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When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

	
	
	                                                                                
                                        
                                        1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                         V   W   K   V   A   P   S   V   F   P   L   T   P   S   C   E 
  NW_001794226 IGHO*01   F   CH1 gDNA                   gtt tgg aag gtg gcc cca tcc gtc ttc ccc ttg act ccc agc tgc gag
                                                                                                                       
  EU503150     IGHO*02   F   CH1 cDNA                   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                    _____AB_____                                            ____________
                                                    15.1    15.3                                                        
                                         13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                         E   V   E               L   S   E   V   T   L   G   C   L   V   T   G   Y   S 
  NW_001794226 IGHO*01   F   CH1 gDNA   gaa gta gaa ... ... ... cta tcc gag gtg acc ctg ggc tgc ctg gtg acc gga tat tcc
                                                                                                                       
  EU503150     IGHO*02   F   CH1 cDNA   --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                        _______BC___________________                            _____________CD_________
                                                                                                45.1    45.3    45.5    
                                         30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                         P                   D   P   V   K   V   D   W   S   P   S   F   Y   N   S     
  NW_001794226 IGHO*01   F   CH1 gDNA   cca ... ... ... ... gat ccc gtg aag gtc gac tgg agc cca tca ttc tac aac agc ...
                                                                                                                       
  EU503150     IGHO*02   F   CH1 cDNA   --- ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ...


                                        ____                                ___________________________DE_______________
                                        45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                             77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                                     K   A   Q   T   Y   P   S   I   L   H   P   T                     
  NW_001794226 IGHO*01   F   CH1 gDNA   ... ... ... aaa gcc cag acc tac ccc tcc atc ctc cac ccc acg ... ... ... ... ...
                                                                                                                       
  EU503150     IGHO*02   F   CH1 cDNA   ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ...


                                        ____________                                                ___EF___            
                                            85.2                                                    96.1                
                                        85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                             G   L   Y   S   L   S   S   K   I   T   V   P   A   Y   N   W             
  NW_001794226 IGHO*01   F   CH1 gDNA   ... ggg ctc tac tcg ctc agc agc aaa atc acc gtc ccc gct tac aac tgg ... ... ...
                                                                                                                       
  EU503150     IGHO*02   F   CH1 cDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ...


                                                            _________________________FG_________________________        
                                        
                                        100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                         H   N   K   V   Y   T   C   K   V   T   H   T   P           T   N   T   I   I 
  NW_001794226 IGHO*01   F   CH1 gDNA   cac aac aag gtg tac acg tgc aag gtg acc cat acg ccc ... ... aca aac acc atc atc
                                                                                                                       
  EU503150     IGHO*02   F   CH1 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- ---


                                                        
                                        
                                        120 121 122 123 
                                         S   G   N   V  
  NW_001794226 IGHO*01   F   CH1 gDNA   agt ggg aat gtc 
                                                        
  EU503150     IGHO*02   F   CH1 cDNA   --- --- --c --- 




                                       1   2   3   4   5   6   7   8   9   10  11  12  13  14  
                                       V   A   P   A   P   P   T   P   Q   T   T   T   P   V  
  NW_001794226 IGHO*01   F   H gDNA   gtt gca cca gcg cca ccc acc ccc caa acg act act cct gtt 
                                                           
  EU503150     IGHO*02   F   H gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- ---   




                                        1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                             V   T   P   A   M   K   S   P   P   A   V   R   V   V   H   S   S   C   L 
  NW_001794226 IGHO*01   F   CH2 gDNA       gtc acc ccg gcc atg aaa tct cct cca gcg gtg agg gtg gtc cac tcc tcc tgc ctc

  EU503150     IGHO*02   F   CH2 gDNA       --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

                                
                                
                                                    _____AB_____                                            ____________
                                                    15.1    15.3                                                        
                                         13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                         P   N   G   D   A       E   A   T   I   Q   L   L   C   L   I   S   D   F   S 
  NW_001794226 IGHO*01   F   CH2 gDNA   ccg aac ggg gac gcc ... gaa gcc acc atc cag cta ctt tgc ctc atc tcg gac ttc agc

  EU503150     IGHO*02   F   CH2 gDNA   --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---

                                
                                
                                        _______BC___________________                            _____________CD_________
                                                                                                45.1    45.3    45.5    
                                         30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                         P                   A   K   I   E   V   K   W   L   E   D   D   E   E   Q   D 
  NW_001794226 IGHO*01   F   CH2 gDNA   cca ... ... ... ... gcc aaa atc gag gtg aag tgg ctg gag gat gat gaa gag cag gac

  EU503150     IGHO*02   F   CH2 gDNA   --- ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

                                
                                
                                        ____                                ___________________________DE_______________
                                        45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                             77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                         G           F   Y   V   S   E   S   K   R   E   N   N   G                     
  NW_001794226 IGHO*01   F   CH2 gDNA   gga ... ... ttc tac gtt tcg gag tcc aag agg gaa aac aat ggg ... ... ... ... ...

