IMGT Repertoire (IG and TR)

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

Dots indicate gaps according to the IMGT unique numbering.
Blanks at the 5' and/or 3' end indicate partial sequences.
Asterisk (*) in the sequence indicate a STOP-CODON.
Letters in red correspond to amino acids which are polymorphic in the other alleles.
Colours are according to Color menu for mutations, Color menu for sequence alignments and Color menu for splicing types.
The nucleotide (s) in bold and colored in purple (splicing frame 1) or green (splicing frame 2) from the DONOR splice site are added at the beginning of the following exon in order to obtain and to complete the first CODON of the DOMAIN or REGION resulting from the splicing site. These first CODONs are in bold and colored in purple (splicing frame 1) or green (splicing frame 2)
N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown in green

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

                                                                                        
                                               
                                                1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                                Q   V   Q   L   K   E   S   G   P       G   L   V   Q   P   S   Q   T   L   S 
  AABR03052910 IGHV2S12*01 F V-REGION gDNA     cag gtg caa ctg aag gag tca gga cct ... ggt ctg gtg cag ccc tca cag acc ctg tcc


                                                                       _____________________CDR1-IMGT______________________    
                                               
                                                21  22  23  24  25  26  27  28  29  30  31  32 32.1 33  34  35  36  37  38  39 
                                                L   T   C   T   V   S   G   F   S   L                       T   S   Y   H   V 
  AABR03052910 IGHV2S12*01 F V-REGION gDNA     ctc acc tgc act gtc tct gga ttc tca tta ... ... ... ... ... acc agc tat cat gta


                                                                                                               _______________C
                                               
                                                40  41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59 
                                                S   W   V   R   Q   P   P   G   K   G   L   E   W   I   A   A   I   S   S   G 
  AABR03052910 IGHV2S12*01 F V-REGION gDNA     agc tgg gtt cgc cag cct cca gga aag ggt ctg gag tgg att gca gca ata tca agt ggt


                                               DR2-IMGT________________                                                        
                                               
                                                60  61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79 
                                                            G   S   T   Y   Y   N   S   A   L   K       S   R   L   S   I   S 
  AABR03052910 IGHV2S12*01 F V-REGION gDNA     ... ... ... gga agc aca tat tat aat tca gct ctc aaa ... tcc cga ctg agc atc agc


                                                                                                                               
                                               
                                                80  81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 
                                                R   D   T   S   K   S   Q   V   F   L   K   M   N   S   L   Q   T   E   D   T 
  AABR03052910 IGHV2S12*01 F V-REGION gDNA     agg gac acc tcc aag agc caa gtt ttc tta aaa atg aac agt ctg caa act gaa gac aca


                                                                       CDR3-IMG
                                               
                                               100 101 102 102A103 104 105 106 
                                                A   M   Y       F   C   A   R  
  AABR03052910 IGHV2S12*01 F V-REGION gDNA     gcc atg tac ... ttc tgt gcc aga

This alignment of allele is generated by IMGT/OutilAllele (Patrice Duroux, Mehdi Yousfi and Perrine Pégorier).

Created:: 05/02/2016
Last updated:: 02/08/2016
Authors:: Mélanie Arrivet

IMGT Repertoire (IG and TR)

Alignment of alleles: Norway rat (Rattus norvegicus) IGHV2S12