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When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

	
	
	                                                                                
                                                
                                                 1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                                 E   V   Q   L   Q   Q   S   G   D       G   L   V   R   P   G   A   S   V   K 
  RatNor_3_chr6 IGHV1-46*01 P V-REGION gDNA     gag gtt cag ctg cag cag tct gga gac ... ggg ctg gta agg cct ggg gct tca gtg aag
                                                                                                                               
  AABR03049802  IGHV1-46*01 P V-REGION gDNA     --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---


                                                                        _____________________CDR1-IMGT______________________    
                                                
                                                 21  22  23  24  25  26  27  28  29  30  31  32 32.1 33  34  35  36  37  38  39 
                                                 M   S   C   K   A   S   R   Y   T   F                       T   S   S   A   M 
  RatNor_3_chr6 IGHV1-46*01 P V-REGION gDNA     atg tcc tgc aag gct tct agg tac act ttc ... ... ... ... ... acc agc tct gct atg
                                                                                                                               
  AABR03049802  IGHV1-46*01 P V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- ---


                                                                                                                _______________C
                                                
                                                 40  41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59 
                                                 H   W   V   K   K   R   P   G   Q   A   L   E   *   I   G   Y   F   I   P   G 
  RatNor_3_chr6 IGHV1-46*01 P V-REGION gDNA     cac tgg gta aag aag agg ccc gga cag gcc ctg gaa tga att gga tat ttt att cct gga
                                                                                                                               
  AABR03049802  IGHV1-46*01 P V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                DR2-IMGT________________                                                        
                                                
                                                 60  61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79 
                                                         F   D   V   T   N   Y   N   Q   K   F   K       D   R   V   I   L   T 
  RatNor_3_chr6 IGHV1-46*01 P V-REGION gDNA     ... ... ttt gat gtt act aac tat aat cag aag ttt aag ... gac agg gtg ata ttg act
                                                                                                                               
  AABR03049802  IGHV1-46*01 P V-REGION gDNA     ... ... --- --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- ---


                                                                                                                                
                                                
                                                 80  81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 
                                                 A   N   S   S   S   N   R   A   Y   M   E   L   S   R   L   T   S   E   K   S 
  RatNor_3_chr6 IGHV1-46*01 P V-REGION gDNA     gca aac tca tcc tcc aac aga gcc tac atg gaa ctc agc aga ttg aca tct gaa aaa tct
                                                                                                                               
  AABR03049802  IGHV1-46*01 P V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                                        CDR3-IMG
                                                
                                                100 101 102 102A103 104 105 106 
                                                 V   V   Y       Y   C   A   R  
  RatNor_3_chr6 IGHV1-46*01 P V-REGION gDNA     gtg gtc tat ... tac tgt gca aga 
                                                                                
  AABR03049802  IGHV1-46*01 P V-REGION gDNA     --- --- --- ... --- --- --- --- 

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
04/02/2016
Last updated:
02/08/2016
Authors:
Mélanie Arrivet