  EU503150     IGHO*02   F   CH2 gDNA   --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ...

                                
                                
                                        ____________                                                ___EF___            
                                            85.2                                                    96.1                
                                        85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                                 K   F   S   A   Y   S   E   F   N   I   T   Q   G   E   W           L 
  NW_001794226 IGHO*01   F   CH2 gDNA   ... ... aaa ttc tct gcc tac agc gag ttc aac atc acc cag gga gag tgg ... ... ctg

  EU503150     IGHO*02   F   CH2 gDNA   ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ---

                                
                                
                                                            _________________________FG_________________________        
                                        
                                        100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                         T   G   K   T   F   T   C   S   V   R   H   M   A           S   K   K   D   I 
  NW_001794226 IGHO*01   F   CH2 gDNA   act ggc aag acc ttc acc tgc agt gta agg cac atg gcc ... ... tcc aag aag gat atc

  EU503150     IGHO*02   F   CH2 gDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- --- --- ---

                                
                                
                                                        
                                        
                                        120 121 122 123 124 125 126 127 
                                         Q   D   Y   A   R   S   C   K  
  NW_001794226 IGHO*01   F   CH2 gDNA   caa gac tac gcc agg tcc tgt aaa 

  EU503150     IGHO*02   F   CH2 gDNA   --- --- --- --- --- --- --- --- 



                                                                                                                        
                                        
                                        1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                 D   I   N   L   I   Q   N   L   K   V   S   V   S   P   P   N   P   T 
  NW_001794226 IGHO*01   F   CH3 gDNA           gac atc aac ctt atc cag aac ctc aag gtc tct gtg agc ccc cca aac cct act
                                                                                                                       
  EU503150     IGHO*02   F   CH3 cDNA           --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                    _____AB_____                                            ____________
                                                    15.1    15.3                                                        
                                         13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                         D   L   F   I           A   R   T   P   S   L   T   C   L   V   A   S   L   P 
  NW_001794226 IGHO*01   F   CH3 gDNA   gac ctc ttc att ... ... gcc cgg aca ccg tcc ctc acc tgc ctg gtg gcc agt ctg cct
                                                                                                                       
  EU503150     IGHO*02   F   CH3 cDNA   --- --- --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                        _______BC___________________                            _____________CD_________
                                                                                                45.1    45.3    45.5    
                                         30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                         D   S               E   G   I   K   L   Q   W   I   H   K   G   I   E   R     
  NW_001794226 IGHO*01   F   CH3 gDNA   gat tca ... ... ... gaa ggc atc aaa ctc cag tgg atc cac aaa ggc att gag aga ...
                                                                                                                       
  EU503150     IGHO*02   F   CH3 cDNA   --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ...


                                        ____                                ___________________________DE_______________
                                        45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                             77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                                     P   A   S   P   I   K   I   M   K   Q   P   D                     
  NW_001794226 IGHO*01   F   CH3 gDNA   ... ... ... ccc gct tct ccc atc aag ata atg aaa cag cca gat ... ... ... ... ...
                                                                                                                       
  EU503150     IGHO*02   F   CH3 cDNA   ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ...


                                        ____________                                                ___EF___            
                                            85.2                                                    96.1                
                                        85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                             G   T   F   S   A   E   S   T   L   S   I   T   L   P   E   W           M 
  NW_001794226 IGHO*01   F   CH3 gDNA   ... ggt acc ttc agt gcc gag agt acc ctg tcc atc acc ctg ccg gaa tgg ... ... atg
                                                                                                                       
  EU503150     IGHO*02   F   CH3 cDNA   ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ---


                                                            _________________________FG_________________________        
                                        
                                        100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                         E   G   E   S   F   T   C   K   V   Q   H   P   D       F   P   S   I   V   E 
  NW_001794226 IGHO*01   F   CH3 gDNA   gaa gga gaa tca ttc acg tgc aaa gtg cag cac cct gac ... ttc ccc tcc att gtt gaa
                                                                                                 S                     
  EU503150     IGHO*02   F   CH3 cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- ... -c- --- --- --- --- ---


                                                                    
                                        
                                        120 121 122 123 124 125 126 
                                         K   A   I   S   K   P   L  
  NW_001794226 IGHO*01   F   CH3 gDNA   aag gcc att tcc aag cct cta 
                                                                    
  EU503150     IGHO*02   F   CH3 cDNA   --- --- --- --- --- --- --- 



                                                                                                                           
                                            
