGHM*01   F   CH1 gDNA   ... caa gcc tat tcc acg acc tcc caa ctg atg atc tct gcc acc gaa gtc atg atg ggg
                                                                                                                       
  AY168639     IGHM*01   F   CH1 cDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                            _________________________FG_________________________        
                                        
                                        100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                         Q   D   D   Y   V   F   C   K   A   K   H   A                   V   G   N   K 
  NW_001794226 IGHM*01   F   CH1 gDNA   cag gac gac tac gtg ttc tgc aag gct aag cat gct ... ... ... ... gtg ggg aac aag
                                                                                                                       
  AY168639     IGHM*01   F   CH1 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- --- --- ---


                                                                    
                                        
                                        120 121 122 123 124 125 126 
                                         E   I   R   V   P   L   R  
  NW_001794226 IGHM*01   F   CH1 gDNA   gaa atc aga gtg ccc ctc aga 
                                                                    
  AY168639     IGHM*01   F   CH1 cDNA   --- --- --- --- --- --- --- 





                                                                                                                        
                                        
                                        1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                     V   A   Q   P   S   R   P   N   V   S   L   H   I   P   T   R   E 
  NW_001794226 IGHM*01   F   CH2 gDNA               gtc gcc cag ccc agt agg ccc aac gtg agc ctc cac ata ccc act cgg gaa
                                                                                                                       
  AY168639     IGHM*01   F   CH2 cDNA               --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                    _____AB_____                                            ____________
                                                    15.1    15.3                                                        
                                         13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                         E   F   L   G   P       E   L   E   G   T   I   I   C   Q   A   K   H   F   N 
  NW_001794226 IGHM*01   F   CH2 gDNA   gaa ttc ctg ggt cct ... gaa ctg gag ggc acc atc atc tgt cag gcc aag cac ttc aac
                                                                                                                       
  AY168639     IGHM*01   F   CH2 cDNA   --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                        _______BC___________________                            _____________CD_________
                                                                                                45.1    45.3    45.5    
                                         30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                         P                   K   E   I   S   L   K   W   L   K   N   G   E   L   L   N 
  NW_001794226 IGHM*01   F   CH2 gDNA   ccc ... ... ... ... aag gaa att tcc ctc aag tgg ctg aag aac ggg gag ctg ctc aat
                                                                                                                       
  AY168639     IGHM*01   F   CH2 cDNA   --- ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                        ____                                ___________________________DE_______________
                                        45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                             77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                         G           G   F   T   T   E   G   P   T   L   D   G   S                     
  NW_001794226 IGHM*01   F   CH2 gDNA   ggt ... ... ggc ttc acc acc gag ggc ccc aca ctc gac ggt tcc ... ... ... ... ...
                                                                                                                       
  AY168639     IGHM*01   F   CH2 cDNA   --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ...


                                        ____________                                                ___EF___            
                                            85.2                                                    96.1                
                                        85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                             K   T   Y   Q   L   S   S   S   L   T   V   S   D   T   D   W           F 
  NW_001794226 IGHM*01   F   CH2 gDNA   ... aaa acc tac caa ctc tcc agc tcc ctg aca gta agc gat acc gac tgg ... ... ttc
                                                                                                                       
  AY168639     IGHM*01   F   CH2 cDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ---


                                                            _________________________FG_________________________        
                                        
                                        100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                         K   A   T   D   F   T   C   V   V   E   H   P                   K   T   H   F 
  NW_001794226 IGHM*01   F   CH2 gDNA   aag gcc acc gac ttc acc tgt gtc gtg gaa cat ccg ... ... ... ... aag acc cac ttc
                                                                                                                       
  AY168639     IGHM*01   F   CH2 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- --- --- ---


                                                                             
                                        
                                        120 121 122 123 124 125 126 127 128 129 130 131 
                                         I   E   M   R   N   A   S   Y   K   C   A   G  
  NW_001794226 IGHM*01   F   CH2 gDNA   ata gag atg agg aac gca tcg tac aag tgt gct ggg 
                                                                                        
