IMGT Repertoire (IG and TR)

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Dots indicate gaps according to the IMGT unique numbering.
Blanks at the 5' and/or 3' end indicate partial sequences.
Asterisk (*) in the sequence indicate a STOP-CODON.
Letters in red correspond to amino acids which are polymorphic in the other alleles.
Colours are according to Color menu for mutations, Color menu for sequence alignments and Color menu for splicing types.
The nucleotide (s) in bold and colored in purple (splicing frame 1) or green (splicing frame 2) from the DONOR splice site are added at the beginning of the following exon in order to obtain and to complete the first CODON of the DOMAIN or REGION resulting from the splicing site. These first CODONs are in bold and colored in purple (splicing frame 1) or green (splicing frame 2)
N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown in green

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

                                                                                        
                                                 
                                                  1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                                  E   V   Q   L   V   E   S   G   G       G   L   V   Q   P   G   G   S   L   K 
  RatNor_2_chr6 IGHV11-12*01 F V-REGION gDNA     gaa gta cag ctg gtg gag tct gga gga ... ggc ttg gtg caa cct ggg ggg tct ctg aaa


                                                                         _____________________CDR1-IMGT______________________    
                                                 
                                                  21  22  23  24  25  26  27  28  29  30  31  32 32.1 33  34  35  36  37  38  39 
                                                  L   S   C   V   A   S   G   F   T   F                       R   D   Y   W   M 
  RatNor_2_chr6 IGHV11-12*01 F V-REGION gDNA     ctc tcc tgt gta gcc tca gga ttc act ttc ... ... ... ... ... agg gac tac tgg atg


                                                                                                                 _______________C
                                                 
                                                  40  41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59 
                                                  N   W   V   R   Q   A   P   G   K   T   M   E   W   I   G   D   I   K   P   D 
  RatNor_2_chr6 IGHV11-12*01 F V-REGION gDNA     aac tgg gtc cgg cag gct cct gga aag acc atg gag tgg att gga gat att aag cct gat


                                                 DR2-IMGT________________                                                        
                                                 
                                                  60  61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79 
                                                          G   S   N   T   N   Y   A   P   S   V   K       N   R   F   T   I   S 
  RatNor_2_chr6 IGHV11-12*01 F V-REGION gDNA     ... ... ggc agt aac aca aac tat gca cca tct gta aag ... aat aga ttc aca atc tcc


                                                                                                                                 
                                                 
                                                  80  81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 
                                                  R   D   N   A   K   S   I   L   Y   L   Q   M   S   N   M   R   S   D   Y   T 
  RatNor_2_chr6 IGHV11-12*01 F V-REGION gDNA     aga gac aat gcc aag agc atc ctg tac ctg cag atg agc aat atg aga tct gat tac aca


                                                                         _CDR3-IMGT__
                                                 
                                                 100 101 102 102A103 104 105 106 
                                                  A   T   Y       Y   C   V   R  
  RatNor_2_chr6 IGHV11-12*01 F V-REGION gDNA     gcc act tat ... tac tgt gtt aga ga

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux, Mehdi Yousfi and Perrine Pégorier).

Created:: 09/02/2016
Last updated:: 04/08/2016
Authors:: Mélanie Arrivet

IMGT Repertoire (IG and TR)

Alignment of alleles: Norway rat (Rattus norvegicus) IGHV11-12