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When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

	
	
	                                                                                
                                                
                                                 1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                                 Q   I   Q   L   K   E   S   S   P       A   V   I   E   P   S   Q   S   L   F 
  RatNor_2_chr6 IGHV12-1*01 P V-REGION gDNA     cag att cag ctt aag gag tca agt cct ... gct gtc att gag cca tca cag tca ctg ttc
                                                                                                                               
  AABR03049494  IGHV12-1*01 P V-REGION gDNA     --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---


                                                                        _____________________CDR1-IMGT______________________    
                                                
                                                 21  22  23  24  25  26  27  28  29  30  31  32 32.1 33  34  35  36  37  38  39 
                                                 L   T   *   T   V   S   G   F   S   I   T                   S   S   Y   C   W 
  RatNor_2_chr6 IGHV12-1*01 P V-REGION gDNA     ctt act tga aca gtc tct gga ttc tcc att aca ... ... ... ... agt agt tat tgc tgg
                                                                                                                               
  AABR03049494  IGHV12-1*01 P V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- --- --- --- ---


                                                                                                                _______________C
                                                
                                                 40  41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59 
                                                 H   W   A   C   Q   L   P   G   K   R   L   E   W   M   G   W   I   C   Y   K 
  RatNor_2_chr6 IGHV12-1*01 P V-REGION gDNA     cac tgg gca tgt cag ctc cca ggg aag agg tta gag tgg atg ggg tgg ata tgt tac aaa
                                                                                                                               
  AABR03049494  IGHV12-1*01 P V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                DR2-IMGT________________                                                        
                                                
                                                 60  61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79 
                                                             D   S   N   Y   Y   S   P   S   F   K       N   H   S   T   L   S 
  RatNor_2_chr6 IGHV12-1*01 P V-REGION gDNA     ... ... ... gat tca aat tac tac agt cca tcc ttc aaa ... aac cac agc acc ctc tcc
                                                                                                                               
  AABR03049494  IGHV12-1*01 P V-REGION gDNA     ... ... ... --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- ---


                                                                                                                                
                                                
                                                 80  81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 
                                                 R   D   T   T   L   N   K   F   N   I   *   L   N   S   V   T   A   E   D   T 
  RatNor_2_chr6 IGHV12-1*01 P V-REGION gDNA     aga gac aca aca ctg aac aaa ttc aat atc tag ctg aac tct gtg act gct gag gac aca
                                                                                                                               
  AABR03049494  IGHV12-1*01 P V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                                        ___CDR3-IMGT____
                                                
                                                100 101 102 102A103 104 105 106 107 108 
                                                 A   M   Y       Y   C   F   R   E   N  
  RatNor_2_chr6 IGHV12-1*01 P V-REGION gDNA     gcc atg tac ... tac tgt ttc agg gaa aac 
                                                                                        
  AABR03049494  IGHV12-1*01 P V-REGION gDNA     --- --- --- ... --- --- --- --- --- --- 

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
09/02/2016
Last updated:
02/08/2016
Authors:
Mélanie Arrivet