  AY168639     IGHM*01   F   CH2 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- 





                                                                                                                        
                                       
                                        1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                         V   P   S   S   S   I   K   I   S   T   T   P   P   S   F   A 
  NW_001794226 IGHM*01   F   CH3 gDNA                   gta cca tca tca tcc atc aag atc tcc acc acc cca ccc tct ttt gcc
                                                                                                                       
  AY168639     IGHM*01   F   CH3 cDNA                   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                    _____AB_____                                            ____________
                                                    15.1    15.3                                                        
                                         13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                         G   I   F   T           T   K   S   A   K   L   V   C   S   V   T   G   M   S 
  NW_001794226 IGHM*01   F   CH3 gDNA   ggc atc ttc acc ... ... acc aag tct gcc aag ctg gtg tgc tca gtc act ggc atg tcc
                                                                                                                       
  AY168639     IGHM*01   F   CH3 cDNA   --- --- --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                        _______BC___________________                            _____________CD_________
                                                                                                45.1    45.3    45.5    
                                         30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                         T   S               D   S   L   S   I   V   W   T   Q   Y   E   G   K   E   L 
  NW_001794226 IGHM*01   F   CH3 gDNA   act tct ... ... ... gac agt ctg tcc atc gtc tgg act caa tat gaa gga aag gag ctg
                                                                                                                       
  AY168639     IGHM*01   F   CH3 cDNA   --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                        ____                                ___________________________DE_______________
                                        45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                             77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                                     T   T   K   T   S   V   S   K   I   Q   P   D                     
  NW_001794226 IGHM*01   F   CH3 gDNA   ... ... ... acg acc aaa acc agc gtg tcc aaa atc cag ccc gat ... ... ... ... ...
                                                                                                                       
  AY168639     IGHM*01   F   CH3 cDNA   ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ...


                                        ____________                                                ___EF___            
                                            85.2                                                    96.1                
                                        85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                             G   T   F   S   A   T   G   E   A   S   V   C   A   E   D   W           Q 
  NW_001794226 IGHM*01   F   CH3 gDNA   ... ggc acc ttc agt gcc acg gga gag gcc tca gtc tgt gct gaa gac tgg ... ... cag
                                                                                                                       
  AY168639     IGHM*01   F   CH3 cDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ---


                                                            _________________________FG_________________________        
                                        
                                        100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                         S   G   K   R   F   T   C   T   V   S   H   A   D           L   P   A   P   Q 
  NW_001794226 IGHM*01   F   CH3 gDNA   tcc ggg aag agg ttc acg tgt acc gtg tcc cat gcg gac ... ... ctc cca gcc ccc cag
                                                                                                                       
  AY168639     IGHM*01   F   CH3 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- ---


                                                                        
                                        
                                        120 121 122 123 124 125 126 127 
                                         S   A   Y   I   S   K   Q   K  
  NW_001794226 IGHM*01   F   CH3 gDNA   agc gcc tac atc tcc aag cag aag 
                                                                        
  AY168639     IGHM*01   F   CH3 cDNA   --- --- --- --- --- --- --- --- 





                                                                                                                            
                                            
                                            1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                         E   V   N   L   H   S   P   A   V   Y   V   L   P   P   A   S   D 
  NW_001794226 IGHM*01   F   CH4-CHS gDNA               gag gta aat ctc cac tcc cca gct gtg tac gtc ctc ccc cct gcc tcg gat
                                                                                                                           
  AY168639     IGHM*01   F   CH4-CHS cDNA               --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                        _____AB_____                                            ____________
                                                        15.1    15.3                                                        
                                             13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                             Q   L   S   L           R   E   S   A   T   L   S   C   L   V   K   S   F   S 
  NW_001794226 IGHM*01   F   CH4-CHS gDNA   cag ctc agc cta ... ... cga gag tcg gcc act ctc tcc tgc ctg gtg aag agc ttc tcc
                                                                                                                           
