When several alleles are shown, the nucleotide mutations and amino acid
changes for a given codon are indicated in red letters. These polymorphic mutations are reported in
Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the
IMGT unique numbering.
Blanks indicate partial sequences (blanks at the 5' and/or 3' end).
Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 Q V Q L K E S E P G L V RatNor_1_chr6 IGHV2-50*01 P V-REGION gDNA cag gtg cag ctg aag gag tca gaa cct ... ggt ctg gta ... ... ... ... ... ... ... _____________________CDR1-IMGT______________________ 21 22 23 24 25 26 27 28 29 30 31 32 32.1 33 34 35 36 37 38 39 T A S G L L L T S N S V RatNor_1_chr6 IGHV2-50*01 P V-REGION gDNA ... ... ... act gcc tct ggg tta cta cta ... ... ... ... ... acc agc aat agt gta _______________C 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 S W I P H P P G K G L E S I G A I W S G RatNor_1_chr6 IGHV2-50*01 P V-REGION gDNA agc tgg att cca cat cct cca gga aag ggt ctg gag agt att gga gca ata tgg agt ggt DR2-IMGT________________ 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 G S T H Y S S S L K Y R L S I H RatNor_1_chr6 IGHV2-50*01 P V-REGION gDNA ... ... ... gga agc aca cat tat agt tca tct ctc aaa ... tac cga ctg agc atc cat 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 S D T S K S Q V F L K M N S M Q T D D T RatNor_1_chr6 IGHV2-50*01 P V-REGION gDNA agc gac acc tcc aaa agc caa gtt ttc tta aaa atg aac agt atg caa act gat gat aca _CDR3-IMGT__ 100 101 102 102A103 104 105 106 G T Y Y S T R RatNor_1_chr6 IGHV2-50*01 P V-REGION gDNA ggc act tac ... tac tct acc aga aa
This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux and Mehdi Yousfi).
Software material and data coming from IMGT server may be used for academic research only,
provided that it is referred to IMGT®, and cited as
"IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org
(founder and director: Marie-Paule Lefranc, Montpellier, France)."
References to cite:
Lefranc, M.-P. et al.,
Nucleic Acids Res., 27:209-212 (1999); doi: 10.1093/nar/27.1.209
Full text
Cover;
Ruiz, M. et al.,
Nucleic Acids Res., 28:219-221 (2000); doi: 10.1093/nar/28.1.219
Full text;
Lefranc, M.-P.,
Nucleic Acids Res., 29:207-209 (2001); doi: 10.1093/nar/29.1.207
Full text;
Lefranc, M.-P.,
Nucleic Acids Res., 31:307-310 (2003); doi: 10.1093/nar/gkg085
Full text;
Lefranc, M.-P. et al.,
In Silico Biol., 5, 0006 (2004) [Epub], 5:45-60 (2005);
Lefranc, M.-P. et al.,
Nucleic Acids Res., 33:D593-597 (2005); doi: 10.1093/nar/gki065
Full text;
Lefranc, M.-P. et al.,
Nucleic Acids Res., 37:D1006-1012 (2009); doi: 10.1093/nar/gkn838
Full text;
Lefranc, M.-P. et al.,
Nucleic Acids Res., 43:D413-422 (2015); doi: 10.1093/nar/gku1056
Full text.
For any other use please contact Marie-Paule Lefranc
Marie-Paule.Lefranc@igh.cnrs.fr.
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