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When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

	
	
	
                                                                                                                                        
                                                        
                                                        1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1  1   2   3   4   5   6   7   8   9   10  11  12 
                                                                     G   Q   P   A   V   T   P   S   V   I   L   F   P   P   S   S   E 
  M23227       IGLC5*01 F Ig lambda-chain (C5-region)   ... ... ... ggt cag ccc gcg gtg acc ccc tcg gtc att ctg ttc ccg ccc tcc tct gag
                                                                                                                                       
  NW_003159316 IGLC5*01 F                               ... ... ... .-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                                    _____AB_____                                            ____________
                                                                    15.1    15.3                                                        
                                                         13  14  15     15.2     16  17  18  19  20  21  22  23  24  25  26  27  28  29 
                                                         E   L   K               D   N   K   A   T   L   V   C   L   I   N   D   F   Y 
  M23227       IGLC5*01 F Ig lambda-chain (C5-region)   gaa ctc aag ... ... ... gac aac aag gct acc ctg gtg tgt ctg atc aat gac ttc tac
                                                                                                                                       
  NW_003159316 IGLC5*01 F                               --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                        _______BC___________________                            _____________CD_________
                                                                                                                45.1    45.3    45.5    
                                                         30  31  34  35  36  37  38  39  40  41  42  43  44  45     45.2    45.4    45.6
                                                         P           R   T   V   K   V   N   W   K   A   D   G   N   S   V   T   Q     
  M23227       IGLC5*01 F Ig lambda-chain (C5-region)   ccc ... ... aga acc gtg aag gta aac tgg aag gca gat ggc aac tct gtc acc cag ...
                                                                                                                                       
  NW_003159316 IGLC5*01 F                               --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ...


                                                        ____                                ___________________________DE_______________
                                                        45.7                                84.1    84.3    84.5    84.7    85.6    85.4
                                                             77  78  79  80  81  82  83  84     84.2    84.4    84.6    85.7    85.5    
                                                             G   V   D   T   T   Q   P   S   K   Q   S   N                           N 
  M23227       IGLC5*01 F Ig lambda-chain (C5-region)   ... ggc gtg gac acc acc cag ccc tcc aaa cag agc aac ... ... ... ... ... ... aac
                                                                                                                                       
  NW_003159316 IGLC5*01 F                               ... --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ---


                                                        ____________                                                ___EF___            
                                                            85.2                                                    96.1                
                                                        85.3    85.1 85  86  87  88  89  90  91  92  93  94  95  96     96.2 97  98  99 
                                                         K   Y   A   A   S   S   F   L   S   L   S   A   N   Q   W           K   S   Y 
  M23227       IGLC5*01 F Ig lambda-chain (C5-region)   aag tac gcg gcc agc agc ttc ctc agc ctg tca gcc aat caa tgg ... ... aaa tcc tac
                                                                                                                                       
  NW_003159316 IGLC5*01 F                               --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---


                                                                            _________________________FG_________________________        
                                                        
                                                        100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 
                                                         Q   S   V   T   C   Q   V   T   H   E                   G   H   T   V   E   K 
  M23227       IGLC5*01 F Ig lambda-chain (C5-region)   cag agt gtc acc tgc cag gtc acg cac gag ... ... ... ... ggc cac act gtg gag aag
                                                                                                                                       
  NW_003159316 IGLC5*01 F                               --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- --- --- --- --- ---


                                                                                        
                                                        
                                                        120 121 122 123 124 125 126 127 
                                                         S   L   A   P   A   E   C   S  
  M23227       IGLC5*01 F Ig lambda-chain (C5-region)   agc ctg gcc cct gca gaa tgc tcc 
                                                                                        
  NW_003159316 IGLC5*01 F                               --- --- --- --- --- --- --- --- 

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
28/09/2012
Last updated:
27/05/2016
Authors:
Fatena Bellahcene