  AY168639     IGHM*01   F   CH4-CHS cDNA   --- --- --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                            _______BC___________________                            _____________CD_________
                                                                                                    45.1    45.3    45.5    
                                             30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                             P                   A   D   V   M   V   Q   W   L   H   K   G   Q   P   V   P 
  NW_001794226 IGHM*01   F   CH4-CHS gDNA   ccg ... ... ... ... gcc gat gtg atg gtc cag tgg ctg cat aag ggc cag ccg gtg ccc
                                                                                                                           
  AY168639     IGHM*01   F   CH4-CHS cDNA   --- ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                            ____                                ___________________________DE_______________
                                            45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                                 77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                             Q   D       K   Y   T   V   S   A   P   M   P   E   P   Q   S                 
  NW_001794226 IGHM*01   F   CH4-CHS gDNA   cag gac ... aaa tac act gtc agt gcc ccc atg cct gag ccc cag agc ... ... ... ...
                                                                                                                           
  AY168639     IGHM*01   F   CH4-CHS cDNA   --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ...


                                            ____________                                                ___EF___            
                                                85.2                                                    96.1                
                                            85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                             P   N   L   Y   F   A   Y   S   T   L   T   V   A   E   E   E   W           S 
  NW_001794226 IGHM*01   F   CH4-CHS gDNA   ccc aac ctg tac ttc gcc tac agc acc ctg acc gtg gct gag gag gag tgg ... ... agt
                                                                                                                           
  AY168639     IGHM*01   F   CH4-CHS cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ---


                                                                _________________________FG_________________________        
                                            
                                            100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                             A   G   D   S   F   T   C   V   V   V   H   E   A       L   P   L   Y   V   M 
  NW_001794226 IGHM*01   F   CH4-CHS gDNA   gcc ggg gac tct ttc acc tgc gtc gtc gtg cac gag gcc ... ctg ccc ctg tac gtg atg
                                                                                                                           
  AY168639     IGHM*01   F   CH4-CHS cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- ---


                                                                                __________________________________________CH
                                            
                                            120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 
                                             E   R   T   V   D   K   S   T               G   K   P   T   H   I   N   V   S 
  NW_001794226 IGHM*01   F   CH4-CHS gDNA   gag agg acc gtg gac aag tcc acc ... ... ... ggt aaa ccc acc cac atc aat gtc tcc
                                                                                                                           
  AY168639     IGHM*01   F   CH4-CHS cDNA   --- --- --- --- --- --- --- --- ... ... ... --- --- --- --- --- --- --- --- ---


                                            S___________________________________________
                                            
                                            140 141 142 143 144 145 146 147 148 149 150 
                                             L   V   M   S   D   T   A   N   T   C   Y  
  NW_001794226 IGHM*01   F   CH4-CHS gDNA   ctc gtg atg tcc gac acg gcc aac acc tgc tac 
                                                                                        
  AY168639     IGHM*01   F   CH4-CHS cDNA   --- --- --- --- --- --- --- --- --- --- --- 




                                     
                                        1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                        E   G   E   V   N   A   E   E   E   G   F   E   N   L   W   T   T   A   S   T 
  NW_001794226 IGHM*01   F   M1 gDNA   gaa ggt gaa gtg aat gcc gag gaa gag ggg ttt gaa aac ctg tgg acc acg gcc tct acc


                                       
                                       
                                        21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39 
                                        F   I   V   L   F   L   L   S   L   F   Y   S   T   T   V   T   L   F   K  
  NW_001794226 IGHM*01   F   M1 gDNA   ttc att gtc ctc ttc ctc ctg agc ctc ttc tac agc acg aca gtc acc ttg ttc aag 



                                       
                                       
                                        1   2  
                                        V   K  
  NW_001794226 IGHM*01   F   M2 gDNA   gtc aaa 

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
25/11/2014
Last updated:
27/05/2016
Authors:
Saida Saljoqi