                                            1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                             G   K   S   L   A   P   A   V   Y   V   F   P   P   H   M   D 
  NW_001794226 IGHO*01   F   CH4-CHS gDNA                   gga aag agc tta gcc ccg gcg gtt tac gtg ttc cct cca cac atg gat
                                                                                     V                                     
  EU503150     IGHO*02   F   CH4-CHS cDNA                   --- --- --- --- --- --- -t- --- --- --- --- --- --- --- --- ---


                                                        _____AB_____                                            ____________
                                                        15.1    15.3                                                        
                                             13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                             E   L   A   Q           K   D   T   L   S   L   T   C   L   A   K   S   F   F 
  NW_001794226 IGHO*01   F   CH4-CHS gDNA   gag ctg gcc caa ... ... aaa gac acc ttg agc ctc act tgt ctg gca aag agc ttc ttc
                                                                                                                           
  EU503150     IGHO*02   F   CH4-CHS cDNA   --- --- --- --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                            _______BC___________________                            _____________CD_________
                                                                                                    45.1    45.3    45.5    
                                             30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                             P                   A   D   I   A   V   Q   W   L   H   N   D   E   D   V   E 
  NW_001794226 IGHO*01   F   CH4-CHS gDNA   cct ... ... ... ... gcg gat atc gcc gtc cag tgg ctg cat aac gac gag gac gtg gag
                                                                                                                           
  EU503150     IGHO*02   F   CH4-CHS cDNA   --- ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                            ____                                ___________________________DE_______________
                                            45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                                 77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                             E   D       H   F   S   V   T   K   P   Q   K   D   L   T   G                 
  NW_001794226 IGHO*01   F   CH4-CHS gDNA   gaa gac ... cac ttt tct gtg act aag cca cag aaa gac ttg aca gga ... ... ... ...
                                                                                                                           
  EU503150     IGHO*02   F   CH4-CHS cDNA   --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ...


                                            ____________                                                ___EF___            
                                                85.2                                                    96.1                
                                            85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                             Q   G   T   F   F   L   Y   S   K   L   D   I   Q   K   S   N   W           K 
  NW_001794226 IGHO*01   F   CH4-CHS gDNA   caa ggc acg ttc ttc ctt tac agc aag cta gac atc cag aag tcc aac tgg ... ... aaa
                                                                                                                           
  EU503150     IGHO*02   F   CH4-CHS cDNA   --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ---


                                                                _________________________FG_________________________        
                                            
                                            100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                             R   G   D   S   F   T   C   M   V   G   H   E   A   L   K   R   Y   S   I     
  NW_001794226 IGHO*01   F   CH4-CHS gDNA   cgc gga gat tcc ttc acc tgc atg gtg ggc cat gag gct ctc aag cgc tac tcc ata ...
                                                                        
  EU503150     IGHO*02   F   CH4-CHS cDNA   --- --- --- --- --- --- --- 


                                                                                        __CHS__
                                            
                                            120 121 122 123 124 125 126 127 128 129 130 131 132 
                                             Q   K   T   V   R   Q   N   P               G   K  
  NW_001794226 IGHO*01   F   CH4-CHS gDNA   cag aag aca gtg cgg caa aac ccc ... ... ... ggt aaa 


                                     
                                       
                                        1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                        G   L   I   P   G   E   N   C   T   E   A   G   D   G   E   L   D   G   L   W 
  NW_001794226 IGHO*01   F   M1 gDNA   ggg ctg att ccg gga gaa aat tgc act gag gct ggt gac gga gaa cta gat ggt ctg tgg


                                       
                                       
                                        21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40 
                                        T   T   I   S   I   F   I   T   L   F   L   L   T   V   C   Y   S   A   T   I 
  NW_001794226 IGHO*01   F   M1 gDNA   act acc atc tcc atc ttc atc aca ctc ttc ctc ctc acc gtg tgt tac agt gct acc atc


                                       
                                       
                                        41  42  43  44 
                                        T   L   V   K  
  NW_001794226 IGHO*01   F   M1 gDNA   act ctc gtc aag 


                                     
                                       
                                        1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                        V   R   W   L   F   S   S   M   M   Q   I   K   Q   T   R   S   I   H   N   Y 
  NW_001794226 IGHO*01   F   M2 gDNA   gtg agg tgg ctc ttc tct tcg atg atg caa ata aag cag acc aga agc att cac aac tat


                                       
                                       
                                        21  22  23  24  25  26  27  28 
                                        R   N   M   I   L   P   G   A  
  NW_001794226 IGHO*01   F   M2 gDNA   agg aac atg atc ctt ccg ggt gcc 

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
25/11/2014
Last updated:
27/05/2016
Authors:
Saida Saljoqi