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When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

	
	
	                                                                                
                                                
                                                 1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                                 E   I   Q   L   K   *   *   R   P       D   L   L   Q   P   S   E   S   L   S 
  RatNor_1_chr6 IGHV2-46*01 P V-REGION gDNA     gag att caa ctg aag tag taa aga cct ... gac ctg ctg caa ccc tca gag agc ctg tct
                                                                                                                               
  AABR03048730  IGHV2-46*01 P V-REGION gDNA     --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- ---


                                                                        _____________________CDR1-IMGT______________________    
                                                
                                                 21  22  23  24  25  26  27  28  29  30  31  32 32.1 33  34  35  36  37  38  39 
                                                 L   N   C   P   L   S   D   F   S   L                       T   I   N   D   V 
  RatNor_1_chr6 IGHV2-46*01 P V-REGION gDNA     ctc aac tgc cct ctc tct gac ttc tca tta ... ... ... ... ... acc atc aat gat gta
                                                                                                                               
  AABR03048730  IGHV2-46*01 P V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- ---


                                                                                                                _______________C
                                                
                                                 40  41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59 
                                                 N   W   V   L   K   P   L   G   K   G   L   Q   W   M   L   A   I   *   S   N 
  RatNor_1_chr6 IGHV2-46*01 P V-REGION gDNA     aac tgg gtc ctc aag cca cta gga aag ggt ctg cag tgg atg cta gca ata tga agt aat
                                                                                                                               
  AABR03048730  IGHV2-46*01 P V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                DR2-IMGT________________                                                        
                                                
                                                 60  61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79 
                                                             E   I   T   L   Y   N   S   V   L   K       T   *   I   S   V   T 
  RatNor_1_chr6 IGHV2-46*01 P V-REGION gDNA     ... ... ... gaa atc aca tta tat aat tca gtt ctc aaa ... acc tga atc agt gtc acc
                                                                                                                               
  AABR03048730  IGHV2-46*01 P V-REGION gDNA     ... ... ... --- --- --- --- --- --- --- --- --- --- ... --- --- --- --- --- ---


                                                                                                                                
                                                
                                                 80  81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 
                                                 R   D   I   S   K   S   H   I   F   L   K   L   N   K   V   R   T   *   D   T 
  RatNor_1_chr6 IGHV2-46*01 P V-REGION gDNA     agg gat ata tca aaa agt cat att ttc ttg aaa ctg aac aaa gtt cga act tag gac aca
                                                                                                                               
  AABR03048730  IGHV2-46*01 P V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---


                                                                        CDR3-IMG
                                                
                                                100 101 102 102A103 104 105 106 
                                                 A   I   Y       L   F   V   R  
  RatNor_1_chr6 IGHV2-46*01 P V-REGION gDNA     gcc atc tat ... ctc ttt gtc aga 
                                                                                
  AABR03048730  IGHV2-46*01 P V-REGION gDNA     --- --- --- ... --- --- --- --- 


This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).

Created:
05/02/2016
Last updated:
02/08/2016
Authors:
Mélanie Arrivet